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Doctor insights on: Primary Biliary Cirrhosis Diagnostic Panel Comprehensive

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What is the definition or description of: primary biliary cirrhosis diagnostic panel, comprehensive?

What is the definition or description of: primary biliary cirrhosis diagnostic panel, comprehensive?

PBC: Primary biliary cirrhosis is an autoimmune disease of the liver marked by the slow progressive destruction of the small bile ducts within the liver. When these ducts are damaged, bile builds up in the liver and over time damages the tissue. This can lead to scarring, fibrosis and cirrhosis. ...Read more

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Dr. Neigatha Graney
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Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


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Had triage sob, hepatic panel, complete blood count, hepatic profile, basic metabolic profile, liver 1, lipid profile, hemo a1c, serum-serum all done?

Had triage sob, hepatic panel, complete blood count, hepatic profile, basic metabolic profile, liver 1, lipid profile, hemo a1c, serum-serum all done?

Maybe: It seems as though you've had quite a few tests ordered. Whether or not you're done will likely depend on the reason why they were ordered along with the test results that you'll discuss with your doctor. Good luck. ...Read more

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Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Immune dysregulation: The immune system is not functioning normally in primary biliary cirrhosis. That and the chronic inflammation contrive to raise IgM. ...Read more

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Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

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Would a "basic metabolic panel" show liver problems, in non-alcoholic?

Would a "basic metabolic panel" show liver problems, in non-alcoholic?

No: It may show abnormal sodium levels but that is very non-specific. You need the liver tests which is in a comprehensive metabolic profile. ...Read more

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Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?

Both together: Neither of the tests alone tells much. A combination of tests and exams will lead to diagnosis. Pancreatic cancer is not able to be ruled out by any test or imaging study. It can only be absolutely proven by some form of biopsy. A ct guided needle or egd with brushing a may be the only way to find it. ...Read more

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Whats standard infectious workup post POTS diagnosis? Does typical workup include Lyme disease testing? ,

Whats standard infectious workup post POTS diagnosis? Does typical workup include Lyme disease testing?
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Yes: Lyme can cause autonomic dysfunction including POTS- good idea to get tested for lyme and its coinfections such as bartonella, mycoplasma, erhlichia, anaplasma, babesia and rocky mountain spotted fever which are all tick borne infections ...Read more

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Is cholestasis determined by a basic liver function panel?

Is cholestasis determined by a basic liver function panel?

History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. ...Read more

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For digestive diseases ( gastroenterolgy hepatology) ?

For digestive diseases ( gastroenterolgy hepatology) ?

Is this a question?: For diseases of these systems see a specialist if needed. ...Read more

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Which endocrine disorders/problems would a comprehensive metabolic panel blood test NOT detect?

Which endocrine disorders/problems would a comprehensive metabolic panel blood test NOT detect?

All: Comprehensive panel abnormalities could suggest possibility of endocrine disorders or in extreme hyperglycemia detect Diabetics . Thyroid disease, adrenal diseases,etc require specific test ...Read more

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Does a normal liver biopsy rule out alcoholic liver disease?

Does a normal liver biopsy rule out alcoholic liver disease?

Yes: At least at the present time. Elevated liver enzymes come and go rapidly if one is drinking intermittently. If there's any concern, or if you're generally an anxious kind of person, think about keeping your alcohol drinking to a minimum. I'm glad you are health-conscious and wish you the best. ...Read more

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Could liver function tests reveal autoimmune hepatitis?

Could liver function tests reveal autoimmune hepatitis?

Yes: Liver function tests are often elevated in autoimmune hepatitis. This is a non- specific test. If the liver function tests are elevated additional diagnostic tests will be necessary. The anti smooth muscle antibody is one of the most important in pointing to this diagnosis. Tests for other liver diseases such as hepatitis and primary biliary cirrhosis are usually part of the evaluation. ...Read more

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Is there board certification for digestive diseases ( gastroenterolgy hepatology) ?

Is there board certification for digestive diseases ( gastroenterolgy hepatology) ?

Yes: The american board of internal medicine (abim.Org) grants board certification to internists and all sub specialists through a rigorous system which requires ongoing maintenance of certification. ...Read more

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What can be done for primary biliary cirrhosis?

Number of things: If caught early, there are medications, particularly ursodeoxycholic acid (actigall) which can slow it down. Preventing and treating complications is also important, especially high pressure in the portal vein, which can be treated with beta blockers (inderal (propranolol) and others) and sometimes surgery. Itching, fatigue and other symptoms can be treated as well, but liver transplant is needed when severe. ...Read more

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For 55+ female, does early/mid stage GI issues (e.g. ulcer, tumor) get revealed by physical examination of doctor ?

For 55+ female, does early/mid stage GI issues (e.g. ulcer, tumor) get revealed by physical examination of doctor ?

Try elimination diet: Must start with your PRIMARY care doctor & if you do not have one find a good internist. Detail history will reveal many differential diagnosis. Exam alone may not reveal much but helps to rule out many options. go dairy free for 1 month except yogurt & see how your symptoms improve.If no change go grain free & see. Visit drhoffman.com for holistic & practical answers. ...Read more

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What are the minimum tests needed to diagnose biliary cirrhosis?

What are the minimum tests needed to diagnose biliary cirrhosis?

Needed tests: The major test needed are routine liver function test in combination with a test called ama and ana. If suspicioius a percutanious liver bx should be done for confirmation. ...Read more

Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more


Dr. Herman Hammerstead
64 doctors shared insights

Primary Biliary Cirrhosis (Definition)

A condition where the bile ducts of the liver break down. This causes a buildup of bile in the liver, including ...Read more