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Doctor insights on: Pristiq Withdrawal

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How long can pristiq (desvenlafaxine) withdrawals last?

How long can pristiq (desvenlafaxine) withdrawals last?

Pristiq (desvenlafaxine): Depends on the dose & length of time u have been on it, & if replaced by other antidepressants, usually within first week or 2 ...Read more

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What are symptoms of pristiq (desvenlafaxine) withdrawal?

See your doctor: The question is why you ask this ap question. You should discuss with your prescribing doctor before stopping the medication and can help you with a taper schedule if necessary. Anxiety, irritability, and recurrent depression may occur with abrupt withdrawal. ...Read more

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How long do withdrawal effects from pristiq (desvenlafaxine) last?

Depends: The flulike muscle aches and irritability may last a week or two, but a transient increase in anxiety or a dip in your mood may last for several weeks or a month or so. ...Read more

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How can I handle severe withdrawal symptoms from pristiq (desvenlafaxine)?

Taper slowly: You should reduce the dose slowly. Decrease by 1/4 of your dose weekly. ...Read more

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Can i take Zoloft to help withdrawal symptoms from pristiq (desvenlafaxine) until i can get the pristiq (desvenlafaxine) filled tomorrow?

Can i take Zoloft to help withdrawal symptoms from pristiq (desvenlafaxine) until i can get the pristiq (desvenlafaxine) filled tomorrow?

Not generally: a good idea to take Depression medicines intermittently or as needed. Not sure if it will help. Zoloft is quite different than Pristiq (desvenlafaxine) and may cause unwanted side effects even if taken for only 1 or 2 days. You may try any over the counter headache / nausea med which are the main side effects of "withdrawal". Maybe a Physician from your State is available on HeathTaP Prime to refill today? ...Read more

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If you are a rapid metabolizer and you get interdose withdrawal daily, is Pristiq (desvenlafaxine) the ideal antidepressant, since it bypasses the liver?

If you are a rapid metabolizer and you get interdose withdrawal daily, is Pristiq (desvenlafaxine) the ideal antidepressant, since it bypasses the liver?

Not necessarily: About 45% of Pristiq (desvenlafaxine) is excreted unmetabolized by 72 hours post dose. The rest is metabolized by CYP3A4 which is a liver enzyme. It does avoid CYP2D6 which is the most common enzyme which metabolizes psychiatric medications. I assume you mean that you are a rapid metabolizer of the 2D6 enzyme. In that case, Pristiq (desvenlafaxine) may be a reasonable choice. ...Read more

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My dr took me off Pristiq and put me on Prozac to help taper down, however, I've still had awful withdrawals- increased anxiety, paranoia, "brain zaps", amplified negative feelings, etc. Is there a point I should be "concerned" enough to seek medical care

Talk to doctor: In my practice, with my patients, I have never taken a patient off Pristiq (desvenlafaxine) cold turkey. I always recommend tapering down gently, to avoid the withdrawal symptoms you describe. Talk to your treating physician about restarting the Pristiq (desvenlafaxine) and tapering. ...Read more

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