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Doctor insights on: Precancerous Cells Vs Dysplasia

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I had a thyroid biopsy of a single nodule which shows dysplasia. Could it still be cancer if it shows precancerous cells on biopsy?

I had a thyroid biopsy of a single nodule which shows dysplasia. Could it still be cancer if it shows precancerous cells on biopsy?

It could be: Thyroid nodules are quite common. Many of them are benign but cancer is not uncommon in the thyroid gland. The needle biopsy can misread them. So the safest course is to have excision removal anytime there is suspicion like in your case: dysplasia, usually implies abnormal cells which can be cancerous. ...Read more

Precancerous (Definition)

A precancerous condition (or premalignant condition) is a generalized state associated with a significantly increased risk of cancer. If left untreated, these conditions may lead to cancer. Premalignant lesion is a morphologically altered tissue in which cancer is more likely to occur than ...Read more


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Had severe dysplasia (had leep), now breakthough bleeding. Any connection with precancerous cells of the uterus and cervical dysplasia?

Had severe dysplasia (had leep), now breakthough bleeding. Any connection with precancerous cells of the uterus and cervical dysplasia?

It is unlikely that: Your irregular bleeding is related to the leep or utrine cancer unless the leep was recently done and u r bleeding from there. Cervical cancer and uterine cancer are seperate phenomenon, though cervical cancer can extend into the uterus. Depending on age, uterine cancer is low on the list as a cause of the bleeding but see your doc if older than 35, may need endometrial biopsy just 2 b sure? ...Read more

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I was just told I had an abnormal pap test. What does it mean to have mildly abnormal dysplasia cells?

I was just told I had an abnormal pap test. What does it mean to have mildly abnormal dysplasia cells?

Common problem: Mild dysplasia is one of the first stages of abnormality to occur when a cervix is infected by hpv (human papiloma virus). This is a common probem and fortunately the body can often clear it by itself. While dysplasia can progress from mild to worse, this is easily treated and most therapy involves monitoring any changes and treating them if the get worse. Trust your OB and don't worry. ...Read more

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What does it mean to have abnormal cells on your pap smear? I was told I had dysplasia cells? Should I worry?

What does it mean to have abnormal cells on your pap smear? I was told I had dysplasia cells? Should I worry?

Follow advice: Worrying is not useful. Follow your doctor's advice for follow up tests. Disposals is reversible and may go away.
Get HPV vaccine. ...Read more

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Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia. What should my concern be?

Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia. What should my concern be?

Pap smear: Is this the result of your pap smear? if yes, then it means moderate or severe cervical intraepithelial neoplasia or carcinoma in situ, which in some cases could lead to cervical cancer. you need Colposcopy and possible biopsy.
Talk to your Gynecologist regarding a treatment plan. ...Read more

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If you have high-grade cervical dysplasia, do you have cancer cells?

If you have high-grade cervical dysplasia, do you have cancer cells?

Not likely: High grade dysplasia is pre-cancerous, but patients with high grade dysplasia are susceptible to developing cancer. Because of the very high risk of developing cancer in association with high grade dysplasia, most patients are treated by a procedure called leep/cone. However, the treatment process is a collaboration between the patient and gyn, and you could request a second pathology review. ...Read more

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If you have high-grade cervical dysplasia, does that mean that you have cancer cells?

If you have high-grade cervical dysplasia, does that mean that you have cancer cells?

No: A high-grade squamous intraepithelial lesion (hsil) on pap smear typically equates to moderate to severe squamous dysplasia on cervical biopsy, a precursor to invasive cancer with high-grade lesions being more likely to progress (as opposed to low-grade lesions). Areas of high-grade dysplasia are typically surgically excised so that the chance of progression to invasive cancer is minimized. ...Read more

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Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?

Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?

Pap: You need to have your pap test repeated in 3 months to see if has reverted to normal, by in itself cells with dysplasia only means that you may have had a past infection or may have HPV ...Read more

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How long does it take for severe dysplasia to progress to cervical cancer if not all abnormal cells are found and removed?

How long does it take for severe dysplasia to progress to cervical cancer if not all abnormal cells are found and removed?

