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Doctor insights on: Prednisone Joints

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Dr. Thomas Namey
2,560 Doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


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I have ra. Weaned myself off prednisone. Having joint pain. What to do?

I have ra. Weaned myself off prednisone. Having joint pain. What to do?

See below: With ra, and in flare, you may need to be restarted on steroids again such as prednisone. Pain meds such as anti-inflammatory can help with pain in the meantime, however, you will need other meds that can acts like a maintenance medication, some are oral like methotrexate, some injectables like remicade (infliximab). A rheumatologist will need to see you for evaluation and further treatment. ...Read more

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I have had severe muscle pain and cramping throughout my body for a week. I just finished a course of prednisone for joint swelling. OTC meds aren't h?

I have had severe muscle pain and cramping throughout my body for a week. I just finished a course of prednisone for joint swelling. OTC meds aren't h?

Maybe low potassiium: We need to know the reason for the prednisone. Sometimes prednisone can change potassium or other electrolyte levels. Your physician will check some of these issues on your evaluation. If you are on a medicine for your Cholesterol this could impact this as well. This will be how your physician will evaluate these symptoms ...Read more

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How do I treat inflamed sternomanubrial joint? Prednisone is not working.

DMSO: Try DMSO (dimethylsulfoxide). DMSO (aka horse liniment) is a powerful anti-inflammatory pain reliever. It's available in health food stores and feed stores (agriculture and veterinary supplies). It's usually available as a 99% liquid, and a lower strength gel and roll-on. The liquid works well, but may be drying or irritating to some people with sensitive skin. Just apply it daily. ...Read more

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How fast oral prednisone work on joint pain?

How fast oral prednisone work on joint pain?

Usually within a day: Or earlier. But consequences and side-effects emerge with too much for too long. A quick fix, but usually not the long term one! Especially for arthritis! ...Read more

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How long does it take for prednisone to work for joint pain. I'm taking 10mg for 3 days then 20mg for the remainder of 2 weeks just started today?

How long does it take for prednisone to work for joint pain. I'm taking 10mg for 3 days then 20mg for the remainder of 2 weeks just started today?

Depends on cause: How quickly Prednisone works, if it works at all, depends on the cause of the joint pain. If you have an inflammatory arthritis like rheumatoid it may start helping within days. If you have severe bone on bone osteoarthritis it may not help at all that may only be helped with an injection into the joint. ...Read more

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If I am on 20mg prednisone daily for severe joint pain and morning stiffness should I feel 100% relief or will I still have pain? Feel slightly better

If I am on 20mg prednisone daily for severe joint pain and morning stiffness should I feel 100% relief or will I still have pain? Feel slightly better

Should help: Prednisone is a potent anti inflammatory agent. At that dose, it suggests you have inflammatory joint disease. While most pain should be improved with this dose, you may also benefit from NSAIDs as well. Discuss this with your prescribing doc. ...Read more

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Why is my SED, CRP normal even with pleurisy and swollen joints and prednisone is only thing that helps? SLE. Why does it not pick up on the inflamm?

Why is my SED, CRP normal even with pleurisy and swollen joints and prednisone is only thing that helps? SLE. Why does it not pick up on the inflamm?

No easy answer: Please forgive me. Sed rate and C-reactive protein are famously unreliable markers for inflammation in lupus and suspected lupus. A different pathway of inflammation is often involved. Despite "pop" ideas about "inflammation", inflammation enormously complicated. If it weren't, common painkillers would clear depression, which some folks describe as "a form of inflammation." ...Read more

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UCTD. MTX, celebrex, (celecoxib) plaquenil, and prednisone. After weening off prednisone I feel terrible joint and muscle pain. Any adjustments recommend to meds?

UCTD. MTX, celebrex, (celecoxib) plaquenil, and prednisone. After weening off prednisone I feel terrible joint and muscle pain. Any adjustments recommend to meds?

Tell your doctor.: You may be tapering the prednisone too quickly. Call your doctor today because you shouldn't be this miserable. Also something else could be causing your pain. ...Read more

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What causes swollen hands, feet, and ankles? Not reduced with diuretic only prednisone. Swelling inbetween finger joints not the joints themselves.

