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Doctor insights on: Primary Biliary Cirrhosis Diagnostic Panel Comprehensive

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Dr. Shady Macaron Dr. Macaron
Surgery
16 years in practice
American University of Beirut Faculty of Medicine
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What is the definition or description of: primary biliary cirrhosis diagnostic panel, comprehensive?

What is the definition or description of: primary biliary cirrhosis diagnostic panel, comprehensive?

PBC: Primary biliary cirrhosis is an autoimmune disease of the liver marked by the slow progressive destruction of the small bile ducts within the liver. When these ducts are damaged, bile builds up in the liver and over time damages the tissue. This can lead to scarring, fibrosis and cirrhosis. ...Read more

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Dr. Walter Husar
1 doctor shared a insight

Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
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Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

Dr. Sidney Vinson Dr. Vinson
Internal Medicine - Gastroenterology
23 years in practice
University of Arkansas for Medical Sciences/UAMS College of Medicine
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What exactly is primary biliary cirrhosis?

What exactly is primary biliary cirrhosis?

Liver disease: Primary biliary cirrhosis is an autoimmune liver disease seen most commonly in women in the 4th to 5th decade of life. It generally presents with unexplained itching and occasionally jaundice. It is frequently found on routing screening liver tests which may show an elevated alkaline phosphotase. Though not curable it is treatable and treatment slows the progression to cirrhosis. ...Read more

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Dr. Enrique Molina Dr. Molina
Internal Medicine - Gastroenterology
31 years in practice
University of Alberta Faculty of Medicine and Dentistry
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How can I treat primary biliary cirrhosis ?

How can I treat primary biliary cirrhosis ?

Ursodiol: There is not much available to treat primary biliary cirrhosis, but ursodiol helps normalize the liver enzymes. For other therapies you should discuss with a hepatologist. ...Read more

Dr. Cosme Manzarbeitia Dr. Manzarbeitia
Surgery
35 years in practice
Universidad Mariano Galvez De Guatemala
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What is the cause of primary biliary cirrhosis?

Autoimmune: An autoimmune disorder in which the body attacks it's own liver. ...Read more

Dr. Alan Wartenberg Dr. Wartenberg
Addiction Medicine
45 years in practice
Medical College of Wisconsin
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What can be done for primary biliary cirrhosis?

Number of things: If caught early, there are medications, particularly ursodeoxycholic acid (actigall) which can slow it down. Preventing and treating complications is also important, especially high pressure in the portal vein, which can be treated with beta blockers (inderal (propranolol) and others) and sometimes surgery. Itching, fatigue and other symptoms can be treated as well, but liver transplant is needed when severe. ...Read more

Dr. Christopher Abel Dr. Abel
Pediatrics
22 years in practice
University of Texas Southwestern Medical School at Dallas
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Can you tell me about primary biliary cirrhosis?

Liver disease: Chronic disease of the liver from scarring of the biliary ducts. Probably an autoimmune disease. There are medications to help with this disease, but you need close follow up with a GI doc. Good luck. ...Read more

Dr. Richard Mangus Dr. Mangus
Surgery - Transplant
18 years in practice
Oregon Health & Science University School of Medicine
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What can I expect if I have primary biliary cirrhosis?

Maybe liver failure: Primary biliary cirrhosis is an insidious disease that tends to be progressive over time. The small ducts that drain bile from the liver will narrow and prevent adequate drainage of bile to the intestine. The liver will experience damage with years of inadequate bile drainage and eventually severe scarring (cirrhosis) occurs. With cirrhosis, the only option is liver transplantation for best chance. ...Read more

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Dr. Alan Wartenberg Dr. Wartenberg
Addiction Medicine
45 years in practice
Medical College of Wisconsin
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Has anyone survived primary biliary cirrhosis for long?

Yes: There are some new medications that have been effective for stopping the progression of primary biliary cirrhosis, particularly urso- deoxycholic acid. In addition, liver transplanation can be lifesaving, and patients can live normal lifespans after liver transplantation, although the need for anti- rejection drugs can affect the quality of life and cause complications which shorten life as well. ...Read more

Dr. Kirpal Singh Dr. Singh
Surgery
20 years in practice
State University of New York Downstate Medical Center College of Medicine
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How does one effectively treat primary biliary cirrhosis?

How does one effectively treat primary biliary cirrhosis?

Not a great answer : Unfortunately, there is no cure. The autoimmune disorder destroys the liver over time. The treatments help to relieve the symptoms (ursodiol, anti-itching meds, anti-inflammatory meds, immune suppressing meds etc.) and if the disease progresses to final stages, liver transplant is the only really treatment. ...Read more

Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
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Could i get a handicap parking placard for primary biliary cirrhosis?

