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Doctor insights on: Propylthiouracil

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Dr. Kenneth Pennington
98 doctors shared insights

Propylthiouracil (Overview)

Propythiouracil (PTU) can be used to control an overactive thyroid in the first trimester. PTU should be used with caution or avoided in the second and third trimester to avoid maternal liver complications.


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What are the side effect propylthiouracil 50 mg?

What are the side effect propylthiouracil 50 mg?

Rash, liver, wbc: The most common side effect is rash, as ptu (propylthiouracil) is a sulfa drug. Liver inflammation can occur occasionally, so we typically monitor liver function tests. Rarely, one can develop low white count leading to infection. ...Read more

Dr. Kenneth Pennington
98 doctors shared insights

Propylthiouracil (Overview)

Propythiouracil (PTU) can be used to control an overactive thyroid in the first trimester. PTU should be used with caution or avoided in the second and third trimester to avoid maternal liver complications.


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Can you have a bad reaction to propylthiouracil (ptu)?

Can you have a bad reaction to propylthiouracil (ptu)?

It's possible.: Ptu (propylthiouracil) can cause a skin reaction (hives, rarely), liver problems (more rare, but that's why it's use is severely restricted these days), and a drop in the white blood cell count (extremely rare). ...Read more

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Hi doctors my sister is 15yrs old and she has hypertyroid. Her doctor prescribe ptu (propylthiouracil) 100mg bid and propranolol 40mg daily for 9 months but nathing chan?

Hi doctors my sister is 15yrs old and she has hypertyroid. Her doctor prescribe ptu (propylthiouracil) 100mg bid and propranolol 40mg daily for 9 months but nathing chan?

Need new doctor?: Ptu (propylthiouracil) is not recommended due to potential for liver damage. When given, needs to be 3x/day. Propranolol will not work for the full 24 hours. If there has been no change in 9 mos she needs to have her regimen changed (and maybe her doctor as well). She should be seeing a pediatric endocrinologist. ...Read more

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How come propylthiouracil used to treat hyperthyroidism?

How come propylthiouracil used to treat hyperthyroidism?

It is one treatment: It blocks the overproduction of thyoid hormone by the overactive thyroid gland and reduces conversion of T4 to the more active t3 (liothyronine) at peripheral tissues. ...Read more

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What are other medications for surgery other than carbimazole and propylthiouracil (ptu) and how effective are they?

What are other medications for surgery other than carbimazole and propylthiouracil (ptu) and how effective are they?

Hyperthyroid : These anti thyroid medication are used to treat hyperthyroidism primarily grave's disease. Ptu (propylthiouracil) now has a black box warning on it in the us because of some patients developing liver failure on it. Few stay in remission once off of meds. Many endocrinologists in the us favor radioablation of the thyroid for permanent treatment for those eligible. Surgery usually not 1st choice. ...Read more

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Is it safe to take propylthiouracil while pregnant or breastfeeding?

Is it safe to take propylthiouracil while pregnant or breastfeeding?

Yes: Propylthiouracil (ptu) is the preferred treatment for hyperthyroidism like grave's disease during pregnancy and nursing. Thyroid hormone levels need to be monitored closely as they can change during pregnancy. The alternative, Methimazole is recommended for non-pregnant or nursing patients. ...Read more

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How long are the side effects and symptoms of propylthiouracil supposed to last?

How long are the side effects and symptoms of propylthiouracil supposed to last?

Depends on side effc: Side effects such as skin reaction and joint pain tend to resolve within 1-2 weeks from cessation. Bone marrow suppression can take a bit longer. Liver damage however can be irreversible. Please talk with your doctor if you are experiencing any usual symptoms. ...Read more

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Tell me about ptu (propylthiouracil) effects/?

Liver toxicity: Fulminant hepatic failure is the most serious adverse effect (black warning exist for such risk). Other side effects include rash , joint pain and rarely bone marrow suppression. ...Read more

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For how long time did ptu (propylthiouracil) taken?

For how long time did ptu (propylthiouracil) taken?

PTU (propylthiouracil): Ptu (propylthiouracil) has an ongoing risk on bone marrow suppression and liver toxicity which is low but real. Some, but not all practitioners limit it's use to 1-2 years and then move to permanent management like radioactive iodine or surgery. ...Read more

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Can you have a bad reaction to propylthiouracil (ptu)?

It's possible.: Ptu (propylthiouracil) can cause a skin reaction (hives, rarely), liver problems (more rare, but that's why it's use is severely restricted these days), and a drop in the white blood cell count (extremely rare). ...Read more

Dr. Daniel Saurborn
47 doctors shared insights

Ptu (Definition)

PTU is a thyroid agent which is a ...Read more