What causes swollen hands, feet, and ankles? Not reduced with diuretic only prednisone. Swelling inbetween finger joints not the joints themselves.

Inflammation: Sounds like inflammation. Must search for cause. Rule out food sensitivity. About 10 percent of population can be sensitive to nightshades, about 30-40 percent can be sensitive to gluten and casein. Other more common food sensitivities include soy, corn, beef, etc. Consider food elimination for at least 2-3 months. Leigh wagner, rd is a good dietitian who can help by phone: 913-588-6208. ...Read more

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My joints are hurting. Just the normal prednisone side effects. Will this end?

My joints are hurting. Just the normal prednisone side effects. Will this end?

May not be: This may depend on what you are being treated with and for what. We sometimes see joint complaints from tapering perdnisone. That means as the dose drops joints can hurt. This is called steroid withdrawal rheumatism. You need to discuss this with your physician ...Read more

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What can I do to stop joint pain as a side effect from prednisone?

What can I do to stop joint pain as a side effect from prednisone?

Need to know what: We need to know what type of joint pain. To some this will be counter intuitive as prednisone can help some types of joint pain. We need to know what type of health problem you are are taking prednisone for. Is the pain you have joint, or muscle? What other medical issues do you have?
Your physicians will help you clarify these issues. ...Read more

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I've got stills im 23, my joints r swollen I've been on prednisone high doses for months, I've had cort. Shots in knees, n ntfs don't work, what will help?

I've got stills im 23, my joints r swollen I've been on prednisone high doses for months, I've had cort. Shots in knees, n ntfs don't work, what will help?

Other Rx: Even though tnfs did not help, there are other biologic agents which have shown good results. One drug is Kineret (anakinra) which works on il-1 (interleukin-1) instead of tumor necrosis factor (tnf). Be sure to let your rheumatologist know that you are still in pain and that you cannot taper off the steroids. ...Read more

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I am only 125 lbs taking 20mg prednisone daily and only getting slight relief for severe joint pain morning stiffness. Normal? Making my BP high also

Unusual treatment: 26 yo female notes ineffectiveness of prednisone for widespread pain; apparently absent any specific diagnosis. This is inappropriate. An Osteopath or Rheumatologist should be consulted. Fibromyalgia might be a consideration, and a specific diagnosis is needed in order to initiate rational medical therapy. ...Read more

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I have been trying to taper off prednisone from a colitis flare up. It has been horrible and my joints have become so sore every time I hit the 10 mg?

I have been trying to taper off prednisone from a colitis flare up. It has been horrible and my joints have become so sore every time I hit the 10 mg?

Other meds?: If you have severe enough crohns disease that it requires prednisone, it is unlikely that you will be able to just taper off without the use of a steroid sparing agent such as biological agents (ie. Remicade) or immunomodulators (mercaptopurine). See your gastroenterologist or am did a referral
to an ibd subspecialist. ...Read more

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Neurosarcoidosis. Having bad joint pain for few days. First time with this symptom. On 20mg prednisone. Is it the sarcoid or the steroids? Ty

Neurosarcoidosis. Having bad joint pain for few days. First time with this symptom. On 20mg prednisone. Is it the sarcoid or the steroids? Ty

Impossible to say: It is impossible to say with knowing your complete history and doing a thorough evaluation. Ask the doctors who care for you or see a rheumatologist. ...Read more

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Dad had pmr and was on prednisone, he weaned off but 7 months later he has severe joint pains w/ no inflamitory markers all over. Prednisone effect?

Dad had pmr and was on prednisone, he weaned off but 7 months later he has severe joint pains w/ no inflamitory markers all over. Prednisone effect?

Suspect PMR relapse: It's very common to have a relapse in Polymyalgia Rheumatica.Depending on the study the average time a patient with PMR requires prednisone is 3-6 years. Although very uncommon, patients with PMR can have a normal ESR.Was a CRP done? Because patients with PMR have a dramatic response to even small doses of prednisone (15-20 mg daily) most physicians would restart prednisone and expect quick response ...Read more

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I have had itchy hives for about 6 months and drs give me prednisone and it goes away. I get joint and muscle pains with too. What could it be?

I have had itchy hives for about 6 months and drs give me prednisone and it goes away. I get joint and muscle pains with too. What could it be?

