Doctor insights on:
Prilosec Develop Esophageal Cancer
If you take Prilosec more than 6-8 weeks in a row, are you more likely to develop esophageal cancer?
Esophageal cancer is cancer of the esophagus, which is a muscular tube-like structure that connects the throat to the stomach. Symptoms include difficulty swallowing, pain with swallowing, vomiting, and coughing. Long standing heartburn may lead to changes in the tissue of the esophagus that is associated with higher risk of cancer. Tobacco and alcohol ...Read more
Does taking omeprazole (40mg) every day decrease chances that Barrett's esophagus will turn into esophageal cancer? And does diet have an impact ?
Helps prevent more: For those who have Barrett’s esophagus, treatment with a high dose of a PPI might lower the risk of developing cell changes (dysplasia) that can turn into cancer. Eating a healthy diet and staying at a healthy weight are also important. A diet rich in fruits and vegetables may help protect against esophageal cancer. Obesity has been linked with esophageal cancer as well. ...Read moreSee 1 more doctor answer
Depends on the type: Squamous cell carcinoma of the esophagus for the most part is casued by smoking, consuming alcohol, nitrosamines, such as pickled foods and smoked meats. Adenocarcinoma is casued by acid reflux, which can lead to injury of the lining of the esophagus, causing barrett's metaplasia. Barrett's can lead to low grade, then high grade dysplasia, and finally esophageal adenocarcinoma. ...Read moreSee 1 more doctor answer
Several years: No lesion begins on initial transformation. There is a premalignant state where the cells appear normal and then a transformation to dysplastic cells which eventually convert to the malignant phenotype which is in-situ. Transformation to the invasive state takes a further period of months if not longer. An invasive esophageal cancer would probably take 3-5 years to evolve and become symptomatic. ...Read more
Increased risk: With barrett's esophagus, you have an increased risk of developing esophageal cancer. Therefor an individual should be in a endoscipic surveillance program. If the barrett's progresses to high grade dysplasia, then the risk of cancer is so high, then the high grade dysplasia needs to be treated either with endoscopic techniques or esophagectomy. ...Read moreSee 2 more doctor answers
What are the odds of developing esophageal cancer if I have Barrett's with no dysplasia? How often should I have endoscopy to follow up?
It is a risk factor: But odds are low. Your endoscopist knows guideline for frequency. It's also related to coverage. ...Read more
What are the chances of a 21 year old heavy drinker, and smoker having/developing esophageal cancer. ?
High, if you continu: Cancer of the mouth, throat and esophagus is very common among folks who smoke and also drink. You are basically adding two potent poisons and committing a slow suicide. It is still time to save yourself if you can taper off over a few months and then STOP them both completely in ...Read more
A 21 year old with a history of alcohol and smoking abuse. What are the chances of developing esophageal cancer at this age ?
21 years old. Everyday alcohol, ciggerete abuse for nearly 7 years. Severe acid reflux for 2 years. Could I have already developed esophageal cancer?
Need for evaluation: It is unlikely that you have esophageal cancer, but you may have ulcerations in your esophagus. Have you quit alcohol and tobacco? How much do you weigh? if you are overweight, that would make reflux worse, It would be prudent for you to consult a GI doctor for esophagitis and advice about nutrition. ...Read more
Is it possible for a cancer patient receiving chemo/ rad to develop cancer in an unrelated area? My 64 yr old father has esophageal cancer. In preparing for surgery he had a CT scan done and a 'spot' on his lung has been detected. Biopsy is scheduled, but
I : I hope your father is recovering well from his treatment and that the lung spot is nothing as many of us will have spots on ct scans. Unfortunately, however, esophageal cancer often travels (e.g. Metastasizes) to the lung. Sometimes we can help determine the need for a biopsy with a pet/ct scan which is usually part of the standard pre-surgery or pre-chemo/radiation work up for patients with esophagus cancer. The way you describe things, it sounds like the spot in the lung was found before surgery and that his doctors decided to do chemotherapy and radiation either instead of surgery or before it to try to shrink the tumor before they do an operation. If the esophagus cancer has spread to the lung, chemotherapy by itself is the best treatment. Surgery to remove the esophagus cancer is not helpful and radiation to the esophageal tumor should probably only be done if the tumor is causing symptoms that the chemotherapy is unlikely to make better on its own. In this case a short course of radiation over about 2-3 weeks would be given to try to shrink the tumor and relieve the symptoms it is causing. This is because the cancer has spread and trying to remove it from the esophagus or kill every last cell in the esophagus tumor with high-dose radiation will probably not help the patient live longer nor help him/her have a better quality of life. Therefore, if a suspicious 'spot' is found in the lung before surgery or chemotherapy and radiation, we usually biopsy it before starting treatment to make sure we don't give someone too aggressive a treatment that is unlikely to help them much. Very, very rarely, an otherwise healthy patient with esophageal cancer might have what we call "oligometastatic" disease. This means that the cancer has spread to only a few (usually 1-3) other organs or spots in the body. In this rare case, it might be reasonable to give a full course of chemotherapy and radiation to the esophagus tumor as long as the lung spot could be treated with a full dose of radiation at the same time. I've also seen patients who have unfortunately had a tumor that started in the lung (lung cancer) and one that started in the esophagus (esophageal cancer) diagnosed at the same time. In this rare case, if neither of the tumors have spread to other parts of the body, it might be reasonable to treat them both with the goal of a cure. ...Read moreSee 1 more doctor answer
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