Doctor insights on:
Protease Amylase Lipase Enzymes
They may: It is not unusual for patients to have slight elevations in their liver enzymes with gall stones. This is probably caused by sub clinical inflammation in the gall bladder. Significant elevations are seen in acute cholecystitis and elevation of the bilirubin can be due due common duct stones with obstruction. ...Read more
Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more
Health fraud: Giving the pancreatic enzymes that help in pancreatic insufficiency (cystic fibrosis, chronic pancreatic scarring) as a cancer treatment is a cynical, cruel fraud. It's often packaged with "detoxification" and coffee enemas. Don't pay money to the people who've tried to deceive you on the thought "what if it did work?". ...Read moreSee 1 more doctor answer
Depends: Elevated liver enzymes can be due to a number of causes. Without knowing more information, it is difficult to answer. However, depending on the degree of elevation and the type of "liver enzymes" that are elevated, it can be due to fatty liver disease (very common now a days) or inflammation from other causes. Discuss with your pcp or a liver specialist what the next steps are. ...Read moreSee 2 more doctor answers
Trypsin: Protease is a general term of any enzyme that breaks down proteins and includes, trypsin, and chymotrypsin. ...Read more
Are pancreatic enzymes (amylase and lipase) always elevated if pancreatic cancer is present?? What about insulin blood level?
Workup: If available, get a proper genetic workup even if no one else in the family is affected. If your amylase is high but lipase normal and there is nothing on imaging pointing to the pancreas, this may be macroamylasemia. If the pancreatitis is real, checking the cystic fibrosis and trypsinogen loci is indicated. This may be one piece in the puzzle. Be persistent. ...Read more
Normal pancreatic enzymes, normal liver enzymes, normal CBC, normal ESR & C-RP. does this rule out pancreatic and liver cancer?
Why do you ask?: Why would you think you have this stuff at age 20? You've written about this before. You owe it to yourself and those who love you to get with someone who can help you out these thoughts out of your mind and get on with studying, getting job skills and experience, perhaps finding romance and meaningful things to enjoy. To be brave, act brave. You're anything but helpless. ...Read more
History & physical: If the pancreas is inflamed or damaged, amylase and lipase are often up, and it's not subtle. If your pancreas isn't functioning properly, you'll be losing weight with no explanation and probably have diarrhea / steatorrhea. Your physician can check your stool for pancreatic enzymes. It's rare but with a suggestive history, a screen may show something that could respond to enzyme replacement. ...Read more
Total bilirubin 2.5 (Elevated), Direct bilirubin 0.5 (Elevated), Indirect bilirubin 2.0 (Elevated) All other liver enzymes normal. What causes this?
Rerun test: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you need to re do the tests in non-fasting state. With the exception of elevated direct bilirubin, the findings are consistent with Gilbert syndrome, which is not a disease. See this site for more info: http://www.mayoclinic.org/diseases-conditions/gilberts-syndrome/basics/definition/con-20024904 ...Read more
Mirtazapine-elevated liver enzymes. Does drug induced elevated liver enzymes mean permanent liver damage?
Calprotectin 95, ALT & AST chronically fluctuating elevated,sigmoidoscopy normal,MRCP normal, could it be IBD causing elevated liver enzyme ?
IBD complication AIH: The calprotectin level (I'm assuming it's a stool test) is rather high 4 ur age (normal is less than 51 ug/g stool), which seems confirm IBD but unfortunately didn't spare u a sigmoidoscopy. Caveat: proton pump inhibitors like Prilosec falsely elevate calprotectin. Nonetheless, a common complication of IBD is autoimmune hepatitis (AIH) which can cause fluctuating liver enzymes & damage. TTY GI do ...Read more
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