Doctor insights on:
Prednisone And Humira
Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more
Yes: Cytoxan (cyclophosphamide) can be damaging both to eggs and sperm and therefore needs to be monitored closely by your rheumatologist and fertility doctor. Cytoxan (cyclophosphamide) is also considered class d in pregnancy suggesting risk of fetal harm. Long term Prednisone therapy has little effect on sperm production or ovulation. ...Read more
See details: You have asked this question before. I avoid you to avoid anabolic steroids because of the high likelihood of side effects including impotency, testicular atrophy, fits of rage and heart attacks. The use of this substance is the reason why so many professional wrestlers die so young. ...Read more
It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read moreSee 1 more doctor answer
Humira (adalimumab) every 2 weeks stopped working&got a bad psoriasis flare-up...Now on humira (adalimumab) weekly w/15mg methotrexate but still have bad psoriasis.U recommend?
Psoriasis: While Humira is an excellent therapy for severe psoriasis, there are times when it stops working. Another option for you may be stelara (ustekinumab) which is also an injectable treatment which works a little differently than does Humira and is extremely effective in many patients. ...Read moreSee 1 more doctor answer
I've been taking Methotrexate and I'm on a study drug for my Psoriatic Arthritis, I think the study drug is Humira (adalimumab), (adalimumab) can Humira (adalimumab) cause weight gain?
UCTD. MTX, celebrex, (celecoxib) plaquenil, and prednisone. After weening off prednisone I feel terrible joint and muscle pain. Any adjustments recommend to meds?
Probably OK: Both of these drugs can irritate the stomach, and together they can be a one-two punch. However, many patients do just fine especially if they did not have stomach issues to start with. Your prescribing md will be able to tell you what to watch out for. ...Read more
Yes.: My colleagues believe it is the first choice (acr and eular), but while I use it as a second or third drug, the benefit/risk ratio is incredibly good. Methotrexate has little or no justification to be taken orally though. Unpredictable absorption, stomach concenbration build up, and going to the liver on first-pass! the liver sees 600x the ultimate concentration in the blood. ...Read more
Drug interaction of humira (adalimumab) with niacin
can taking niacin affect the effectiveness of humira (adalimumab)?
No: Though interactions were reported in patients taking these two agents, Humira (adalimumab) and niacin, the patients were taking multiple other medications. It was not shown to be an interaction between the Niacin and humira (adalimumab). To test it individually, the Niacin could simply be stopped for a month assuming the Niacin was being used to treat hyperlipidemia. Ask your doctor if it is safe to hold the niacin. ...Read more
See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects. ...Read moreSee 1 more doctor answer
Rheumatoid arthritis for 7 yrs. On methotrexate & prednisone. Tried so many drugs (orencia, enbrel, (etanercept) humira...). Feeling defeated. What else can I try?
Other choices: Some older drugs such as Plaquenil may help, especially with fatigue. There are also newer drugs that act via different mechanisms such as actemra (tocilizumab). I assume the diagnosis of RA is definite. If not, retest other possibilities. An exercise program may be very beneficial, especially if you start slowly and build up with hurting yourself. Don't give up hope. You can get better. ...Read moreSee 1 more doctor answer
For rheumatologists, my mom's dr prescriped methotrexate, HQ, and prednisone plus Humira (adalimumab) q2wks for her RA..is that very strong drugs on her or normal?
"Normal" Combination: That is a reasonable combination.Get a more detailed answer ›
Currently taking humira (adalimumab) for crohns. diagnosed with dvt after foot fracture and prescribed xarelto. aren't there bleeding risks with humira (adalimumab) injections?
Better to be on methotrexate and hydroxychloroquine or methotrexate and a biologic when treating jra? Methotrexate only doesn't help
Depends on severity: Since you have already been on Methotrexate and its not helping you get complete relief from symptoms, further addition of therapies will depend on severity of your current symptoms. Hydroxychloroquine is milder in efficacy as compared to biologics & both have different side effect profiles. Talk to a rheumatologist who can assess your clinical course & treatment needs & then advise accordingly. ...Read moreSee 1 more doctor answer