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Doctor insights on: Proinsulin

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Dr. John Jun
45 Doctors shared insights

Proinsulin (Overview)

Insulin is made from in beta cells of pancreas not clinically useful in vast number of situations.


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What are insulin and proinsulin?

What are insulin and proinsulin?

Sugar hormones: Insulin is a major regulator of glucose levels. Insulin promotes the uptake of glucose, particularly by muscle and fat cells. This is why we use Insulin therapy in diabetes, as an Insulin injection will force glucose levels to fall. ProInsulin is a precursor of the Insulin molecule as it is being produced in the pancreas. Small amounts of proInsulin are detectable in the blood in this way. ...Read more

Dr. John Jun
45 Doctors shared insights

Proinsulin (Overview)

Insulin is made from in beta cells of pancreas not clinically useful in vast number of situations.


2

2
Cause of elevations in proinsulin, c-peptides and proinsulin:c-peptide ratio, c reactive protein & ferritin. Normal A1c & glucose. Previously overwei?

Cause of elevations in proinsulin, c-peptides and proinsulin:c-peptide ratio, c reactive protein & ferritin. Normal A1c & glucose. Previously overwei?

Can't answer: Nobody here can answer without your clinical history, though I wouldn't be surprised if you have hemochromatosis -- truth is, I hope you do, because it's the easiest of all the deadly diseases to manage. It's also worth remembering that serum ferritin is an acute phase reactant and likely to be high during some other illness. You're a person, not a set of labs. Insist on a full explanation. ...Read more

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What is the definition or description of: proinsulin?

What is the definition or description of: proinsulin?

Molecule from which.: Insulin is made from in beta cells of pancreas not clinically useful in vast number of situations. ...Read more

4

4
What are insulin and proinsulin?

Sugar hormones: Insulin is a major regulator of glucose levels. Insulin promotes the uptake of glucose, particularly by muscle and fat cells. This is why we use Insulin therapy in diabetes, as an Insulin injection will force glucose levels to fall. ProInsulin is a precursor of the Insulin molecule as it is being produced in the pancreas. Small amounts of proInsulin are detectable in the blood in this way. ...Read more

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7
Cause of elevations in proinsulin, c-peptides and proinsulin:c-peptide ratio, c reactive protein & ferritin. Normal A1c & glucose. Previously overwei?

Can't answer: Nobody here can answer without your clinical history, though I wouldn't be surprised if you have hemochromatosis -- truth is, I hope you do, because it's the easiest of all the deadly diseases to manage. It's also worth remembering that serum ferritin is an acute phase reactant and likely to be high during some other illness. You're a person, not a set of labs. Insist on a full explanation. ...Read more

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