Doctor insights on:
I have taken 5x1mg pramipexole for years to control RLS, and it has been effective. Now another Dr. Says this a very high dosage. Who is correct? .
VARIABLE: If you are currently taking Mirapex for rls, and it is not working well, success will not be achieved by continuing to push the dose upwards, as this is more likely to increase side effects, such as nausea, postural hypotension, drowsiness, and even impulse disorder. Talk with your doctor about using the newer Neupro (rotigotine) patch, which could be effective for 24 hrs and perhaps fewer side effects. ...Read more
Yes: This is a rare but possible side effect. ...Read more
Allergic?: "allergy" means a hypersensitivity reaction of the immune system. This is always itching with or without rash/hives, angioedema (swelling e.g. Of throat), or systemic anaphylaxis which is life-threatening. Everything else is just an adverse reaction or intolerance of which there are very many. Many web sources can give you lists of side effects of mirapex (pramipexole). ...Read more
Dopamine.: Drrugs which stimulate dopamanergic receptors can be associateed with sexual"urges." your term, not mine. But if it were truly an aphrodisiac, everyone would be on it! Buproprion an antidepressant, also a Dopamine stimulator claims this as a side-effect. ...Read more
Wanted to replace mirapex (pramipexole) with horizont for RLS my ins. Won't cover it, any other suggestions?
Yes: Neurontin (gabapentin) helps me. Also if u failed other drugs u can appeal 2 ur insurance company. Also klonapin helps. Failed multiple other drugs and on appeal medicare covered the Klonopin even though they do not cover any benzodiazapans or their derivatives. ...Read moreSee 1 more doctor answer
What would cause new break through flare ups of RLS I've been taking 1mg of mirapex (pramipexole) now it doesn't work I have problems at 3pm never needed meds til 7?
Yes, with caution: Pramipexole has shown benefit in research trials in treating depression symptoms in bipolar disorder. However, it can also "flip" depressed patients to mania. Patients who try it should be on a good anti-manic regime before adding pramipexole. ...Read moreSee 2 more doctor answers
Supportive: Mirapex (pramipexole) is a Dopamine agonist. Dopamine in excess in your body will cause nausea, vominting and increase in blood pressure and heart rate. Standard therapy would be usuall decontamination if early overdose (within and hour) inducing vomitng. If having symptoms go to er or notify your doctor. Treatment is IV fluids and monitoring until drug gets out of systme. ...Read more
Mirapex (pramipexole) online: Sure, if u want to compromise quality & cost, since purity of online products not guaranteed & cost high. ...Read more
Refills: Refills are not any issue. However - with opioids most MD's in the US will and should not just issue refills without you being seen. ...Read more
Motor symptoms: Mirapex (pramipexole) is good for the motor symptoms of parkinson disease. It should help the tremors, rigidity, and to some degree the bradykinesia. Mirapex (pramipexole) also has good data for depression, which is very common in parkinson disease. It will not help symptoms such as dementia, and may aggravate things like hallucinations and hypotension. ...Read more
Early Parkinson's: Would use this for mild and early disease, usually, and it may help tremor, stiffness, and even gait, but likely will benefit for maximum of 2 years. Early usage may prevent later dyskinesias or at least delay need for l-dopa when disease is worse, can use for add on benefit, and may stabilize for a time. ...Read more
What to do if I cannot swallow pills and I was wondering if it'd be okay to chew a pramipexole 0.25 mg tablet?
I have chronic RLS after 3yrs on mirapex (pramipexole) it now causes symptoms to worsen! Also on codeine sulfate. What's next? Thought i'd found the relief
Troublesome!: Rls is very troublesome. All the meds we use show tolerance over time. You can google the laundry list of meds we use (sinemet, klonopin, neurontin, mirapex, (pramipexole) etc.) but your best bet is to sit down with a sleep specialist in your area. He/she can guide next med selection. Btw, occasionally 400 mg of magnesium helps before bedtime. Cheap, too. Best of luck! ...Read more
My doctor said 1mg of mirapex (pramipexole) is as hi as I can go for RLS what happens if we go higher
Consider: If for whatever reason, the amount of Pramipexole you are taking, is not doing the job, perhaps a Neupro (rotigotine) patch might work better, or another class of drug may be the choice. Spend a good deal of time fully considering options with your doctor. ...Read moreSee 1 more doctor answer