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Doctor insights on: Protein's Activity W Reflex

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Tested for anti cardiolipin IgM is negative(0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?

Tested for anti cardiolipin IgM is negative(0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?

Not sure: I am not sure I understand the question. I suspect you are being evaluated for a blood clotting disorder and you have an elevated anticardiolipin IgG. One test however does not make the diagnosis of anti-phospholipid syndrome. ...Read more

Protein (Definition)

Proteins are large molecules made up of a smaller class of molecules called amino acids. Proteins play an enormous role in the function of our bodies including enzymes, messengers, replicating dna, ...Read more


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Can a person have both a protein c and protein s deficiency?

Can a person have both a protein c and protein s deficiency?

Yes: Combined protein c and protein s deficiencies can occur in one individual who is unlucky enough to inherit both autosomal dominant traits. This is very rare. Care should be taken as to when to check levels of these two proteins since both of them would be low in patients taking warfarin since both are also vitamin k-dependent in their production in the liver. ...Read more

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Having protein s deficiency causes you to be sleepy?

Having protein s deficiency causes you to be sleepy?

No: Protein s deficiency is a cause of hypercoaguable state (which means that there is an increased risk developing blood clots). There is no association between this deficiency and sleepiness of which I am aware. ...Read more

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If I have a protein s deficiency do I need to take blood thinners?

If I have a protein s deficiency do I need to take blood thinners?

See hematologist: Protein s deficiency can vary - some patients have very mild forms and some much more severe. You need to know how severe your particular case is, and then decide if you have other risk factors for clotting - things like birth control or hormonal therapy, family history of clots/strokes, smoking status. All the things need to be considered together to see if you are a prospect for blood thinners. ...Read more

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"protein s-functional" came back high?

"protein s-functional" came back high?

No problem.: There is no clinical meaning to a high protein s level. Deficiency of protein s is associated with a risk of abnormal blood clotting, but there is no risk associated with a high level. ...Read more

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What are normal test results of a protein s assay?

What are normal test results of a protein s assay?

Functional activity: The test is usually for functional activity rather than quantification of protein and is reported as a percentage with 60-150% of normal being the usual range in healthy individuals. ...Read more

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What does it mean when elevated levels of protein c and protein s ?

See below : These are blood tests that we usually do to screen people who we think have a predisposition to have blood clots. By themselves they don't mean anything as normal people can have elevated levels. If you have a strong family history of blood clots or if u have had a blood clot yourself then this test could have significance. The best thing to do would be to discuss with a hematologist. ...Read more

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How does protein s and c interact with the clotting process, specifically relating to aps? Can anything be done diet-wise to normalize that?

How does protein s and c interact with the clotting process, specifically relating to aps? Can anything be done diet-wise to normalize that?

See below: Protein s is a co-facotr for protein c and thus these two are related. Neither is related to aps. Levels of proteins s and c are genetically determined and diet is not likely to affect the levels of these proteins. ...Read more