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Doctor insights on: Proleukin

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Dr. Patricia Foster
7 doctors shared insights

Proleukin (Overview)

Proleukin is a cancer-related immune system affecting agent which is a kind of cancer drug.


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Discuss monoclonal antibody production?

Discuss monoclonal antibody production?

Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more

Dr. Patricia Foster
7 doctors shared insights

Proleukin (Overview)

Proleukin is a cancer-related immune system affecting agent which is a kind of cancer drug.


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Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Ongoing Study: According to clinicaltrials.Gov, the phase i trial is still on-going; there are no results yet. ...Read more

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Results of trial of proleukin (aldesleukin) in recent onset type 1 diabetes?

Ongoing Study: According to clinicaltrials.Gov, the phase i trial is still on-going; there are no results yet. ...Read more

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Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Possibly: If the leukemia develops out of a myelodysplasia and has evidence of a 5q-, then possibly. But, the results are mediocre at best. Not curative by any stretch but could possibly slow the leukemia down for a short time. Hope this helps. ...Read more

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Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trial of proleukin (aldesleukin) and Rapamune in recent onset type 1 diabetes, what to do?

Phase I trials: This is a question best asked of your endocrine specialist. I suppose you are contemplating entering the trial? Do your research and make sure that your questions are answered, be sure that you are willing to make the necessary time commitment. Discuss with family and trusted peers/friends before deciding to join a study. http://clinicaltrials.gov/show/NCT00525889 ...Read more

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Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

Can phase I trial of proleukin (aldesleukin) and Rapamune lead to type 1 diabetes?

NIH study: The combination of these drugs is being studied in adult patients already diagnosed with type 1 diabetes. The thought is that the combination might help slow down the progress of diabetes. The study isn't complete yet. If there is another phase 1 trial using these drugs in a different study, the investigator should be approached with your question. ...Read more

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Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Mylotarg-cytarabine: Open these links: http://www.Drugs.Com/mtm/mylotarg.Html http://www.Drugs.Com/mtm/cytarabine.Html.

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Is neulasta (pegfilgrastim) needed with weekly taxol?

Is neulasta (pegfilgrastim) needed with weekly taxol?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

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Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more

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What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?

What makes Trovax different from other kidney cancer meds (like nexavar, proleukin, torisel, (temsirolimus) sutent)?

Other drugs worked: Nexavar, torisel, and sutent all received FDA approval because they improved progression free survival. The initial Trovax trial was terminated early because there was little or no prospect of demonstrating a statistically significant survival benefit compared to placebo. http://clincancerres.aacrjournals.org/content/16/22/5539.long ...Read more

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Is cytoxan (cyclophosphamide) chemotherapy?

Is cytoxan (cyclophosphamide) chemotherapy?

Yes.: Generic name of Cytoxan is cyclophosphamide. It is a drug commonly used to treat a variety of cancers, but may also be used to treat some autoimmune disorders, such as lupus. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Describe polyclonal and monoclonal antibody production?

Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more

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Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Good options: Both are good options. It will depend on safety profiles and the need of using steroid with zytiga (abiraterone acetate) but not for extandi. Discuss further with your oncologist to select which one is the best for you. ...Read more

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Neulasta (pegfilgrastim) cause white blood cell spike?

Neulasta (pegfilgrastim) cause white blood cell spike?

Yes!!: This is exactly what Neulasta (pegfilgrastim) does. It increases your white blood cell count, and it can sometimes raise it to very high levels. ...Read more

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What is monoclonal gammopathie IgM kappa?

What is monoclonal gammopathie IgM kappa?

Plasma cell disorder: Monoclonal gammopathy refers to an abnormal production of proteins by cells in the immune system (plasma cells) that are growing out of control. It can be one of the signs of myeloma. A hematologist-oncologist can help. ...Read more

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Mult.Myeloma relapsed after treatment with velcade (bortezomib), (bortezomib) melphalan&dexamethasone. Melphalan stopped in dec, velcade (bortezomib) in april. Now takes carfilzomib& dexamethasone fever39.5. No infections.What causes fever?

Mult.Myeloma relapsed  after treatment with velcade (bortezomib), (bortezomib) melphalan&dexamethasone. Melphalan stopped in dec, velcade (bortezomib) in april. Now takes carfilzomib& dexamethasone fever39.5. No infections.What causes fever?

Fever could be side : Effects of the chemotherapeutic agents and steroids considering there's no blood infection. Tylenol (acetaminophen) should help control the fever. Follow up with your oncologist. God bless you! http://www.Livestrong.Com/article/36171-herbs-cancer/. ...Read more

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M spike in.Urinie protine alpha 2?

M spike in.Urinie protine alpha 2?

An M spike in either: The urine or the serum reflects the production of a single (monoclonal) globulin. It is found in multiple myeloma, a malignancy of the plasma cells that make antibody, and also can be found in so-called monoclonal gammopathy of unclear significance (mgus) which is generally benign. ...Read more

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Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?

Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or  rituximab+bendamustine?

There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft. ...Read more

Dr. Andrew Seibert
13 doctors shared insights

Aldesleukin (Definition)

Aldesleukin is a cancer-related immune system affecting agent which is a ...Read more