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Doctor insights on: Prometrium Progestin Based Agent

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Which is better: crinone (progesterone gel) or standard progesterone suppositories?

Which is better: crinone (progesterone gel) or standard progesterone suppositories?

Crinone (progesterone gel).: Crinone (progesterone gel) is a more absorbable formulation of vaginal Progesterone and approved to prevent preterm birth in women with very short cervix (<15-20 mm) by transvaginal prenatal ultrasound. Suppositories are not approved for that indication! use Crinone (progesterone gel) 8% (90 mg per 1.125g) nightly until 37 weeks if your physician agrees. ...Read more

Dr. Elizabeth Hutson
115 doctors shared insights

Micronized Progesterone (Definition)

Micronized progesterone is a progestin-based agent which is a kind of women's ...Read more


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What is prometrium (micronized progesterone) used for?

Progesterone: Prometrium (micronized progesterone) is a bio identical hormone which is used to initiate withdrawal bleeding after a cycle where ovulation doesn't occur or it can be used to support a pregnancy when the Progesterone level is too low. ...Read more

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When adding estrogen to prometrium (micronized progesterone) for perimenopausal relief how is amt. Determined?

When adding estrogen to prometrium (micronized progesterone) for perimenopausal relief how is amt. Determined?

Starting dose: Most people will use 1-2 mg which are the lowest doses for effectiveness, sometime we go higher if symptoms are persistant. ...Read more

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When prometrium (micronized progesterone) stimulates instead of sedates a perimenopausal woman what should be taken? Estrogen in combo with prometrium (micronized progesterone)?

When prometrium (micronized progesterone) stimulates instead of sedates a perimenopausal woman what should be taken? Estrogen in combo with prometrium (micronized progesterone)?

Go see your doctor: While our impression of estrogen for perimenopausal women has changed dramatically over the last decade, it still should be used for right reason, and sedation is not one of them. So go see your prescribing doctor & tell her/him about your side effects so that s/he can offer you some alternatives (rather than just throw more medications at you). ...Read more

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Please describe the medication: prometrium (micronized progesterone)?

Progesterone: It is a micronized progesterone. It can also be called a bio identical progesterone. The chemical structure is the same as the Progesterone produced by the ovary in a woman's body. ...Read more

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Which synthetic estrogen is safest, Estradiol Valerate, Mestranol, or Ethinyl Estradiol?

Which synthetic estrogen is safest, Estradiol Valerate, Mestranol, or Ethinyl Estradiol?

Synthetic meds: 1st no such thing as free lunch ie there's always some potential risk or side effect. 2nd FDA only approves meds which they deem benefit greater than risk (tho obviously not w/o disagreement & controversy). 3rd no studies demonstrate benefit of any oral estrogen over another tho some studies suggest topical safe than oral. 4th Natural isn't safe than synthetic ie tobacco is natural but isn't safe! ...Read more

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Would taking prometrium (micronized progesterone) effect a liver hemangioma?

Doctor should help: Some hemangiomas will respond differently than others. The manufacturer recommends against taking Prometrium (micronized progesterone) if you have any 'liver disease.' as with all decisions you have to weigh risks to benefits, but under no circumstances shoudl you decide without your doctor closely invovled. ...Read more

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49yr f - alora patch (.05) & prometrium (micronized progesterone) (100mg) bleed& clots by 5 days on meds. Prob hormonal imbalance. How to balance? More estr or prometrium (micronized progesterone) ?

Prob. less estrogen: Estrogen causes the lining of the uterus to thicken and later this causes the bleeding. You probably need less estrogen and possible more Progesterone depending on other symptoms. See your doctor to get adjusted. ...Read more

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Is the micronized progesterone any different from regular progesterone?

Is the micronized progesterone any different from regular progesterone?

Micronized P4: Practically speaking, for someone using progsterone, no. Progesterone does not dissovle well in water, and so it's poorly absorbed unless micronized in oil. You can think of 'micronized' as meaning dissolved, although it's not quite identical. ...Read more

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I take the estrogen patch v-dot ans prometrium (micronized progesterone) but can II start bio-identical progestrone with the patch?

Yes: Bio identical Progesterone obtained from reputable compounding pharmacies , works just as well and can be titrated easily. However you can take one or the other , you can replace the Prometrium (micronized progesterone) with the bio identical progesterone. ...Read more

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What is the standard starting dose of progesterone bioidentical hormone cream?

What is the standard starting dose of progesterone bioidentical hormone cream?

See below: Knowing your present level help direct treatment...Saliva testing can help tell you what is out of balance. This tells you how much free hormone is available, and then with the help of some one experienced in natural hormone therapy many corrections can be corrected. ...Read more

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What are the safety concenrs with bioidentical oral micronized progesterone?

What are the safety concenrs with bioidentical oral micronized progesterone?

None: Progesterone is progesterone. All Progesterone comes from the same plant based source and even the synthetic progestins like Provera (medroxyprogesterone) have Progesterone as their base. Micronized Progesterone is exactly Progesterone while synthetic progestins are progesterones that have been chemically modified. Progesterone comes from the ovary or from conversion from the adrenal hormone dhea. ...Read more

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Hormone replacement- is the dose and duration of prometrium (micronized progesterone) used in menopause dependent on the dose of estrogen being used by the patient.?

Hormone replacement-  is the dose and duration of prometrium (micronized progesterone) used in menopause dependent on the dose of estrogen being used by the patient.?

Not necessarily: If you still have a uterus, then you need a combination of estrogen and progesterone. The Progesterone can by taken continuously or in a cyclic fashion. Remember, you are only using the minimum dose of hormones to treat the symptoms that are bothering you. Discuss these doses with your doctor. ...Read more

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Prempro (conjugated estrogens and medroxyprogesterone) works well but expensive. What is exact alternative?

Prempro (conjugated estrogens and medroxyprogesterone) works well but expensive. What is exact alternative?

Options: There are options. Prempro has different dosages of estrogen and Progesterone component. Estrogen (estradiol) comes in 0.3mg, 0.45mg, and 0.625mg. The Medroxyprogesterone acetate comes as 1.5mg 2.5mg and 5mg. As your dosage of estrogen goes up, so does progesterone. You can take estrogen as pill or patch. I like the patch. And then take Provera (medroxyprogesterone) for Progesterone (2.5 or 5.0mg). ...Read more

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Is discharge normal with prometrium (micronized progesterone) suppositories?

Yes: With almost all the progesterone formulations it will be normal to have vaginal discharge as the progesterone liquefies. A product called "Crinone" does not have this effect and works the same. ...Read more

Dr. Heidi Fowler
113 doctors shared insights

Prometrium (Definition)

Prometrium is a progestin-based agent which is a kind of women's ...Read more