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Doctor insights on: Prilosec Vs Zantac For Gastritis

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Dr. Sanjay Talati
644 doctors shared insights

Ranitidine (Definition)

Treats and prevents heartburn with acid indigestion. Also treats stomach ulcers, gastroesophageal reflux disease (gerd), and conditions that cause your stomach to make too much acid (such as zollinger-ellison syndrome). This medicine ...Read more


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I just stopped Prilosec 20MG after 2 months for Gastritis. I am on Zantac (ranitidine) 300mg now but am experiencing rebound acid burning and reflux. Suggestions?

I just stopped Prilosec 20MG after 2 months for Gastritis. I am on Zantac (ranitidine) 300mg now but am experiencing rebound acid burning and reflux. Suggestions?

See your doctor to : discuss more about your diet and hydration issues too. It's important to see what's causing the rebound gastritis. Sometimes acidic foods, Tums, (calcium carbonate) calcium based foods can cause this to happen, as well as fried foods, processed foods and underlying stress and worry. There's definitely a mind- body connection with gut issues, as the microbiome controls our neurotransmitter production, absorption. ...Read more

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If its not gastritis or ulcer what can it be? Constant knawing below the breasted bone and sometimes stomach pains.Zantec and Prilosec hasn't helped

Wide Range Possible: Pains around the breast bone can be from your heart or gallbladder as well as from the stomach. I'd humbly suggest you see your pcp for a quick work up (or go to the er if pain is more severe). Heart atacks can sometimes seem like heartburn or indigestion. This would be the worst case scenario. Continued pain in this area needs to be evaluated rather urgently though, because of that fact. ...Read more

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Taking omeprazole dr 2×20 mg and ranitidine 300 mg still have chronic gastritis , sore throat too much gas with very bad smell what can it be ?

Taking omeprazole dr 2×20 mg and ranitidine 300 mg still have chronic gastritis , sore throat too much gas with very bad smell  what can it be ?

Let your doctor know: The next step is an EGD, camera to visualize esophagus, stomach and early small intesting. Be sure to avoid nsaids (ibuprofen, aspirin, Aleve, (naproxen) Advil etc.). ...Read more

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Gastritis antrum- best cure? A year of 40mg Prilosec has not worked... Ideas?

Gastritis antrum- best cure? A year of 40mg Prilosec has not worked... Ideas?

Maybe not acid...: Related. Could be irritants such as alcohol, reflux of bile into stomach, effects of aspirin, other. Talk to md about other causes and possible rx, including med change, use of other rx, e.g. Sucralfate, which works by a different mechanism than Prilosec and other ppi meds. ...Read more

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Which is better for gastritis; 150 mg of Zantac or Nexium (esomeprazole) of 40 mg?

Nexium (esomeprazole): Proton pump inhibitors (ie Nexium (esomeprazole) among others) are potent medications that nicely reduce stomach acid. H2 blocker (ie zantac) are also acid reducers but much less effective. Most patients find better relief with Nexium (esomeprazole) compared to zantac. ...Read more

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Is that true that Prilosec OTC drug worsen gastritis and overall Heath condition with bunch if side effects? Thanks a lot

No: It's job it's to make gastritis go away. I know of no known chronic condition it will make worse. If you need it take it. No one should take something they don't need. ...Read more

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Could long term use of prilosec (3yrs) be the cause of erosive gastritis? due to not having enough acid vs. to much & therefore also cause gastritis.

Could long term use of prilosec (3yrs) be the cause of erosive gastritis? due to not having enough acid vs. to much & therefore also cause gastritis.

Not likely: It is not likely that the Prilosec is associated with erosive gastritis. It is possible that a behavior,e.g. nonsteroidals, smoking, alcohol may have been continued, in spite of being on Prilosec - which was the risk factor. Prilosec, a proton pump inhibitor, is used to treat erosive gastritis, albeit at higher doses. ...Read more

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I am trying to get off prilosec.I have been taking for 10years.I have been weening with Zantac (ranitidine) which brought on anxiety.What else can I try.

