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Doctor insights on: Primary Acquired Melanosis

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What is incontinentia pigmenti - rare genetic condition?

What is incontinentia pigmenti - rare genetic condition?

Incontinentia: pigmenti is an uncommon inherited disorder of an incomplete IKBKG gene that causes increased tendency for certain body cells to self-destruct. It is more common in women and primarily affects the skin, eyes, nails and teeth. Most people are spared neurologic involvement, but delayed development, intellectual impairment and seizure may occur. ...Read more

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Anyone heard of incontinentia pigmenti a rare genetic condition?

Anyone heard of incontinentia pigmenti a rare genetic condition?

Rare X linked pbm: Ip is a rare multisystem affliction that is seen in girl infants & fatal to males in the womb. Incidence estimates run 1/40000-1-50000 births. It appears sometimes as a blistering rash, warty or just increased pigmentation in a swirling or streaking pattern. For a more see: www.Ncbi.Nlm.Nih.Gov/pmc/articles/ pmc2729954/?Tool=pmcentrez. ...Read more

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Explain the condition called a cytomegalovirus (c.M.V.) brain infection.?

Explain the condition called a cytomegalovirus (c.M.V.) brain infection.?

Cmv encephalitis: Cytomegelovirus (CMV) encephalitis in adults is uncommon. It usually is seen as part of a generalized CMV infection in immunocompromised patients. ...Read more

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Is IgG subclass 3 deficiency a primary or secondary immunodeficiency?

Is IgG subclass 3 deficiency a primary or secondary immunodeficiency?

Great question: You already know that most folks who are discovered to have real igg3 deficiency are troubled primarily by recurrent nasal sinus infections. Until we know whether there's one of more genes for this, or whether it's the result of some other change in the immune system (igg3 can drop after other illnesses), i think the mainstream medical community will remain undecided. Glad you're proactive. ...Read more

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Explain the condition called a campylobacter infection.?

Explain the condition called a campylobacter infection.?

Diarrhea: Campylobacter is a bacterial genus that includes the species "jejuni" which is one of many bacterial species that often cause acute, infectious diarrhea. It is self-limiting, rarely lasts >7-10 days, and can be treated with antibiotics but doesn't necessarily require treatment other than fluid replacement. ...Read more

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Is monogamy hereditary or an acquired trait?

Is monogamy hereditary or an acquired trait?

No definitive answer: Agree with Dr. Chen; impossible to tease apart how much is due to upbringing, life experiences (e.g., learning), or other environmental factors vs. genetics. There is some belief in the scientific community that humans evolved to be monogamous. So, genes likely influence monogamy, but humans are extremely flexible in terms of how they behave in different contexts. Hope this is helpful. Take care. ...Read more

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Explain the condition called an escherichia coli infection.?

Explain the condition called an escherichia coli infection.?

Treatable: E. Coli normally live in our large bowel and perform a useful function there. When they contaminate our food or water, disease may result. There are many subtypes of e. Coli. They are a frequent cause of "traveler's diarrhea" with nausea, diarrhea, and vomiting, but respond rapidly to even a single dose of antibiotics. Other forms produce a more serious and potentially lethal infection. ...Read more

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Primary sclerosing cholangitis - what is the inherited risk?

Primary sclerosing cholangitis - what is the inherited risk?

Very low: PSC is most commonly seen in patients with ulcerative colitis. Patients with PSC have 60-72% association with ulcerative colitis; low genetic and immunologic factors are attributed to PSC. ...Read more

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Anyone treated primary ciliary dyskinesia (pcd)?

Anyone treated primary ciliary dyskinesia (pcd)?

Pulmonologists do: Pcd is diagnosed in both children & adults & they should be followed by a pediatric or adult pulmonologist who can help monitor their lung function & provide specific therapies to prevent lung damage in the long term. Most tertiary care centers would have either an adult or pediatric pulmonologist who has expertise in the management of patients with pcd. Talk to your doctor & see a lung specialist. ...Read more

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Hi,is cryptosporidium curable or treatable

Hi,is cryptosporidium curable or treatable

TREATABLE: Most people with healthy immune system will recover without any treatment and just fluids to prevent dehydration People with weak immune system or in poor health are at risk for prolonged illness and children may have severe disease It is a treatable condition requiring hydration and in some symptomatic anti diarrheal meds are used Recurrences may happen in immune compromised patients with AIDS ...Read more

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Is primary sclerosing cholangitis rare?

