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Doctor insights on: Prilosec Vs Zegerid Otc

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Dr. Tri Huynh
833 Doctors shared insights

Omeprazole (Definition)

Omeprazole is the generic equivalent of prilosec, the first oral acid-reducer agent of the proton pump inhibitor ...Read more


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Will taking an OTC medicine such as Prilosec or zegerid interfere with prescription meds such as metformin?

Will taking an OTC medicine such as Prilosec or zegerid interfere with prescription meds such as metformin?

Maybe: Otc Prilosec et. Al. Will change the acidity of the stomach. Some rx meds need the acid to be absorbed. Take the Prilosec alone at bedtime. Take any and all other meds at least 2 hours before or the next morning.

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I have g.E.R.D is it ok to take zegerid OTC longer than the 14 days?

I have g.E.R.D is it ok to take zegerid OTC longer than the 14 days?

Yes but: Otc acid reducers help reduce the discomfort of gerd. If you are not drastically better after 2 wks or your symptoms worsen during treatment, you need to see a doctor as soon as possible. Some conditions will require long term use of acid reducers but you should be under medical supervision.

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Could I be taking the wrong acid reflux medicine if I am still constantly burping and having chest pains? I have had acid reflux for over a year now and I have been taking zegerid OTC since I don't have health insurance. Recently I have been constantly bu

Could I be taking the wrong acid reflux medicine if I am still constantly burping and having chest pains? I have had acid reflux for over a year now and I have been taking zegerid OTC since I don't have health insurance. Recently I have been constantly bu

Have: Have you had an endoscopy to look at your esophagus? That sounds like very severe heartburn and you should be completely evaluated. I understand your insurance concerns, but please seek out a local clinic (there are free clinics that can often help you so ask for that). If the zegerid isn't working, then you could also add carafate (sucralfate) which works a different way (it coats the esophagus/stomach) which may help you. Also as you know, if you are overweight then losing weight will help, sleep with your head elevated, and don't smoke or drink which increases stomach acid. Please have a medical evaluation by a GI doctor as soon as you can.

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Why don't different brands of omeprazole work as well as Prilosec otc?

Why don't different brands of omeprazole work as well as Prilosec otc?

Absorption: Generic Omeprazole is the same medication as Prilosec otc. However, the formulation may result in different absorption so that the levels of medication in your bloodstream may be different. If the brand name works better for you, keep taking it.

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Is it true that prilosec otc can cause osteoporosis after a few years of use?

Highly unlikely: It is very unlikely that any of the PPIs (proton pump inhibitors) like Prilosec can cause significant osteoporosis in a short time, if at all. There is some evidence that prolonged use can increase the risk of hip fractures, but this has not been substantiated in large studies. In any event, I would still recommend going out, just the three of us.

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I'm taking 20mg pantoprazole for a long time and it is not working any longer. It was suggested I try two tablets of Prilosec OTC (40mg). I'm 120 lbs.

PPI: Both of these medications are considered proton pump inhibitors, PPI. They work by inhibiting the acid produced by the stomach and therefore decreasing the risk for developing ulcer. All of the medications are available over-the-counter at a usually lower dose. You may be able to get a prescription for a higher dose than may be cheaper.

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Prilosec otc box says to use for 14 days, then not use again for 4 months. Repeat. Most people take it everyday though. Is the "box cycle" effective?

Prilosec otc box says to use for 14 days, then not use again for 4 months. Repeat. Most people take it everyday though. Is the "box cycle" effective?

It can be: It can be, for very mild symptoms. For more persistent symptoms of reflux, a 6-week course of everyday use often results in prolonged relief that can last for months or longer afterwards. Everyday use without end is reserved for severe cases that don't resolve with initial treatment. You're correct that most people do not use this medication correctly and don't get great results accordingly.

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Will prilosec otc be just as effective if I start taking it every other day rather than everyday? Its somewhat expensive to buy and wanted to buy less

Not: Necessarily but if you follow under GERD precautions symptoms may improve. No smoking, small meals, upright during eating and at least one hour, avoid alcohol, maintain ideal weight

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Is Nexium (esomeprazole) 24 hr OTC better than Prilosec otc?

Is Nexium (esomeprazole) 24 hr OTC better than Prilosec otc?

Marketing: Nexium (esomeprazole) and Prilosec are equivalent and have the same effect. The Nexium (esomeprazole) is a molecular modification which allows the pharm company to sell the drug as a new and more effective anti-acid. In fact the effect is the same and Prilosec (generic omeprazole) is far cheaper. Save your hard earned money.

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I was on Prilosec OTC 3 months before. Can I repeat it after three months or should I change (like prevacid).

See your MD: If you are having recurrent symptoms of stomach acid or reflux, you may need a prescription medication or a consultation with a specilist for testing of your GI tract. Barrett's esophagus, a precancerous condition, can occur form continued acid reflux.

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Is that true that Prilosec OTC drug worsen gastritis and overall Heath condition with bunch if side effects? Thanks a lot

Is that true that Prilosec OTC drug worsen gastritis and overall Heath condition with bunch if side effects? Thanks a lot

No: It's job it's to make gastritis go away. I know of no known chronic condition it will make worse. If you need it take it. No one should take something they don't need.

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I'm out of my prescription omeperzole 40mg the pharmacist said I could take two 20mg Prilosec OTC at once? Would you go Along with this?

Generic: Omeprazole is just the generic name for Prilosec. If you have run out of your prescription it is very reasonable to substitute with Prilosec. And 40 mg omeprazole is equivalent to taking 2 of the 20 mg prilosec.

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Have acid reflux disease with Barrett's. My 30 mg x 2 daily lansprazole has stopped working. Can I switch to OTC Prilosec 40 mg x 2 daily and try it.

Reflux returned :/: Given your hx of Barrett's, you should schedule an appointment with your GI. S/he may need to look into why Lansoprazole stopped working. A scope may be indicated. Or s/he may increase your dose of Lansoprazole or add a second med. If Lansoprazole isn't working, it's not clear that Omeprazole would work. To avoid risk, however, the first step is to get in to your GI for an evaluation!