Why do you ask?: These permits are placed for people who have much more physical difficulty walking than do other peoples. If you have ascites and muscle wasting from primary biliary cirrhosis, this might be fair. If you have mild disease, and people see that you are asking for a special privilege that someone else would need far more, you'll lose the respect of your peers. Make the best choice. ...Read more

Dr. Robert Rahimi Dr. Rahimi
Internal Medicine - Hepatology
5 years in practice
University of Virginia School of Medicine
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What number of years can someone live with primary biliary cirrhosis ?

Many years: Primary biliary cirrhosis (PBC) is usually diagnosed with lab tests and liver biopsy. People can live many years with PBC. Without knowing more information, I can't give you exact numbers, but hopefully you are on ursodiol medication and this helps PBC a lot. You should be following with a liver doctor who will help manage your disease. ...Read more

Dr. Arthur Heller Dr. Heller
Internal Medicine - Gastroenterology
39 years in practice
Jefferson Medical College of Thomas Jefferson University
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What differentiates primary biliary cirrhosis from other types of cirrhosis?

What differentiates primary biliary cirrhosis from other types of cirrhosis?

Location of inflam: Agree with dr. Edmisson. Pbc is autoimmune disease affecting bile ducts; can eventually lead to progressive liver disease and cirrhosis (scarring). Othe types of cirrhosis usually involve inflammation of the liver cells, due to infection (like hep b, c), toxic chemicals, metabolic disease e.g.Nonalcoholic fatty liver (seen in obesity, diabetes) iron overload, damage from alcohol, autoimmune. ...Read more

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Dr. Robert Rahimi Dr. Rahimi
Internal Medicine - Hepatology
5 years in practice
University of Virginia School of Medicine
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Help please? How many years can someone live with primary biliary cirrhosis ?

Many years: Primary biliary cirrhosis (PBC) is usually diagnosed with lab tests and liver biopsy. People can live many years with PBC. Without knowing more information, I can't give you exact numbers, but hopefully you are on ursodiol medication and this helps PBC a lot. You should be following with a liver doctor who will help manage your disease. ...Read more

Dr. Stanley Lightfoot Dr. Lightfoot
Pathology
54 years in practice
University of Michigan Medical School
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My friend as just been told she as primary biliary cirrhosis and it at the advance stage can she still live for many years?

See below: A liver transplant would be her best chance of long life. However there is a drug that a patient with this can take and it depends actually on how advacned her disease is-so her doctor should be able to help answer that. ...Read more

Dr. Stephen Cheng Dr. Cheng
Surgery - Transplant
31 years in practice
Medical College of Wisconsin
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What are early signs & symptoms of primary biliary cirrhosis?

None: Early on primary biliary cirrhosis can be associated with little or no symptoms at all, just like many chronic liver diseases. As the disease progresses, however, many people start experiencing chronic fatigue & weakness, jaundice and itching (from bilirubin build up in skin), followed by complications of cirrhosis such as ascites & malnutrition. ...Read more

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Dr. John Fung Dr. Fung
Surgery
35 years in practice
Johns Hopkins University School of Medicine
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Why do the sufferers of primary biliary-cirrhosis feel so tired all the time?

PBC = inflammation: Primary biliary cirrhosis is an autoimmune inflammatory disease, manifest by low but persistent liver damage. This causes a variety of biochemical changes which manifest by fatigue. Not all patients have fatigue, many patients are asymptomatic until the disease is advanced. Cirrhosis is also associated with fatigue. ...Read more

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Immune dysregulation: The immune system is not functioning normally in primary biliary cirrhosis. That and the chronic inflammation contrive to raise IgM. ...Read more

Dr. Gregory Sysyn Dr. Sysyn
Pediatrics
23 years in practice
Medical College of Wisconsin
19
Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
20

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How common are kayser fliescher rings in cholestasis and primary biliary cirrhosis, I have them, is it just as likely those two things as Wilson's?

Whoa: You cannot self-diagnose Kayser-Fleischer rings. Several percent of young folks have arcus lipoides, and there are other things that mimic it. They're specific for Wilson's and usually show up late, the person being quite sick already. If you think you may have cholestasis, primary biliary cirrhosis, and/or Wilson's, get with a competent gastroenterologist -- the workups are tricky. ...Read more

Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more


Dr. Bernard Seif
63 doctors shared insights

Primary Biliary Cirrhosis (Definition)

A condition where the bile ducts of the liver break down. This causes a buildup of bile in the liver, including ...Read more