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Doctor insights on: Prion Diseases In Children

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Describe prion diseases?

Describe prion diseases?

Rare diseases: Prion diseases are rare disorders that the effected and transmitted by misfolded proteins. Read the site below for more information.
http://ghr. Nlm. Nih. Gov/condition/prion-disease. ...Read more

Dr. Thomas Montine
76 Doctors shared insights

Prion Diseases (Definition)

An infection agent consisting only of protein. They behave in very much as slow viral infections do clinically. Many are neurodegenerative; think mad cow disease, ...Read more


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How common are prion diseases?

How common are prion diseases?

Not very: Hi, the most common prion disease is CJD, with a uniform incidence of approximately 1 case per million population both in the United States and internationally. Familial forms of prion diseases, such as GSS and fatal familial insomnia (FFI), are much more rare. About 10% of cases of CJD are familial, with an autosomal dominant pattern of inheritance linked to mutations in the PRNP gene. ...Read more

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What is the definition or description of: Prion diseases?

What is the definition or description of: Prion diseases?

Prion: An infection agent consisting only of protein. They behave in very much as slow viral infections do clinically. Many are neurodegenerative; think mad cow disease, scapie, there are others. ...Read more

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Can you get a prion diseases from gm food?

Can you get a prion diseases from gm food?

No: There is no evidence--nor reason to think--that gm food should or could generate or increase infectious prions. Without comment on whether gm foods are a boon or a bane, the only way I could imagine this happening would be if some evil scientists deliberately created a gm food to generate bad prions in order to eliminate their own financial base ;). ...Read more

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Are the prion diseases going to ever cause a pandemic?

Are the prion diseases going to ever cause a pandemic?

Never say never: Not something I would lose sleep over as a citizen; something I would pay a lot of attention to as as beef inspector. So far, safeguards seem solid. Yet, 1/3 of the wild elk population in the us west is "infected" with prion disease, without illness. Is this a problem, or normal nature? Prudence says pay attention, but don't panic. ...Read more

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Can you get prion diseases by eating anything other than brains?

Can you get prion diseases by eating anything other than brains?

Yes: Infectious types of prions have even been found in muscle tissue. But it's not that they could concentrate there adequately to cause infection. The entire biosphere has a substratum of prions with which all biological systems are in equilibrium. For infection to occur, this equilibrium must be tipped adversely which is hard to do. Feeding prion infected beef back to cattle can do, or cannibalism. ...Read more

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How can prion diseases be prevented?

How can prion diseases be prevented?

There are many forms: Of Prion disease from Fatal Familial Insomnia to Kuru. Generally speaking I would avoid eating brains form any source (see my editorial in the British Medical Journal Lancet) also avoid blood products from potentially contaminated sources where there have been cases of Variant CJD (Mad cow disease). Some cases occur through spontaneous mutations, corneal transplants and contaminated allographs. ...Read more

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Why do prion diseases have such long incubation periods? Can they be stopped at all?

Why do prion diseases have such long incubation periods? Can they be stopped at all?

Supportive care only: The duration of incubation of prions is probably related to the folding state of the inoculum and the sequence of the host prion protein. At present, there is no effective treatment for prion diseases, and all are universally fatal. ...Read more

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Are prion diseases more common among people who hunt and eat what they kill? (Due to the meat not being tested for disease)

Dept of Health: Contact your local Department of Health and ask if prion disease is a problem in your region. It is unlikely it would be infecting your venison. ...Read more

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Have we gotten ahead of the game on prion diseases? Or are prion diseases likely to be major social/public health problems down the road?

Have we gotten ahead of the game on prion diseases? Or are prion diseases likely to be major social/public health problems down the road?

Hard to say: The mad cow epidemic and subsequent outbreak of vcjd was brought to the surface by feeding animal proteins to herbavores. Science has quite a lot more to learn about prions. They are likely to be involved in other processes and not all related to disease states. ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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Are neurodegenerative diseases the same as prion diseases?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
Are neurodegenerative diseases the same as prion diseases?

Prion disease: It is a rare form of Neurodegenerative disease. ...Read more

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Do all prion diseases predominately affect the brain or also the spinal cord and nerves?

Do all prion diseases predominately affect the brain or also the spinal cord and nerves?

Prion: Prions are proteins that have changed conformation, so that the normal function of the protein inside the cells won't work. The prions' also causes other normal proteins to misfold and make more prions, spreading the process. The prions affect many cells in the body, but they particularly harm nerve cells in the brain, causing progressive rapid degeneration. They are not alive, and have no dna. ...Read more

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What is a prion disease?

What is a prion disease?

Prions: Prions are a protein that is misfolded and accumulates and deposits in the body. ...Read more

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What are the symptoms of a prion disease?

Neuro: Decline in mental function, rapid over a few months. The hallmark symptom, often present, is myoclonic jerks while fully conscious. Lack of coordination is common if the cerebellum is involved. ...Read more

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What are the symptoms of a prion disease? Prion disease?

Multiple diseases: Prion diseases included a number of disorders. The most prominent, cjd, causes, dementia, ataxia, weird painful sensations, seizures, wasting etc. For more information please consult the following site.
http://www. Cdc. Gov/ncidod/dvrd/prions/. ...Read more

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What is the most common way a person gets a prion disease?

Ingestion: Current research suggests that the primary method of infection in animals is through ingestion.

Knowledge in this field is in the formative stages, and research is continuing, trying to elucidate the means of transmission.

Good news: clearly, occurrence is not common in humans; and when it occurs in animals, e.g. "mad cow disease", is isolated and eliminated, thus no spread. ...Read more

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Is altzheimer's a prion disease?

Alzheimer dementia: Can show plaques in the brain that can stain similarly to those in prion diseases but are not clearly the same sort of protein. ...Read more

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How do I make sure I never get a prion disease? Saw something about it on tv and they look horrifying

How do I make sure I never get a prion disease? Saw something about it on tv and they look horrifying

Don't think about it: Prion disease is extremely rare. Classic cases are usually genetic or having to do with cannibalism. Mad cow disease causing human prion disease is a possibility but it is not well established. One can eliminate meat from diet but there is no way to ensure you won't get it. It is out of your control so relax and don't let something like this stop you from living. ...Read more

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I'm afraid of getting a prion disease. How can I prevent this?

I'm afraid of getting a prion disease. How can I prevent this?

VERY rare: Prion disease are extremely rare Creutzfeld Jacob disease for instance has a one in million rate of occurrence Don't worry?! ...Read more