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Doctor insights on: Prochlorperazine Edisylate Medication

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For GI issues. Taking Ranitidine, Carafate, Compazine, (prochlorperazine) and GasX... any contradictions interactions to watch out for? Medications by primary dr. And Gastroenterology dr.

For GI issues. Taking Ranitidine, Carafate, Compazine, (prochlorperazine) and GasX... any contradictions interactions to watch out for? Medications by primary dr. And Gastroenterology dr.

Ok: These medications all have different mechanisms of action and I don't think there are contraindications or interactions to worry about. In situations or questions like this, your pharmacist, who has access to information about almost all medications, can be very helpful. ...Read more

Dr. Ira Friedlander
52 Doctors shared insights

Prochlorperazine (Definition)

Prochlorperazine is an inotrope which is a kind of heart ...Read more


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If I am allergic to compazine, (prochlorperazine) are there other drugs I should avoid?

If I am allergic to compazine, (prochlorperazine) are there other drugs I should avoid?

Some similar drugs: Prochlorperazine (compazine) is a phenothiazine type of drug. Other phenothiazine drugs include: Promethazine (phenergan), Chlorpromazine (thorazine), Fluphenazine (prolixin), trifluoperazine (stelazine), etc... A person allergic to Compazine (prochlorperazine) may choose to avoid other drugs of the same type, but it is hard to predict which similar drug he will react to. ...Read more

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If I am allergic to Compazine (prochlorperazine) (tongue swelled up 26 years ago!), is it safe to take Hydroxyzine? Always told to be aware of "zine" drugs.

They are not close: In this case, the name does NOT tell you much about the chemical structure of the drug and these two are not very similar and do NOT generally cross react at all.
Without an actual examination, I cannot give specific medical advice on your particular health, and you could have reactions to more than one drug regardless of which two drugs we choose, but these two drugs aren't closely related. ...Read more

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How are antipsychaotic drugs like compazine (prochlorperazine) used for sedation and psychosis when they cause akithesia and dystonia? I've seen it make people crazier

How are antipsychaotic drugs like compazine (prochlorperazine) used for sedation and psychosis when they cause akithesia and dystonia? I've seen it make people crazier

Antipsychotics: Every medication has side-effects, and antipsychotics are no exception. If used cautiously ; with clear indications ; close monitoring, they are for the most part safe. ...Read more

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17 yrs old was prescribed compazine (prochlorperazine) by gp had stomach ach I read that it's a anti psychotic drug effecting dopamine, does that create permanent chgs?

17 yrs old was prescribed compazine (prochlorperazine) by gp had stomach ach I read that it's a anti psychotic drug effecting dopamine, does that create permanent chgs?

Antiemetic: Used safely for yrs to alleviate nausea ; vomiting oral im ; suppository routes usually only a few doses--shouldn't cause any lasting harm. ...Read more

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Does prochlorperazine help with anxiety?

Does prochlorperazine help with anxiety?

Yes,: It can help in the short term. But side effects limit its' use over the long term. ...Read more

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Negative side-effects with compazine (prochlorperazine)?

Negative side-effects with compazine (prochlorperazine)?

Compazine (prochlorperazine): Side effects of Compazine (prochlorperazine) can be serious and are related to the compound itself, which is a mild anti-psychotic drug with structure similar to other older antiphyschotics. Serious effects can involve spastic movement, temperature increase and muscle breakdown with high fever that is life threatening in rare cases. More common is spastic movements called extra-pyramidal effects, disjointed mvmt. ...Read more

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Proper amount of compazine (prochlorperazine) per month for migraines?

MIGRAINE AND VOMITIN: Compazine (prochlorperazine) can help to treat nausea and vomiting which are associated with migraine.
The recommended adult dose is 5-10 mg orally every 6-8 hrs as needed not round clock.
It is not advised to take it very frequently as any medication has adverse effects, Compazine (prochlorperazine) may leads to side effects as it decreases the Dopamine in the body. ...Read more

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Are prochlorperazine and procyclidine the same thing?

Procyclidine/Prochlo: Prochlorperazine (Compazine) is for treating nausea/vomiting. Procyclidine (Kemadrin) is for treating side-effects of Antipsychotics. ...Read more

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Is is ok to drink alcohol whilst taking prochlorperazine?

Is is ok to drink alcohol whilst taking prochlorperazine?

Alcohol and Nausea: Nope. Alcohol is very hard on the stomach. Taking a medication to calm the stomach while drinking alcohol that is harsh on the stomach makes no sense. ...Read more

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How long does prochlorperazine take to work for dissness?