Is primary sclerosing cholangitis rare?

Yes: The goal of managing acute attacks is antibiotics and IV fluids. In about 15%, emergency decompression or surgery is needed. Prevention of future attacks of cholangitis is based on removing biliary stones and debris, dilation or resection of strictures, and establishing optimal biliary drainage. Also important to rule out the clonorchis parasite. Your GI doctor can discuss newest treatments. ...Read more

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Which disease has more severe consequences dysplastic nevus or melanoma?

Which disease has more severe consequences dysplastic nevus or melanoma?

Melanoma: A dysplastic nevus, unlike a melanoma, is not a true cancer. It is best thought of as a pre-cancer, a possible precursor to melanoma that with time may possibly be able to turn into a true cancer like melanoma. ...Read more

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What are the tests for transient neonatal pustular melanosis?

What are the tests for transient neonatal pustular melanosis?

Visual Diagnosis: This benign skin condition seldom warrants any tests. A scraping of the pustules reveals white cells & eosinophils without germs.The eruption pattern & lack of inflammation separate it from other entities. ...Read more

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Can toe-walking acquired by an adult be cancerous tumor?

Can toe-walking acquired by an adult be cancerous tumor?

It could be related: Toe walking could be a result of a tumor putting pressure on the nerves or brain area that control the muscles of the foot. Consult your doctor for appropriate work-up. ...Read more

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Acquired immunodeficiency syndrome preventable yet?

Acquired immunodeficiency syndrome preventable yet?

Safe sex.: Safe sex, avoiding illicit drug use, and universal precautions for healthcare workers can prevent most cases of hiv. ...Read more

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Can Primary Acquirec Melanosis with atypia be discovered during a routine eye exam? Mine was in 2/2015, 7 months postpartum, 19 months after prior eye check at optometry office.

Can Primary Acquirec Melanosis with  atypia be discovered during a routine eye exam? Mine was in 2/2015, 7 months postpartum, 19 months after prior eye check at optometry office.

Difficult diagnosis: You should be examined by an Eye specialist (ophthalmologist) than an optometrist. Only the former can do a detailed good examination to make such a rare diagnosis. I would not trust this diagnosis coming from an optometry office. Do not sit on it too long as there is some risk of melanoma in a situation like you are faced with. ...Read more

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What is a melanosis coli?

What is a melanosis coli?

Coloration of colon: The inside lining of the colon can become darkened oftentimes from laxative use but it is a benign finding seen on colonoscopy. ...Read more

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Is melanosis a type of cancer?

Is melanosis a type of cancer?

Melanosis Coli: I think you are referring to melanosis coli. This is a discoloration of the inner lining of the colon, which is not cancerous, but can make it difficult to notice irregularities. ...Read more

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How do I cure labial melanosis?

How do I cure labial melanosis?

Dermatologist: See a dermatologist for treatment options. Bleaching treatments are available. Also discuss what may be causing the dark pigmentation such as oral contraceptives or other medications. ...Read more

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Can other medicines cause melanosis coli?

Can other medicines cause melanosis coli?

Yes: Although pathology textbooks focus on cascara laxatives as the cause of blackening of the colon mucosa by pigment in macrophages, the truth is that any laxative that works by damaging the colonic epithelium can do the same thing. ...Read more

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Can taking rifampicin cause melanosis coli?

Can taking rifampicin cause melanosis coli?

Med side effect: Doubtful. Melanosis coli is very common and can occur more frequently in females, those who use laxatives or who have inflammatory bowel disease. In general it can just happen so no need to try and see if a medication caused it. Speak to your md for more details if you are concerned but you may just "have it for no reason". ...Read more

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What exactly is melanosis cutaneous fibromatosis?

What exactly is melanosis cutaneous fibromatosis?

Disease: Depends where the lesion is. Likely it is a benign tumor (fibroma) that has skin color changes (melanosis) that need to be followed and biopsied on a regular basis. Autoimmune disease might also be a contributing factor. Ur dermatologist could best answer this. ...Read more

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What is pustular melanosis in infants and how is it treated?

What is pustular melanosis in infants and how is it treated?

Transient change: This is a transient skin condition of unknown origin.It presents in a fraction of infants with tiny blisters, pustules or open blisters with a scaley margin. The blisters or pustules are usually gone by 5 days but the pigmentary change may last for weeks to a few months. They resolve without treatment so no treatment is recommended. Exclusion of other conditions is part of the evaluation. ...Read more

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What are the tests for transient neonatal pustular melanosis?