Well: If you had taken Prednisone in moderate doses for several months, then the bone pain may well be from the cortisone effect (bone loss). However it the pain occurred at the same time as the hives, I would be more concerned with an autoimmune process and would advise you to consult a rheumatologist. ...Read more

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Does a six-month regimen of prednisone (for IGA nephropathy) risk damage to hips/joints? Husband is having hip pain after a month on the drug.

Prednisone effect: One of the major side effects of Prednisone is bone loss. The importance of it depends on the underlying bone health/condition of the individual. We generally acquire a bone density scan before starting long term steroid therapy and if we find signs of underlying osteoporosis we treat it at the same time (with Calcium, Vitamin D analogs, and Bisphosphonates). Your husband probably need one now! ...Read more

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Inflamm muscles and joints."flares" throught month since 05.Dr sees no active infection (virus etc) prednisone stops sx. What else wld u test for?

Inflamm muscles and joints."flares" throught month since 05.Dr sees no active infection (virus etc) prednisone stops sx. What else wld u test for?

Autoimmune diseases: Based on your description, you might have any one or more of autoimmune diseases such as systemic lupus erythematosus, polymyalgia rheumatica, etc. You might have fibromyalgia too. You might even have viral hepatitis (B or C) or inflammatory bowel disease such as Crohn's or ulcerative colitis. Get tested for ANA, CRP.... The best thing for you to do is to see a good board-certified rheumatologist. ...Read more

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Is 700 cal per day good to loose weight? I can't do exercise due to joint pain have sle and on prednisone since 3 years.

Is 700 cal per day good to loose weight? I can't do exercise due to joint pain have sle and on prednisone since 3 years.

Starvation is bad: Starvation diets do not work. They change one's metabolism and they do not lead to any lasting weight loss. In fact they often lead to rebound weight gain.

I would not recommend any limitation of calories lower than 1200 to 1500 calories for a true diet. ...Read more

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Severe widespread joint pain/morning stiffness 9 mnth. Daily 20mg prednisone did not work, MRI of joints show no inflammation. RF DNA SM neg ANA 1:320?

Severe widespread joint pain/morning stiffness 9 mnth. Daily 20mg prednisone did not work, MRI of joints show no inflammation. RF DNA SM neg ANA 1:320?

Alternative: Despite ANA being positive, if you have no inflamm visible & prednisone had no effect, consider an alternative track: many foods cause sensitivities/joint/muscle pain without measurable inflammation.Sugar/Wheat/Gluten are among the most common. Consider seeing a doctor interested in 'Functional Medicine' & they can test for these sensitivities. Other thought: toxicities. These drs can test this, too. ...Read more

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If prednisone 20mg daily does not work is appropriate next step to start 500mg naproxen 2x daily and MRI for severe joint pain/morning stiffness?

If prednisone 20mg daily does not work is appropriate next step to start 500mg naproxen 2x daily and MRI for severe joint pain/morning stiffness?

See below: Not Really! If you're having multiple joint arthralgias a thorough workup usually is preferred with a rheumatologist and there's new medication that should control your symptoms. Good luck thank you ...Read more

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Just finished a prednisone prescription for my SI joint. The last 3 days I've had shortness of breath or heart racing. Cant relax abdominal muscles.

Just finished a prednisone prescription for my SI joint. The last 3 days I've had shortness of breath or heart racing. Cant relax abdominal muscles.

PALPITATIONS W/U: Palpitations that symptomatic deserve a prompt W/U: exam/labs especially It may be secondary to the prednisone or underlying CARDIAC ISSUE. T/EKG/Event Monitor/ECHO and The discussion of treatment options with your doctor. While you are waiting eliminate caffeine focus on staying hydrated. If palpitations worsen or syncope develops go directly to the ER. ...Read more

Dr. Stratos Christianakis
1,189 Doctors shared insights

Joints (Definition)

Joints are parts of the body, formed by the cartilage-covered ends of bones plus the strong, flexible ligaments that attach the bones to one another. Movements at the joints in the body allow the different parts of the body to move in ...Read more


Dr. John Feola
991 Doctors shared insights

Liquid Pred (Definition)

Liquid Pred is a corticosteroid which is a kind of ...Read more