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Doctor insights on: Prednisone And Depression

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Dr. Pamela Pappas
4,557 doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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Can being on Prednisone for more than a year cause depression in teens?

Can being on Prednisone for more than a year cause depression in teens?

Yes, among others: You need to talk openly w/ the Dr who prescribed to fully understand why they'd do such a risky thing. It may be the lesser of evils - but it's rarely done. If you don't get help, find another Dr ASAP - Also do NOT just stop! It MUST be tapered. Your body needs to readjust or it can fail!! Best wishes - it's important to do it right! ...Read more

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How do they reverse depression induced by prednisone? I am afraid to take the prednisone 20mg daily due to chance of a depressive state.

How do they reverse depression induced by prednisone? I am afraid to take the prednisone 20mg daily due to chance of a depressive state.

Antidepressants: If you had an steroid induced depression in the past, you may have same reactio once reexposed to prednisone. Best is to prevent it. Start taking the antidepressant that has worked for you in the pas, days prior to start taking the prednisone and keep taking it, as long and beyond the timr you are on prednisone . ...Read more

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Took 20mg of prednisone for five days. I have bipolar and it threw me into a deep depression. How long will effects last before it is out of system?

Took 20mg of prednisone for five days. I have bipolar and it threw me into a deep depression. How long will effects last before it is out of system?

As long as weeks: Unless you abruptly stop it and/or utilize appropriate medications to alleviate the depression - antipsychotics, mood stabilizers, or even brief trial of an antidepressant. Even then it may be prolonged. If you were not aware of it you may want to try any other available option in treatment in the future knowing you have this susceptibility. Also, inform your md of your reaction and diagnosis. ...Read more

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Can a low dose (5mg) of prednisone (prescribed to reduce mild adrenal hyperplasia to improve female fertility) aggravate my depression?

Can a low dose (5mg) of prednisone (prescribed to  reduce mild adrenal hyperplasia to improve female fertility) aggravate my depression?

Yes it can: Yes, Prednisone can aggravate depression. Please discuss this with your physicians. Dose adjustments may be needed in your prednisone, your antidepressants, or both. If feeling depressed but not yet being treated for depression, an evaluation could help discern what's going on. Effective treatment could be provided. ...Read more

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Is 40 MG of prednisone a day common for polymyalgia rheumatica. I'm also on antidepressant medication for major depression. I've been crying alot.

Is 40 MG of prednisone a day common for polymyalgia rheumatica. I'm also on antidepressant medication for major depression. I've been crying alot.

High dosage!: If you trust the Dr. discuss reasons and learn prognosis. If not - seek 2nd opinion! Read this link: http://www.mayoclinic.org/diseases-conditions/polymyalgia-rheumatica/basics/treatment/con-20023162 Work w/ therapist to improve mgmt of depression or again, find a more helpful one. These are hard to deal with - you want the best pros for you! ...Read more

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Taking prednisone, flovent, and nasonex: too much steroids? This caused depression? Or likely due to singulair? Dr. Prescribe lexapro (escitalopram). Good idea?

Taking prednisone, flovent, and nasonex: too much steroids? This caused depression? Or likely due to singulair?  Dr. Prescribe lexapro (escitalopram). Good idea?

A lot of med: It is not the Flovent or Nasonex (mometasone) but the oral Prednisone which is of concern. Prednisone usually makes people feel good but may induce depression in a few. Singulair rarely causes mental issues. It appears that you may have steroid-resistant asthma and i think it is time for you to consult an allergist. A drug reaction is best treated by stopping the drug and not with another drug. ...Read more

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Taken prednisone for 2 days (20 mg) and it has made me angry and depressed and awful. I'm not taking it anymore but when will it be out of my system?

Taken prednisone for 2 days (20 mg) and it has made me angry and depressed and awful. I'm not taking it anymore but when will it be out of my system?

36 hours after last : The time it takes your body to reach plasma blood levels is 2-4 hours. The time it takes your body to excrete the medication in your urine after the last dose can take anywhere from 24-36 hours. It is the best anti-inflammatory we have. Let your doctor know that you stopped it and can't tolerate it. It can affect your mood, but there may be a reason your doctor gave it to you. ...Read more

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Can prednisone and methotrexate make you depressed?