Varies: It could be 5-10 years or it could resolve on its own depending on cause of the dysplasia and risk factors. Work on eliminating risks like smoking, synthetic hormones (oc's), multiple partners. Work on improving immune system with weight loss, organic chemical free diet, exercise, and immune boosting supplements. ...Read more

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Have had dysplasia in the past, had cells removed. Waiting for reg pap smear before trying to get pregnant again. Would dysplasia affect pregnancy?

Have had dysplasia in the past, had cells removed. Waiting for reg pap smear before trying to get pregnant again. Would dysplasia affect pregnancy?

Not at all: If you feel comfortable waiting until a normal pap result is returned before getting pregnant that is fine, but dysplasia should not affect any pregnancy. Women who are found to have dysplasia while pregnant are usually just followed closely and any treatment is delayed until after the six week postpartum visit. ...Read more

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My 65 year mothers pap smear report says squamous epithellial cells of mainly intermediate and parabasal type. Moderate anisonucleosis and dysplasia?

The key is dysplasia: She will need a colposcopy and biopsy of the cervix and ecc and may need a leep or cervical cone or possible hysterectomy depending on how bad the dysplasia is or if she has worse (hopefully not) cancer in situ. ...Read more

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Dysplasia cells in the lining of my stomach. What is the likely hood of turning to cancer. I see my dr in 6 months.

Dysplasia cells in the lining of my stomach. What is the likely hood of turning to cancer. I see my dr in 6 months.

It really depends: The chances of turning into cancer depends on many factors, the main one being if it is high or low grade. Other factors that may need to be addressed would be a possible infection such as h pylori playing a role or excessive acid production. I would recommend you clarify precisely what the finding was and what the treatment and follow up should be with the diagnosing physician before 6 months. ...Read more

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LEEP in Apr. '14, clean margins. Jul. '14 - high grade dysplasia recurs, plus atypical glandular cells. Doc advises hysterectomy. Is this overkill?

LEEP in Apr. '14, clean margins. Jul. '14 - high grade dysplasia recurs, plus atypical glandular cells. Doc advises hysterectomy. Is this overkill?

NO: If truly recurrent dysplasia and no fertility desired, then this is completely a very good option and will give the best result as far as future prognosis. Consider whether removal of the ovaries too may be in your best interest at 46 yo. Discuss with your GYN. Consider a laparoscopic surgery as this allows return to normal faster - but only by really qualified surgeons - not every GYN knows well. ...Read more

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I have had 2 abnormal paps. A follow up with a specialist revealed HSIL and moderate dysplasia. My understanding is that this is a pre cancerous condition and that I may have to have a hysterectomy. What is the best course of action and what does this d

I have had 2 abnormal paps. A follow up with a specialist revealed HSIL and moderate dysplasia. My understanding is that this is a pre cancerous condition and that I may have to have a hysterectomy. What is the best course of action and what does this d

Abnormal pap smears: The diagnosis of moderate dysplasia does not have to eventuate in a hysterectomy as it is not a cancerous condition yet. You DO need to follow up with the MD at least every 6 months to be sure that the dysplasia does not progress to actual cervical cancer. There are Rx options prior to hysterectomy if the dysplasia is caught before invasive cancer. Ask your MD about his/her follow up plans. ...Read more

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I asked about thanataphoric dysplasia & I understand it is a new gene mutation, in which cell? Sperm or ova? Or permeant change in ovary?

I asked about thanataphoric dysplasia & I understand it is a new gene mutation, in which cell? Sperm or ova? Or permeant change in ovary?

Neither: The new gene mutation in thanatophoric dysplasia is not related to parental ova or sperm, but can represent missense mutations in fibroblast growth factor receptor-3. ...Read more

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Hph positive. Last pap EPITHELIAL CELL ABNORMALITY LGSIL, Mild DYSPLASIA. I am also immunocompromissed. Treatment? Opinions? Want to compare with my Gyn

Hph positive. Last pap EPITHELIAL CELL ABNORMALITY LGSIL, Mild DYSPLASIA. I am also immunocompromissed. Treatment? Opinions? Want to compare with my Gyn

Watch it closely: Nobody here can advise you without a full knowledge of your pap smear history, your smoking habits, HPV status if known, personal wishes, and why you're immunocompromised. Simply ask you physician, "Is the guidance you're giving me in keeping with the Bethesda protocols / other consensus documents? " It'll be close follow-up versus biopsy. Best wishes. ...Read more

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What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma (transitional)?

