Doctor insights on:
Yes: Each year there are at least 4-6 different strains circling the globe & air travel spreads it quickly. Only 3-4 strains can be put into the yearly shot without weakening the protection for each strain. These are picked by amount of world activity. There is always a chance someone who gets the shot can get a flu strain not in the vaccine but it protects for most. ...Read moreSee 2 more doctor answers
Only here in the US: If you compare a MAP of malaria prevalence (number of cases) to a MAP of sickle cell disease prevalence, they are almost super-imposable with one exception; the United States. The prevalence of sickle cell anemia in the us is as high as some african countries with lower malaria frequencies, but our only malaria comes from travelers. ...Read more
Is there a possible link between hereditary hemochromatosis, polycythemia vera (primary jak2 mutation), & idiopathic pulmonary arterial hypertension?
Look to west coast: In 2014 we lost about 40 babies to whooping cough, mostly on the west coast among anti-vaccine families. There were in excess of 40,000 cases nationwide.Back in the mid 1990's, we had only 2500 cases/yr nationwide and no deaths. The germs are around and ready to infect or kill.The success of the DTP has made many think it is no longer an issue. So sad. ...Read moreSee 2 more doctor answers
Sickle and malaria: Patients with sickle cell disease are protected againts severe and complicated malaria infection- by 2 mechanism: -1. Cells infected with malaria paracytes had accelerated sickling compared with noninfected cells- and as the result the cell would be destroyed/ promoting removal of infected cells from the circulation `2.Impaired paracyte growth due to reduce o2 content in sickle cell. ...Read moreSee 1 more doctor answer
Yes: Sexuality period is a risk factor for hepatitis b, so anyone who is sexually active is at risk. Some consider homosexuality as a separate risk factor because anal intercourse has a slightly higher chance of transmission, but this line is really blurred. The main point is that all sexual practices translate a risk of hepatitis b and other sexually transmitted infections. ...Read moreSee 2 more doctor answers
PBC Dupuytrens: Una ware of this association will check ...Read more
No: Both are very common and this is probably a coincidence. The factor v gene isn't part of the pathway by which new vessels form, and this speaks against there being any correlation. There are a few other genetic syndromes with distinctive hemangiomas, but factor v has not been linked to any. ...Read more
I Don't Think So: I'm guessing a bit as to what you mean by your question. Sickle cell anemia is caused by a gene mutation on both copies of the beta globin gene. In that sense it is a genetic disease. However, a number of other factors, some of them environmental, can influence the type and severity of problems that patients with ssa have. ...Read more
17 years female of stunted growth with 1ry amenorrhea & no sexuall charcter ( high ESR & microcytic anemia )?
It doesn't appear so: I can find no reports of an association between sickle cell anemia and jak2 mutations. Jak2 is a gene involved in promoting growth of red blood cells. The confusion may have arisen from some reports suggesting that stimulators of jak2 might be useful in gene therapy treatments for sickle cell disease. ...Read more
Maternally derived: Mutations in mitochondrial dna cause defective energy production impacting cell function in the 65 known mitochondrial disorders.Muscle weakness ( like ptosis/droopy eyelids), blindness, deafness & progressive neurologic disorder with developmental regression +/- autistic behaviors are some known symptoms. Some organs may be affected & not others. Mother may be unaffected or mildly affected. ...Read more
If you mean....: Is the beta globin gene transmitted on a sex chromosome (either x or y), the answer is no. The beta globin locus is autosomal, and classical sickle cell disease (hgbss disease) displays autosomal recessive inheritance. Boys and girls are equally likely to inherit the beta-s allele from an affected or carrier parent, and if they inherit a beta-s allele from each parent, they will have disease. ...Read more
For a State Agency safety written program update I'm researching, looking for a credible answer & source; is there currently a poison ivy vaccine?
I doubt it: people may be working on it. one approach: Arch Dermatol Res. 1999 Dec;291(12):652-8. ...Read more
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