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Doctor insights on: Progressive Supranuclear Palsy Neurologic Problems

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Is possible for progressive supranuclear palsy to be cured / get better?

Is possible for progressive supranuclear palsy to be cured / get better?

Good Rx, but no cure: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile. ...Read more

Palsy (Definition)

...is a corruption of French "paralise" from Latinized Greek "paralysis." In the old days it meant any kind of persistent weakness. To this day Parkinson's disease is also called "paralysis agitans" which is a Latin translation of Dr. Parkinson's original name for it, the "shaking palsy." We've obviously reborrowed the full form "paralysis" into English as well; today ...Read more


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Help plz! Can progressive supranuclear palsy occur in children or teenagers?

Help plz! Can progressive supranuclear palsy occur in children or teenagers?

Very unlikely: From the Mayo clinic, progressive supranuclear palsy "typically affects people around the age of 60, and is virtually unknown in people under the age of 40." http://www.mayoclinic.org/diseases-conditions/progressive-supranuclear-palsy/basics/definition/CON-20029502?p=1 ...Read more

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Is it possible for anesthesia cause progressive supranuclear palsy (psp)?

Is it possible for anesthesia cause progressive supranuclear palsy (psp)?

Unlikely: Though anesthetics do have an effect on the brain, it is unlikely that they would cause this problem. The anesthetics that we use can decrease blood flow to certain areas of the brain, so they might unmask a pre-existing psp, but again that is speculation. I would talk to your neurologist about this problem. ...Read more

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What are the treatments for progressive supranuclear palsy?

What are the treatments for progressive supranuclear palsy?

Good Rx available!!: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile. ...Read more

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I was diagnosed with progressive supranuclear palsy 5 years ago. Are there any good clinical trials available for psp?

Try this: Psp is frustrating and unfortnately progressive. Also, there just aren't many doctors with a ton of experience with this "rare" condition. See: http://www.Pspinformation.Com/ you may be able to find what you are looking for, or at least get connected to a support network. ...Read more

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I have progressive supranuclear palsy. My biggest issue is that my eyelids are hard to open (90% of the time). Are there any good solutions for this?

Some to try...: Visual problems are common complaints with psp. Sometimes this is due to spasms of the muscles causing the eyes to stay closed. Other times the eyes involuntarily point down or don't line up together. Treatment is difficult, but options for are available to try. See http://www.Pspinformation.Com/disease/psp/psp-eyesight.Shtml. ...Read more

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What can cause progressive supranuclear palsy?

What can cause progressive supranuclear palsy?

Tau protein D/O: No, tau protein deposits & neurofibrillary tangles in neurons cause the death of these cells. Because they are in some similar areas as parkinson's disease, psp can appear similar clinically, but there are clear differences. Treatment approaches are roughly the same with different areas needing most attention. Primarily balance/falls/injury, did inhibiting dementia & dysphagia/aspiration. ...Read more

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How can you treat progressive supranuclear palsy?

How can you treat progressive supranuclear palsy?

Good Rx Available!!!: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile. ...Read more

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What are the symptoms that characterize progressive supranuclear palsy?

What are the symptoms that characterize progressive supranuclear palsy?

Brain studies: This is a term reserved for conditions that affect the connection between nuclei controlling the eye movements with the centers in the brain usually in the frontal lobes. Inability to look up is a common finding. ...Read more

Dr. Justin ORourke
29 doctors shared insights

Supranuclear Palsy (Definition)

Supranuclear palsy is a rare brain condition that causes serious problems with walking, eye movements, and balance. The disorder develops slowly over time as the cells in parts of the brain that control movement are destroyed. Although there is no cure, there are ways ...Read more


Dr. Robert Hutchman
35 doctors shared insights

Progressive Supranuclear Palsy (Definition)

Progressive supranuclear palsy is a rare condition in which a person has a degenerative brain disease that damages nerve cells in the parts of the brain that control eye movements, breathing, swallowing, speech, ...Read more