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Doctor insights on: Prokinetics Domperidone Or Metoclopramide And Indigestion

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How effective are reglan (metoclopramide) and domperidone?

How effective are reglan (metoclopramide) and domperidone?

Domperidone: "Food and Drug Administration (FDA) stresses that domperidone is not an FDA-approved drug, and that it may not be legally marketed in the US." "FDA's concern about the potential health risks associated with the use of domperidone in lactating women. These risks include cardiac arrhythmias, cardiac arrest, and sudden death." July 31, 2013 ...Read more

Reglan (Definition)

Metoclopramide increases emptying of food from the stomach and decreases symptoms of nausea, vomiting, heartburn, and fullness,. It should ideally be taken 30 minutes before meals. It's use in pregnancy should be reserved for severe conditions where the risks to the baby of not treating exceed the potential ...Read more


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Diagnosed with mild gastropatesisgiven reglan (metoclopramide) but due to its side effects too scared to take doc gave me prescription for domperidone is this safer?

Diagnosed with mild gastropatesisgiven reglan (metoclopramide) but due to its side effects too scared to take doc gave me prescription for domperidone is this safer?

Meds: Both medications are dopamine blockers, so they are similar in pharmacological action. The most concerning side effect from both is extra pyramidal symptoms (most common is a lock jaw like syndrome). In Reglan (metoclopramide) this can happen up to 10 percent esp in people under 30. Comparisons has a 2 percent risk of this. ...Read more

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Can doctors prescribe reglan (metoclopramide) and domperidone for the purpose of lactation?

Can doctors prescribe reglan (metoclopramide) and domperidone for the purpose of lactation?

DO NOT USE!!: Reglan (metoclopramide) has a Black Box Warning from the FDA. This is only used when a drug poses serious side effects. Reglan (metoclopramide) can cause tardive dyskinesia. The internet and chat rooms are filled with discussions of supplements or medications to increase breast milk. Most don't work or are outright dangerous. It makes no sense to treat yourself AND YOUR BABY with medication for a non-illness. ...Read more

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For a year Ive had nausea after eating, diarrhoea, heartburn, indigestion, headaches, absent periods and fatigue. Not pregnant. Dr prescribed domperidone but said nothing. Had ovary scan and mild PCOS?

For a year Ive had nausea after eating, diarrhoea, heartburn, indigestion, headaches, absent periods and fatigue. Not pregnant. Dr prescribed domperidone but said nothing. Had ovary scan and mild PCOS?

Probably not related: Domperidone blocks dopamine. it can be used to treat nausea and vomiting, to increase transit of food through the stomach, and to increase lactation. Your symptoms may be due to 2 separate issues. If you have already been tried on medicines for acid and not seen improvement you should see a GI doctor. PCOS can cause irregular periods,acne,increased hair (hirutism) due to hormone imbalance. ...Read more

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Should I take reglan/domperidone for gastroparesis?

Should I take reglan/domperidone for gastroparesis?

Domperidone: "Food and Drug Administration (FDA) stresses that domperidone is not an FDA-approved drug, and that it may not be legally marketed in the US." " FDA's concern about the potential health risks associated with the use of domperidone in lactating women. These risks include cardiac arrhythmias, cardiac arrest, and sudden death." ...Read more

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Why do no PPIs work for me? Can't take domperidone/metaclopramide as cause arrithmias. Can you suggest anything else? Already had failed Nissen Fundo

Depends on dx: Domperidone and metaclopramide are pro-kinetic agents, that help stimulate stomach and intestinal motility. If you are having gastroparesis as the underlying cause of reflux, then you may also be a candidate for gastric pacemaker. This involves significant screening and testing to determine whether you would be a candidate. ...Read more

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I have had some pretty nasty heartburn with this pregnancy. I told the dr. and she prescribed reglan (metoclopramide) - anybody used this?

I have had some pretty nasty heartburn with this pregnancy. I told the dr. and she prescribed reglan (metoclopramide) - anybody used this?

Be very wary: I would not recommend Reglan (metoclopramide) in pregnancy. It has black box warnings from the FDA, with a strong recommendation for "short-term (4 to 12 weeks) therapy for adults with symptomatic, documented gastroesophageal reflux who fail to respond to conventional therapy." It is not to be used in the pediatric population. Side effects in toddlers have included severe muscle spasm. Fetal effects unknown. ...Read more

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Reasons for frequent mouth ulcer and heartburn after eating food.inspite of taking taking tablets Pantoprazole and Domperidone,giving temporary relie

2 separate problems: These 2 problems should be addressed separately. 1. Mouth ulcer also called canker sores are the most common oral lesions. Individual ulcers typically last 1-2 weeks and no treatment is needed. 2. Heartburn could be serious GI problem and should be addressed by primary care physician. Good luck. ...Read more

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Why has domperidone not been approved by the fda?

Why has domperidone not been approved by the fda?

Domperidone: " FDA's concern about the potential health risks associated with the use of domperidone in lactating women. These risks include cardiac arrhythmias, cardiac arrest, and sudden death." (https://www.nabp.net/news/domperidone-not-fda-approved-should-not-be-marketed-in-the-us-fda-stresses) ...Read more

Dr. Charles Cattano
1,435 doctors shared insights

Heartburn (Definition)

When acid and peptic juices reflux into the esophagus, one might have the sensation of burning or pain under the breast bone. It can radiate up to the throat and down to the region of the solar plexus. Some may describe it as bad 'indigestion' and others may feel like they are ...Read more


Dr. Angelina Postoev
1,209 doctors shared insights

Indigestion (Definition)

Indigestion is a feeling of discomfort in the upper belly (abdomen) during or right after a meal. It may present as a feeling of uncomfortable ...Read more