How long does prochlorperazine take to work for dissness?

Oral or IV or IM: If you are taking it for vertigo and IF it is going to work should take effect in 20-30 minutes orally or by dissolving tablet in your mouth but a bit quicker for IV and variable for IM. 2 issues; do you rally have vertigo or is it another problem? Even if you have true vertigo it may not work. If not improving see your doctor. ...Read more

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Can u take compazine (prochlorperazine) and resteril together? Thank you

Yes, cautiously: Caution is advised. The combination may increase the risk of sedation and psychomotor impairment ...Read more

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How long does it take for compazine (prochlorperazine) to clear from the body?

It depends...: It depends on if you've taken a single dose or multiple doses. For a single dose it should be gone within 30-50 hours. For multiple doses it should be gone within 70-110 hours from your last dose. However the effects of any dose should last no longer than 3-4 hours. ...Read more

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Does compazine (prochlorperazine) help anxiety?

Compazine (prochlorperazine): Nope. This drug is used to help alleviate nausea. ...Read more

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Can you take atorvastatin 40mg and prochlorperazine 5mg together?

Can you take atorvastatin 40mg and prochlorperazine 5mg together?

Yes: According to Epocrates my subscription drug app. There is no interaction between these 2 drugs. However
I added your other listed drugs. There are interactions btw Norco and Tylenol; Compazine (prochlorperazine) and Norco. Contact your pharmacist and Doctor to discuss the risks benefits of taking all of these drugs together at once. ...Read more

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What happens if you take percocet with compazine (prochlorperazine)?

Sedation and more: These medications should only be taken together if specifically directed by your physician. The combination will be more sedating and constipating. There are reports of low blood pressure.
Only take these if your physician directed you to do so and follow up with her/him if you have any issues. ...Read more

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How long after taking 10mg of metoprolol can I take 10mg of prochlorperazine?

How long after taking 10mg of metoprolol can I take 10mg of prochlorperazine?

Drug interaction: The two drugs that you mention are noted to have a drug interaction in that they might cause your blood pressure to drop even further. All drug interactions are not necessarily bad and they will not necessarily happen in you. It has been noted. ...Read more

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Likelihood of developing more serious effects from compazine (prochlorperazine) (NMS, kidney function etc) from a sing 5 mg dose?

Very unlikely: Compazine (prochlorperazine) is a very routinely used medication with an overall safe adverse effect profile. It would be incredibly rare to see more serious adverse effects like NMS from a single low dose of 5 mg. ...Read more

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Can I take antivert if I'm allergic to compazine (prochlorperazine)?

Can I take antivert if I'm allergic to compazine (prochlorperazine)?

Yes: They are in different drug classes and should not cross react. However they are not usually given for the same indication. If you are looking for a good substitute for nausea a better choice would be zofran and/ or possibly dramamine. Phenergan (promethazine) is very sedating and may not be tolerated but is also a possibility if looking for nausea solution. Antivert is acceptable. ...Read more

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If I'm allergic to compazine (prochlorperazine) can I take Dramamine?

Allergy: Please contact your primary doctor about this. If you are allergic to compazine (prochlorperazine) please stop taking it and listen to your doctor's advice.

Hope all goes well. ...Read more

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How long for 5mg of compazine (prochlorperazine) to leave system? Had for migrain cocktail, feeling restless/anxious!

Liver/kidney at work: This medication has to be metabolized in the liver, and there are both biliary and kidney elimination routes, after liver clearance. Therefore, it might take 8 hours or longer. However, side effects might clear when blood level is gradually lower. ...Read more

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Which causes more drowsiness - compazine (prochlorperazine) or zofran?

Which causes more drowsiness - compazine (prochlorperazine) or zofran?

Compazine (prochlorperazine) does...: Ondansetron (zofran), a powerful anti-nausea drug, is a serotonin 5-ht3 receptor antagonist. It blocks these "receptors" linked to the crtz. The "vomiting center" located in our brains. Compared to compazine, (prochlorperazine) a piperazine phenothiazine linked to other brain receptors (d2), it causes very little sedation. Both are used to decrease nausea and vomiting after surgery. ...Read more

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What could be the affects of an overdose from propranolol, naproxen, prochlorperazine and ibuprofen?

What could be the affects of an overdose from propranolol, naproxen, prochlorperazine and ibuprofen?

Overdose of meds: There are a great many possibilities. You should report this matter to your doctor so that you could be examined and treated as necessary. ...Read more

Compazine (Definition)

Prochlorperazine is an inotrope which is a kind of heart ...Read more


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