Can prednisone and methotrexate make you depressed?

Pred. can cause depr: Prednisone can cause several psychiatric manifestations-depression, psychosis etc etc oral methotrxate does not have any psychiatric side effects. ...Read more

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I took prednisone for 3 days following an allergic reaction. Is it possible to feel depressed after going off the meds? I also take lithium for mood.

I took prednisone for 3 days following an allergic reaction. Is it possible to feel depressed after going off the meds? I also take lithium for mood.

Yes: Prednisone and cortisone in general, especially in doses over 20 mg daily, often affects one's moods. Most people get "hyper" while on it then get a downer for a day or more after stopping it. A small % may actually get the opposite effects. ...Read more

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What to do when blood pressure is elivafed n humira (adalimumab) prednisone and lotabs forra feel very depressed nervous and headache

What to do when blood pressure is elivafed n humira (adalimumab) prednisone and lotabs forra      feel very depressed   nervous and headache

Talk to your doc: Humira (adalimumab) rarely has any side effects and elevated blood pressure is not one of them.Blood pressure can be raised by Prednisone but also due to pain which i assume u have if you are on lortab.You may have essential hypertension which is not due to any medication or specific illness--this should be controlled since it can lead to heart failure over years.See your doctor so u can be evaluated & treated. ...Read more

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Do I have depression?

Do I have depression?

Depression signs: Include being down most of the time, loss of interest/pleasure in activities, unintended increase/decrease in appetite/weight, sleeping more or less than usual, being agitated or lethargic, feeling worthless or inappropriately guilty or self critical, having difficulty concentrating or making decisions, ; thinking of death ; dying. Talk to your physician or a mental health professional to decide. ...Read more

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What cause depression?

What cause depression?

Causes of depression: Include a genetic component that increases your risk when a blood relative has depression, distressing experiences combined with dysfunctional negative thinking and beliefs, and behaviors that contribute to withdrawing socially & reducing pleasurable & rewarding activities. Cultivating an optimistic, resilient attitude that sees problems as solvable challenges help prevent depression. ...Read more

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What is teen depression?

What is teen depression?

Teen with depression: Depression in children & teens is much the same illness but because of age related factors expression of the depression varies. Children are especially difficult to assess due to limited understanding and communication skills. Teens bring a special set of problems to diagnosing depression; a sense of immortality, a "can do it myself" attitude, male and female hormone influences, oppositionality. ...Read more

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How to fight depression?

How to fight depression?

Task Completion: If you are able, undertake a task that you know for sure you can finish. When we complete a project, even something small like washing the dishes or organizing a closet, our brains release the same chemicals produced by the prescription antidepressants. So often, reactive depression is associated with events that take away our initiative and make us procrastinate, and this is what we must fight! ...Read more

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How to manage depression?

How to manage depression?

Depression: Depression is a serious and treatable illness. Please seek an evaluation with a mental health professional for medications and therapy for your depression. In many cases, the combination of both treatments work better than either one alone. Good luck! ...Read more

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Is depression hereditary?

Is depression hereditary?

Yes: Genetic studies have shown that risk for both major depression and bipolar disorder is inherited. Having a parent or sibling with one of these disorders increases the likelihood of developing it. I don't think this is true for postpartum depression. ...Read more

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What's mental depression?

What's mental depression?

Beyond saddnedss: Period of two weeks where one experiences depressed mood or loss of interest and at least 5 of the following: disturbances in sleep (excessive most often), apathy, withdrawal, isolation, hopelessness, thoughts of death or suicide, lack of energy, impaired concentration, lethargy. Treated best with psychotherapy in combination with antidepressants. ...Read more

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What is mixed depression?

What is mixed depression?

Bipolarity: Unipolar depression is characterized by psychomotor retardation, loss of interest in usually enjoyed activities, amotivational periods. The flip side is periods of extremely active, often extremely productive activate, as seen by such people as ted turner. If one has bipolar depression and it qis treated for what presents as unipolar depression, the manic phase can rear it's scary head. ...Read more

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Dr. Thomas Namey
2,534 doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


Dr. John Feola
965 doctors shared insights

Liquid Pred (Definition)

Liquid Pred is a corticosteroid which is a kind of ...Read more