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Doctor insights on: Progesterone Suppositories Side Effects

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Dr. Seth Derman
1,132 doctors shared insights

Progesterone (Definition)

Progesterone has been found to be helpful in preventing preterm birth in a patient who has a history of delivering babies too early. It can be given as vaginal suppositories. It is most often given as weekly ...Read more


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Accidentally i left my progesterone suppositories out of the refridgerator for 12 hours. They did not melt. Are they no more useful?

Accidentally i left my progesterone suppositories out of the refridgerator for 12 hours. They did not melt. Are they no more useful?

Should be fine: Being left out at room temperture (68-75 deg F ) should not make them ineffective. Just put them back in the refrigerator for 20-30 minutes and then insert one of them vaginally as directed. ...Read more

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Am on progesterone suppository.Is there any way to find placenta has taken over progesterone production at 12 wks before stopping suppository?

Am on progesterone suppository.Is there any way to find placenta has taken over progesterone production at 12 wks before stopping suppository?

Luteal phase defect: I use progesterone in the 1st trimester quite a bit for borderline progesterones and luteal phase defect. I don't check the levels after 12 weeks because the placenta produces a sufficient amount and losses from low progesterone occur much earlier. Certainly a progesterone can be done once off the suppositories, but while you're taking them the level in your blood will reflect total progesteron ...Read more

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I was just put on progesterone suppositories at 7weeks my level was 10 and I'm on 40mg 2times a day. Is that a good mg or should I be getting more?

Progesterone (PG): Check with your OB if you haven't done so already about when she plans to re-check your progesterone levels. She can tell you what PG levels are ideal and if you need to adjust the dose. ...Read more

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Does progesterone suppositories cause brown discharge ? I'm 5weeks 4days btw

Not really: It's common to have some brown spotting early in pregnancy. It is not caused by the Progesterone though. An ultrasound in a week or so should be able to see if you have a viable embryo. In the meantime, you should continue the Progesterone as directed by your doctor. And call the doctor if you have any bright red bleeding! ...Read more

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We had our IUI on 23rd July can we start progesterone suppositories? what will be its benefit.

We had our IUI on 23rd July can we start progesterone suppositories? what will be its benefit.

Talk to yor doctor: The physician who performed your IUI will make those recommendations and should be able to describe to you the risks, benefits, and side effects. ...Read more

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Can u have sex while on progesterone suppositories 200mg x2 a day?

Can u have sex while on progesterone  suppositories 200mg x2 a day?

Yes: It is ok to continue to have relations while using the vaginal medication. You should just wait to place the suppository until after you have had sex. ...Read more

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