What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma (transitional)?

Location: What is the source of the biopsy? In the paranasal sinuses inverted papilloma is a sinus tumor traditionally treated with surgery, especially if there are foci of carcinoma. ...Read more

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What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra). With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more

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My PAP came back with "epithelial cell abnormality. LGSIL; mild dysplasia and human papilloma virus effects are present". What does this mean?

HPV, dysplasia: You have HPV and it has caused minor cellular abnormalities in your cervix. L (G)SIL stands for low (grade) squamous intra-epithelial lesion, usually due to a low risk (non cancer-causing) type of HPV. Most likely this is not serious, but follow your doctor's advice on follow-up testing and perhaps treatment. Get vaccinated to prevent more serious HPV infections and get tested for other STDs. ...Read more

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Esophageal mucosal fragments reveal moderate mixed inflammatory cell infiltrate compromising neutrophils, lymphocytes, foci of mild dysplasia. Bad?

Maybe: Please check your report and see if there is any mention of barrett's esophagus or intestinal metaplasia. These findings would indicate a premalignant component that requires regular, lifetime followup. The finding of mild dysplasia may require additional medicines for a while, but please followup with your gastroenterologist that did the biopsy. ...Read more

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Describe the features of bronchopulmonary dysplasia (b.P.D.).?

Describe the features of bronchopulmonary dysplasia (b.P.D.).?

Oxygen dependency: Bpd is a disease of the lungs of premature babies. Specific definitions vary, however is is generally defined as oxygen need at about one month of age. It typically results from long term mechanical ventilation in premies. The lungs continue to grow for he first few years of life and many outgrow the condition. ...Read more

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What is dysplasia?

Bad + formation: The term is derived from the greek roots dys= bad & plassein =to form. It has been applied to situations where body parts didn't develop properly during pregnancy or after birth. Bony dysplasia= bones formed wrong. It is also applied to situations where the bad formation occurs later= tumors where a normal tissue converts to a new "bad"pattern of growth. ...Read more

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What is skeletal dysplasia?

Abnormal bones: Skeletal dysplasias represent abnormal structure and development of bones. Some are genetic in their development. Dysplasia is classified according to part of bone affected, epiphysis, metaphysis, or diaphysis Bone deformities can develop and often dwarfism is result of bone dysplasia. ...Read more

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What is dysplasia vs neoplasia?

What is dysplasia vs neoplasia?

Precancerous Cells: Dysplasia is considered pre-cancerous and is usually graded by severity (mild-moderate-severe). On the cervix, mild dysplasia = mild cervical intra epithelial neoplasia or cin i. The words are often interchangeable and both mean "precancerous". I hope that helped, take care. ...Read more

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Can you tell me about skeletal dysplasia?

Can you tell me about skeletal dysplasia?

Abnormal bones: Skeletal dysplasias represent abnormal structure and development of bones. Some are genetic in their etiology. Dysplasia is classified according to part of bone affected, epiphysis, metaphysis, or diaphysis Bone deformities can develop and often dwarfism is result of bone dysplasia. ...Read more

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Focal high grade dysplasia is very dangerous?

Needs evaluation: You have precancerous cells on the cervix most likely due to the human papilloma virus.
Your next step should be colposcopy and biopsy and later most likely a LEEP procedure where the surface of the cervix is removed as an office procedure. ...Read more

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How often should I be tested if I have dysplasia?

Your doctor is your: Your best guide is your doctor who gave you this diagnosis. Most such reports require follow up anywhere between 6 monthly to once yearly. Where is this dysplasia located?
Please check with your doctor about further follow up. ...Read more

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What is the definition or description of: dysplasia?

Abnormal cells: Abnormal cells which may be pre-malignant, but can also result from infections and inflammation. ...Read more

Dr. Linda Callaghan
1 Doctor shared a insight

Dysplasia (Definition)

Abnormal cells which may be pre-malignant, but can also result ...Read more