Why are you on it?: Why are you on Prilosec (ppi med)? Gerd? Esophagitis? Barrett's esophagus? Ulcer? Other? Had an endoscopy? When? Following gerd recommendations, re: diet, tobacco, coffee, fatty foods, lying down, weight loss, peppermint, other meds, etc? In general, lowest dose least potent med, for shortest time to do the job is the way to go. Some people do need to be on long-term meds. Don't know if u r 1. ...Read more

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What can cause vertigo in middle of night. Started at 2am and finally subsided around 7am. I was diagnosed w gastritis about a month ago, take Zantac (ranitidine) ?

What can cause vertigo in middle of night. Started at 2am and finally subsided around 7am. I was diagnosed w gastritis about a month ago, take Zantac (ranitidine) ?

Inner ear: True vertigo is caused by an inner ear problem and usually starts quickly and ends pretty quickly the fact that this lasted several hours is a little bit more concerning and I would see your doctor.I do not think it has anything to do with your reflux ...Read more

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How far apart can I take Prilosec and zantac (ranitidine)?

A couple of hours: Prilosec should be taken 30-60 mins before a meal and zantac (ranitidine) nearly at any time. There is no major advantage in taking them both at the same time. ...Read more

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I took a 40mg prilosec, prescribed, can I take a zantac (ranitidine)? I just started the script and I need instant relief

I took a 40mg prilosec, prescribed, can I take a zantac (ranitidine)? I just started the script and I need instant relief

Not best choice: If you need instant relief you need to take something that will directly neutralize the stomach acidity, such as TUMS, (calcium carbonate) Rolaids, Mylanta etc. Prilosec(a PPI) and Zantac(H2 blocker) both act to cause the stomach to make less acid, but they don't immediately neutralize the acid already there. **PPI's like Prilosec can be "addicting" see:.. http://bit.ly/1HDj7EB ...Read more

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Prilosec didn't work for me but Zantac (ranitidine) is helping why is that???? I thought Prilosec was supposed to be better

Not really...: Like with many medications that fall within the same class or category in terms of what illness they treat, there isn't necessarily a 'better', it's more about what's better for you. Different people respond differently, so all that matters is that it's working for you. Hope that helps! ...Read more

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I take Prilosec in morning and Zantac (ranitidine) at bedtime. Zantac (ranitidine) helped at night for a while..But now it isn't. What can I do.

Increase the prilose: You may take an additional Prilosec at bedtime, or see your doctor for a rx strength medication. An antacid as an additional medication may also be helpful. If you have symptoms of relux over 2 times a week which are unrelieved with over the counter medications, (burning from acid in your esophagus) you should seeyour dr. ...Read more

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I have been taking 20 mg of Prilosec and 300mg of Zantac (ranitidine) for 3 months. The acid is still not under control should I double the prilosec?

Acid reflux: Have you modified your diet to (temporarily) eliminate food triggers like acidic foods (tomatoes, lemons, limes, oj, soda pop), caffeine, fried/fatty foods, spicy foods, onions? Is your weight under control? Do you take any meds that might trigger acid reflux: beta blockers, erythromycins, tetracyclines, etc? Have you had an upper gi/endoscopy to check for abnormalities? See doc b4 changing doses. ...Read more

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I usually take Prilosec in am and Zantac (ranitidine) 150 in pm .I ran out of prilosec. Can't buy any for a week. Can i take Zantac (ranitidine) 150 twice a day?

Best to discuss...: ...With your doctor when it comes to and individual's dose of medications. But i will tell you that zantac (ranitidine) 150mg twice a day is a common prescription dose of the medicine. ...Read more

Dr. Andrew Seibert
879 doctors shared insights

Gastritis (Definition)

Inflammation associated with mucosal injury in the stomach. Gastritis is commonly a result of infectious or autoimmune diseases, although it can also result from drugs, extreme stress ...Read more


Dr. Tri Huynh
827 doctors shared insights

Omeprazole (Definition)

Omeprazole is the generic equivalent of prilosec, the first oral acid-reducer agent of the proton pump inhibitor ...Read more