Doctor insights on:
Precancerous Cells Vs Dysplasia
I had a thyroid biopsy of a single nodule which shows dysplasia. Could it still be cancer if it shows precancerous cells on biopsy?
It could be: Thyroid nodules are quite common. Many of them are benign but cancer is not uncommon in the thyroid gland. The needle biopsy can misread them. So the safest course is to have excision removal anytime there is suspicion like in your case: dysplasia, usually implies abnormal cells which can be cancerous. ...Read more
A precancerous condition (or premalignant condition) is a generalized state associated with a significantly increased risk of cancer. If left untreated, these conditions may lead to cancer. Premalignant lesion is a morphologically altered tissue in which cancer is more likely to occur than ...Read more
Had severe dysplasia (had leep) , now breakthough bleeding. Any connection with precancerous cells of the uterus and cervical dysplasia?
It is unlikely that: Your irregular bleeding is related to the leep or utrine cancer unless the leep was recently done and u r bleeding from there. Cervical cancer and uterine cancer are seperate phenomenon, though cervical cancer can extend into the uterus. Depending on age, uterine cancer is low on the list as a cause of the bleeding but see your doc if older than 35, may need endometrial biopsy just 2 b sure? ...Read moreSee 2 more doctor answers
I was just told I had an abnormal pap test. What does it mean to have mildly abnormal dysplasia cells?
A premalignant state: Carcinoma of the cervix, a common malignancies of uterus begins in the premalignant state. The Pap test reveals cells that already show signs of transformation or dysplasia. Detecting transforming cells by cytology, , is about 60%. This improves by sampling for HPV to about 80%. We have developed a new mAb (squamous) that gives better than 90% accuracy by IHC ...Read moreSee 1 more doctor answer
What does it mean to have abnormal cells on your pap smear? I was told i had dysplasia cells? should i worry?
Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia. What should my concern be?
Pap smear: Is this the result of your pap smear? if yes, then it means moderate or severe cervical intraepithelial neoplasia or carcinoma in situ, which in some cases could lead to cervical cancer. you need Colposcopy and possible biopsy. Talk to your Gynecologist regarding a treatment plan. ...Read moreSee 1 more doctor answer
Not likely: High grade dysplasia is pre-cancerous, but patients with high grade dysplasia are susceptible to developing cancer. Because of the very high risk of developing cancer in association with high grade dysplasia, most patients are treated by a procedure called leep/cone. However, the treatment process is a collaboration between the patient and gyn, and you could request a second pathology review. ...Read more
No: A high-grade squamous intraepithelial lesion (hsil) on pap smear typically equates to moderate to severe squamous dysplasia on cervical biopsy, a precursor to invasive cancer with high-grade lesions being more likely to progress (as opposed to low-grade lesions). Areas of high-grade dysplasia are typically surgically excised so that the chance of progression to invasive cancer is minimized. ...Read moreSee 1 more doctor answer
Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?
How long does it take for severe dysplasia to progress to cervical cancer if not all abnormal cells are found and removed?
varies: It could be 5-10 years or it could resolve on its own depending on cause of the dysplasia and risk factors. Work on eliminating risks like smoking, synthetic hormones (oc's), multiple partners. Work on improving immune system with weight loss, organic chemical free diet, exercise, and immune boosting supplements. ...Read more
Have had dysplasia in the past, had cells removed. Waiting for reg pap smear before trying to get pregnant again. Would dysplasia affect pregnancy?
Not at all: If you feel comfortable waiting until a normal pap result is returned before getting pregnant that is fine, but dysplasia should not affect any pregnancy. Women who are found to have dysplasia while pregnant are usually just followed closely and any treatment is delayed until after the six week postpartum visit. ...Read moreSee 1 more doctor answer
Dysplasia cells in the lining of my stomach. What is the likely hood of turning to cancer. I see my dr in 6 months.
It really depends: The chances of turning into cancer depends on many factors, the main one being if it is high or low grade. Other factors that may need to be addressed would be a possible infection such as h pylori playing a role or excessive acid production. I would recommend you clarify precisely what the finding was and what the treatment and follow up should be with the diagnosing physician before 6 months. ...Read more
LEEP in Apr. '14, clean margins. Jul. '14 - high grade dysplasia recurs, plus atypical glandular cells. Doc advises hysterectomy. Is this overkill?
NO: If truly recurrent dysplasia and no fertility desired, then this is completely a very good option and will give the best result as far as future prognosis. Consider whether removal of the ovaries too may be in your best interest at 46 yo. Discuss with your GYN. Consider a laparoscopic surgery as this allows return to normal faster - but only by really qualified surgeons - not every GYN knows well. ...Read more
I have had 2 abnormal paps. A follow up with a specialist revealed HSIL and moderate dysplasia. My understanding is that this is a pre cancerous condition and that I may have to have a hysterectomy. What is the best course of action and what does this d
Abnormal pap smears: The diagnosis of moderate dysplasia does not have to eventuate in a hysterectomy as it is not a cancerous condition yet. You DO need to follow up with the MD at least every 6 months to be sure that the dysplasia does not progress to actual cervical cancer. There are Rx options prior to hysterectomy if the dysplasia is caught before invasive cancer. Ask your MD about his/her follow up plans. ...Read more
I asked about thanataphoric dysplasia & I understand it is a new gene mutation,in which cell? Sperm or ova ? Or permeant change in ovary?
Are there malignant cells in the semen of a man with multiple myeloma? If so can this be dangerous for a woman with a history of cervical dysplasia?
Hph positive.last pap EPITHELIAL CELL ABNORMALITY LGSIL, Mild DYSPLASIA.I am also immunocompromissed.Treatment? Opinions? Want to compare with my Gyn
Watch it closely: Nobody here can advise you without a full knowledge of your pap smear history, your smoking habits, HPV status if known, personal wishes, and why you're immunocompromised. Simply ask you physician, "Is the guidance you're giving me in keeping with the Bethesda protocols / other consensus documents?" It'll be close follow-up versus biopsy. Best wishes. ...Read more
What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?
What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?
Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more
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