Doctor insights on:
Progressive Systemic Sclerosis Involving Esophagus
Biopsy, blood: In advanced stages, no test is required. It if the diagnosis is suspected early, a skin biopsy will usually prove the diagnosis. In the blood, the scl-70 and the anti-centromere antibody tests are the most helpful. Other tests may be positive. The above two blood tests often help differentiate the disease from other conditions. Other tests are used to evaluate but not diagnose the condition. ...Read more
Not really: D-penicillamine might work, and there a number of studies suggesting this, but no long term double blind studies exist. A recent report suugest that a drug CellCept (mycophenolate mofetil) might be of value, and there are those that use mtx or tetracyclines.The major advances are ability to control BP and treat pulmonary hypertension. We can deal with esophgeal spasm and reflux. Nothing great at present for underlying dx. ...Read more
Timely help is key: Systemic sclerosis remains a challenging disease in the field of rheumatology where struggle for a cure or even targeted therapy is ongoing. Most patients donot have adverse outcome but in case of lung and kidney involvement prognosis can be poor. There are many other areas of the body affected by it but they don't seem to be dangerous rather patient lifestyle and medication can help. ...Read moreSee 1 more doctor answer
Do you ever diagnose systemic sclerosis sine scleroderma and if so, what are the the clinical signs and symptoms of this disease?
Extremely rare: Systemic sclerosis sine scleroderma is a fibrosing condition of the internal organs including the GI tract, pulmonary artery, and lungs, but lacking the skin features if scleroderma. Systemic sclerosis is a rare condition to begin with, and systemic sclerosis sine scleroderma accounts for <10% of patients. Diagnosis might include antibody tests or abnormal biopsy of affected internal tissues. ...Read moreSee 1 more doctor answer
I am a 20 year old female with systemic sclerosis. I have a pain in the left side of my chest which has got worse over the past couple of weeks.
Raynaud's : Raynaud's 1st but other systems can be involved - skin tightening, each person is different and on occasion the skin can be normal. ...Read more
Raynaud's: Tight skin is characteristic but there can be a variety of other symptoms such as raynaud's whihc is usually the first symptom, shortness of breath, chest pain, trouble swallowing, other GI symptoms, etc. Each person with scleroderma has a different set of symptoms and different type of scleroderma involvement. ...Read moreSee 2 more doctor answers
Much research,but: D-penicillamine might work, and there a number of studies suggesting this, but no long term double blind studies exist. A recent report suugest that a drug CellCept (mycophenolate mofetil) might be of value, and there are those that use mtx or tetracyclines.The major advances are ability to control BP and treat pulmonary hypertension. We can deal with esophgeal spasm and reflux. Nothing great at present for underlying dx. ...Read more
I have systemic sclerosis I have just come back from Spain and have swollen feet and ankles and a red rash on both shins and really swollen watery eye?
Be checked if...: Your briefed report suggests you have a long-term chronic health issue. Hence, make a follow-up appointment with the existing doctor soon. If the symptoms significantly differ from what you used to have or become unbearable, visit ER/urgent care. To put all the related things for good care together correctly, follow instructions in articles listed in http://formefirst.com/onDealSickness.html. ...Read more
What other conditions could 'focal dermal sclerosis' with telangiectasia on a skin biopsy indicate besides scleroderma?
I have dysmotility of esophagus and GERD 3mmhg (scleroderma). Will be posibble to do fundoplication in the future if my esophagus will be ok? Thanks
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