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Doctor insights on: Protein's Activity W Reflex

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Tested for anti cardiolipin IgM is negative (0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?

Tested for anti cardiolipin IgM is negative (0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?

Not sure: I am not sure I understand the question. I suspect you are being evaluated for a blood clotting disorder and you have an elevated anticardiolipin IgG. One test however does not make the diagnosis of anti-phospholipid syndrome. ...Read more

Protein (Definition)

Proteins are large molecules made up of a smaller class of molecules called amino acids. Proteins play an enormous role in the function of our bodies including enzymes, messengers, replicating dna, ...Read more


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Protein S 107% (60-130) Protein C 67%. (70-140) should I be concerned with low protein C results?

Protein S 107% (60-130) Protein C 67%. (70-140) should I be concerned with low protein C results?

No: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the results you provided are not a cause for concern. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Can a person have both a protein c and protein s deficiency?

Can a person have both a protein c and protein s deficiency?

Yes: Combined protein c and protein s deficiencies can occur in one individual who is unlucky enough to inherit both autosomal dominant traits. This is very rare. Care should be taken as to when to check levels of these two proteins since both of them would be low in patients taking warfarin since both are also vitamin k-dependent in their production in the liver. ...Read more

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Having protein s deficiency causes you to be sleepy?

Having protein s deficiency causes you to be sleepy?

No: Protein s deficiency is a cause of hypercoaguable state (which means that there is an increased risk developing blood clots). There is no association between this deficiency and sleepiness of which I am aware. ...Read more

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If I have a protein s deficiency do I need to take blood thinners?

If I have a protein s deficiency do I need to take blood thinners?

See hematologist: Protein s deficiency can vary - some patients have very mild forms and some much more severe. You need to know how severe your particular case is, and then decide if you have other risk factors for clotting - things like birth control or hormonal therapy, family history of clots/strokes, smoking status. All the things need to be considered together to see if you are a prospect for blood thinners. ...Read more

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"protein s-functional" came back high?

No problem.: There is no clinical meaning to a high protein s level. Deficiency of protein s is associated with a risk of abnormal blood clotting, but there is no risk associated with a high level. ...Read more

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What are normal test results of a protein s assay?

What are normal test results of a protein s assay?

Functional activity: The test is usually for functional activity rather than quantification of protein and is reported as a percentage with 60-150% of normal being the usual range in healthy individuals. ...Read more

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What does it mean when elevated levels of protein c and protein s?

See below: These are blood tests that we usually do to screen people who we think have a predisposition to have blood clots. By themselves they don't mean anything as normal people can have elevated levels. If you have a strong family history of blood clots or if u have had a blood clot yourself then this test could have significance. The best thing to do would be to discuss with a hematologist. ...Read more

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How does protein s and c interact with the clotting process, specifically relating to aps? Can anything be done diet-wise to normalize that?

How does protein s and c interact with the clotting process, specifically relating to aps? Can anything be done diet-wise to normalize that?

See below: Protein s is a co-facotr for protein c and thus these two are related. Neither is related to aps. Levels of proteins s and c are genetically determined and diet is not likely to affect the levels of these proteins. ...Read more

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What are protein c and protein s tests?

Tests for clotting: People whose blood tends to clot excessively can have deep vein thrombosis (clots in veins in the legs or abdomen) or pulmonary emboli (clots that travel to the lungs). A deficiency of protein c or protein s, among other things, can cause excess clotting. Tests for protein c or s are used to diagnose levels of these proteins in the blood. ...Read more

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Dear sir, what is protein c and protein s I need your info about it?

Dear sir, what is protein c and protein s I need your info about it?

Blood coagulation: Protein C and S work together in regulating the clotting of blood. These proteins are important in controlling the amount of blood clot formation inside blood vessels. Deficiency of either can lead to venous blood clot formation. Deficiencies of both are not that common. ...Read more

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If my protein s free antigen is low (0.51) what does this mean?

If my protein s free antigen is low (0.51) what does this mean?

Clots: Protein S deficiency puts patients at an increased risk for venous thrombosis (blood clots). Also possible for recurrent miscarriage and complications of pregnancy. ...Read more

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They took 10vials of blood from me for protein s and c blood test. Is it too much or normal, I was just shocked.

They took 10vials of blood from me for protein s and c blood test. Is it too much or normal, I was just shocked.

Protein C & s: It does seem like a lot. Perhaps your doctor was looking to perform out her tests with the blood? ...Read more

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I am diagnosed with protein S deficiency. My total level was 75, and the free protein S level was 32 Can someone help me understand this condition.?

I am diagnosed with protein S deficiency. My total level was 75, and the free protein S level was 32 Can someone help me understand this condition.?

Protein S deficiency: Bottom line, you are at increased risk for DVT's, deep vein thrombosis. You need to see your doctor or a hematologist. You may need to be on an anticoagulant medicine. Best of luck. ...Read more

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In protein's electrophoresis Is polyclonal gammopathy alway pathological? Thanks

In protein's electrophoresis Is polyclonal gammopathy alway pathological? Thanks

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, What is total gamma globulin level? If it is more than 2.0 gm/dL it needs to be evaluated. There are many causes of polyclonal gammopathy., and some of those are serious. ...Read more

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I just received some test results back that said my protein c is high, protein s is low my pai-1 is high, my chloride is high and my co2 is low?

I just received some test results back that said my protein c is high, protein s is low my pai-1 is high, my chloride is high and my co2 is low?

Clot risk.: A high protein c has no significance, only low. A low protein s, like protein c, is a risk for having abnormal blood clots or pregancy complications. Protein c and s cooperate to dissolve blood clots. Pai-1 blocks the clot dissolving pathway, so a high level also is a risk for abnormal clots. A high chloride and low co2 are part of the salts in the blood that are regulated by the kidneys. ...Read more

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My platelet count is 154, it was 320 4 months ago plus I have protein s def. I've been bruising a lot lately should I worry?

Not about this: Platelet count in a woman often varies by this much or more over the course of the month. If you're being treated for protein s deficiency with an anticoagulant, make your hematologist aware of the bruising tendency, and in any case keep a diary of how much your bruise. Best wishes. ...Read more