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Doctor insights on: Progesterone Topical Cream Interactions

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Is bioidentical progesterone topical cream for arms just as good as taking a 50 mg bioidentical capsule at night before bed for menopause hot flashes?

Is bioidentical progesterone topical cream for arms just as good as taking a 50 mg bioidentical capsule at night before bed for menopause hot flashes?

Neither: The term "bioidentical" is a marketing tool, used to make people believe that these products are somehow better or safer than other forms of hormones. There is no good evidence that this is true. Most topical creams are not regulated by the fda, and so their effectiveness is mostly unknown. Estrogen is the much more effective hormone for treating menopausal symptoms than progesterone. ...Read more

Dr. Seth Derman
1,129 doctors shared insights

Progesterone (Definition)

Progesterone has been found to be helpful in preventing preterm birth in a patient who has a history of delivering babies too early. It can be given as vaginal suppositories. It is most often given as weekly ...Read more


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I just started using a natural progesterone cream. Is there any interaction taking an occasional Xanax (alprazolam) along with the cream?

I just started using a natural progesterone cream. Is there any interaction taking an occasional Xanax (alprazolam) along  with the cream?

No: There are no known interactions between the two. However if more than 'occasional, ' xanax (alprazolam) is not the greatest treatment for anxiety. In addition, if both drugs are prescribed, your pharmacy will automatically check all your prescriptions against each other for interactions and let you know before you even take one. If one is not prescribed, you shouldn't be taking it. Talk to your doctor. ...Read more

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Where can I buy progesterone cream?

Where can I buy progesterone cream?

A pharmacy: With a prescription, you can buy it at most pharmacies. If you don't have a prescription and need one, you can see your doctor or call Health-Tap Concierge. You can chat, or do a video consult with a doctor in your state who can prescribe you progesterone cream if appropriate. Or you can drive to Mexico and buy it in a Mexican Pharmacy without a prescription. Best wishes! ...Read more

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Are there side effects of progesterone cream?

Are there side effects of progesterone cream?

Usually not: A short answer is 'few to none.' it may depend on what cream you use, where you use/apply it, how often, and for what purpose. Progesterone creams used intravaginallyfor women sometimes give mild itching or irritation, the gels also may 'clump' and give discharge. On the skin, irritation sometimes occurs. There are no medically important risks or major side effects to these creams. ...Read more

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What are the risks of using progesterone cream?

What are the risks of using progesterone cream?

Not absorbed: Progesterone cream is not very well absorbed from the skin. Therefore, you have no way of knowing how it affects your body. It is not recommended. ...Read more

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Are there any side effects of overdosing on progesterone cream?

Are there any side effects of overdosing on progesterone cream?

Not really: First of all, it is very hard to overdose on the cream and secondly Progesterone is very bening. However, if one uses it inapropriately in terms of timing it can alter cycles and make timing very confusing. ...Read more

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Need to take progesterone cream. Are there dangerous side effects?

No!: Progesterone creams used intravaginally for women sometimes give mild itching or irritation, the gels also may 'clump' and give discharge. On the skin, irritation sometimes occurs. There are no medically important risks or major side effects to these creams! ...Read more

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What is the best way to reverse side effects of natural progesterone cream?

What is the best way to reverse side effects of natural progesterone cream?

Lower the dose: During the normal menstrual cycle, Progesterone levels vary greatly. Thus, for many women who use Progesterone the dose has to vary depending on estrogen levels and other factors. For adjustments, cream rather than capsules allow for better regulation of dose. Generally start with a low dose such as 1/8 teaspoon of Progesterone cream. And work up slowly. ...Read more

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I am 30 years old and im not going thru menopause, can I use a progesterone cream ?

Yes: Especially if you have irregular or anovulatory cycles. A quality Progesterone appropriately used may be of benefit. ...Read more

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