Visual Diagnosis: This benign skin condition seldom warrants any tests. A scraping of the pustules reveals white cells & eosinophils without germs.The eruption pattern & lack of inflammation separate it from other entities. ...Read more

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Can Alli produce melanosis in the colon?

Can Alli produce melanosis in the colon?

Not usually: Melanosis coli occurs with chronic laxative use, specifically the ones that have anthraquinone to cause pigmentation in the walls. It is a benign condition. As far as i know, Alli has no empiric or theoretical reason to cause this. ...Read more

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Is there any homeopathic treatment for neurocutaneous melanosis?

Is there any homeopathic treatment for neurocutaneous melanosis?

Homeopathy: Homeopathy is an older treatment method, where small amounts of a substance that produce a symptom, are used to treat the symptom in microscopic amounts. Homeopathy is very popular in europe and is still in use all over the world. Homeopathy is symptom based and they do not "treat" named diseases. ...Read more

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Can conjunctival melanosis present with tortuous conjunctival vessels?

Can conjunctival melanosis present with tortuous conjunctival vessels?

Different things: Primary conjunctival melanosis is a brown discolored spot in the eye that resembles a freckle or somewhat scatter. It is consider precancerous. Vessels in the conjunctiva might be tortuous or not. ...Read more

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I just had a colonoscopy this morning and they found melanosis coli. I look up =abusive use with laxatives.I do not use laxatives. What else causes?

Melanosis coli: If the diagnosis is correct is caused by cascara segrada an ingredient in many over the counter laxatives, softeners and herbal remedies. It causes deposits of pigment in the mucosal cells giving a black or leopard skin appearance to the colon lining instead of the natural pink appearance, it does not pose any medical risk but it does make diagnosis of colon pathology somewhat difficult. ...Read more

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It seems I have Penile lentiginosis. I don't think it is Penile melanosis cause of my age,18, and no sexual activity. Is there any treatment possible?

It seems I have Penile lentiginosis. I don't think it is Penile melanosis cause of my age,18, and no sexual activity. Is there any treatment possible?

See a dermatologist.: A dermatologist can diagnose and treat your condition. If you are correct, and these spots are benign lentigos, topical treatments include hydroquinone, azelaic acid, corticosteroids, and tretinoin. Laser surgery can provide definitive treatment. The dermatologist can provide accurate diagnosis and definitive treatment. Take care. ...Read more

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What does ocular melanosis mean? My baby has dark spots on whites of eyes. Could it be a disease? His vision is 100% and his health is generally good

What does ocular melanosis mean? My baby has dark spots on whites of eyes. Could it be a disease? His vision is 100% and his health is generally good

Descriptive label: The label is a descriptive one meaning the eye surface contains recognized areas of melanin pigment with an unusual pattern. It is usually a benign condition and varies in frequency within several ethnic groups. About 1/20 have a risk over their lifetime of a transformation into a dangerous form of cancer. Regular checkups with an eye doc can recognize the need for treatment if it is ever needed. ...Read more

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I was told I have melanosis coli. I take daily herbal supplements to help with chronic constipation. Is this bad?

I was told I have melanosis coli. I take daily herbal supplements to help with chronic constipation. Is this bad?

Benign: Melanosis coli is a benign condition that causes yellowish discoloration of colon that occurs due to excessive use of plant based laxatives such as senna. It is not associated with any serious condition. ...Read more

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How to effectively treat ibs-c ? My colonoscopy results= two 5-10 mm benign polyps, diverticulosis and melanosis. I am a man 38 years old.

How to effectively treat ibs-c ? My colonoscopy results= two 5-10 mm benign polyps, diverticulosis and melanosis.  I am a man 38 years old.

Constipation: High-fiber diet with a lot of water every day and even prune juice may help. There are medications by prescription for chronic constipation and ibs with predominance of constipation. The polyps need to be followed depending on the pathology. Ongoing symptoms then reconsult your gastroenterologist. Read more at browardgi.Com. ...Read more

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I hav got black spot in my face.hand and neck.i mean sun exposed areas.i think its melanosis.wat should I do?

I hav got black spot in my face.hand and neck.i mean sun exposed areas.i think its melanosis.wat should I do?

Use sun screen: If the lesions are due to exposure to sun, these should be amenable to fading if you use sun screen. A wide brimmed hat and sun screen lotion on the hands and neck would be worth a try. ...Read more