Doctor insights on:
Prazosin Hydrochloride Sympathetic Nervous System Inhibitor
Essentially yes: Originally marketed as an antiepileptic medication the description of "calming" the nervous system is essentially accurate in how it functions. If you have further questions on the function of this medication and you'd like a 1-1 consult don't hesitate to contact me at: www.healthtap.com/drsaghafi Key Code: PDXFNR to set up a calendar appointment. ...Read moreSee 1 more doctor answer
Do any beta blockers act on Central Nervous System? Labetalol, Propranalol? What about Alpha-1 blockers?
Yes, most of them: Beta blockers are either water soluble or lipid soluble. The latter cross the blood-brain barrier and act on the CNS (central nervous system). Atenelol and Naldolol are 2 water soluble ones that do not readily cross into the brain. Alpha blockers generally do act on the CNS, and the 2 most common side effects are hypotension and dizziness. ...Read more
Sertraline mechanism: Zoloft (sertraline) does not calm the entire nervous system, it specifically works a part that uses serotonin. It is a serotonin re-uptake inhibitor. This is meant to change levels of a neurotransmitter involved in the feelings of depression and anxiety. It does not affect many other neurotransmitters in the nervous system, such as dopamine, glutamate, etc. ...Read more
Do selective adeno-adenergic blockers (prazosin, terazosin, doxazosin, trimazosin) protect from acute cocaine-induced vasoconstrictive damage?
Some: Cocaine causes it's effect by preventing the reuptake of monamine (epinephrine, etc) and causes these neurotransmitters to continue exciting the a1 receptor. The meds listed block alpha-1 receptors, so theoretically will blunt the effects of Cocaine on some vessels, but focus mostly (esp. Tamsulosin) on a specific sub-type (alpha-1a) that is mostly in the bladder, not in the vessels. ...Read moreSee 1 more doctor answer
Can being on high doses of ritalin (methylphenidate) (prescribed) for 15 years cause dysautonomia? Sympathetic nervous system disorder?
Can you tell me examples for central nervous system, peripheral nervous system, somatic nervous system?
OK: Central nervous system - brain & spinal cord Peripheral nervous system - all the nerves that come out from the brain and spinal cord. Within the peripheral nervous system you have 'somatic' and 'visceral' nervous systems. Somatic refers to muscle, skeleton, skin. Visceral refers to internal organs. In a nutshell! ...Read more
Why do the cholinergic agonist drugs act on the parasympathetic (but not the sympathetic) nervous system?
Only noradrenergic antidepressant works for me, does inderal (propranolol) acts negative on noradrenergic effects of antidepressant ?At vasomotor centers.Regards.
Venlafaxine: It's not the vasomotor centers that are important in antidepressant response; it's the neuron synapses in the brain. Effexor (venlafaxine) inhibits reuptake of both serotonin and ne. Inderal can suppress some of the physical symptoms of anxiety (rapid heart rate, sweaty palms, tremulousness, etc). Some on chronic (not intermittent or "prn") Inderal have had more depression. Not everyone. You should be okay. ...Read more
Can overuse of a centrally acting stimulant like Pseudoephedrine trigger apermanent change in adrenergic receptors...hypersensitive sympathetic systm?
Not likely: Adrenergic drugs are used to manage sympathetically maintained pain. They act either presynaptically on the neuron or postsynaptically on receptors located on the effector organ. They may affect receptors that are stimulated by norepinephrine (NE) or epinephrine, or interrupt the release of NE from noradrenergic neurons. ...Read more
Zoloft (sertraline): Yes it is. Dopamin reuptake inhibition increases as dose increase. ...Read more
Most newer ones: Most of the newer antidepressant medications affect specific neurotransmitters. Each does it slightly differently, accounting for the different response rates amongst them. The SSRI's primarily increase serotonin, the SNRI's both serotonin and norepinephrine, and buproprion mostly norepinephrine alone, and Brintellix affects many of them in different ways and in different places in the brain. ...Read more
Which drugs? Attack?: Many drugs act on the brain, some because they are meant to, others as side effects. Very few drugs damage the cns. The ones that are known to cause permanent changes are alcohol and stimulants like cocaine/crack and methamphetamine when used for long periods. Tolerance to opioids and benzodiazepines takes a year or so to disappear completely, but the effects are thengone. ...Read moreSee 1 more doctor answer
U need 2 do the work: You shouldn't post such questions on HealthTap. Answering them is not a good use of HealthTap doctors' time. There are many websites with free interaction checkers you can use yourself e.g. Drugs.com, Epocrates, Medscape, Webmd & numerous others. What's more, doing it yourself will make you a better patient & put you in better control of your care because you'll learn, understand & remember more. ...Read more
Dysautonomia: Several, such as Adrenal fatigue, Headaches, Hypertension, Heart disease, Food sensitivities, Chronic fatigue, Fibromyalgia, Depression, Anxiety, Alcoholism, Compulsive overeating, Insomnia, Irritable bowel, Obesity, ADHD, Overactive bladder, PTSD, Alzheimer, Parkinson's disease, Excess sweating. ...Read more
Can an antagonist (propranolol) cause an inhibitory effect via beta-adrenoreceptors in cardiac myocytes?
Beta blockers: Yes.Get a more detailed answer ›
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