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Was on many medications for confirmed MS (rebif, copaxone, gilenya, tysabri, (natalizumab) tecfidera) none helped control.. Is this typical of ms? Next step?
Unusual but possible: Visit an ms center.Get a more detailed answer ›
Are there studies that demonstrate that lyrica (pregabalin) controls seizures better than neurontin? References?
Very effective: MRI is indeed "Gold standard", and helps us make decisions regarding diagnosis and changes in therapy. Note you state diagnosis of MS, but do NOT find any disease modifying drug listed. Prednisone is fine for relapse, and IVIG might be used if you were pregnant, but neither helps control the disease chronically. Note fresh frozen plasma, and this too, has no role in MS therapy. ...Read moreSee 1 more doctor answer
Please repost: Not sure what you're asking. A symptom is what a patient experiences & tells the clinician. A sign is what the clinician finds on examination. You like the symptoms & signs to match up. That makes everything easier. You can have symptoms without signs ("I feel jittery") & vice versa, e.g. a heart murmur or elevated blood pressure. You need to rephrase your question so it makes sense. ...Read more
So complicated: In short, no - migraines are not a hypoperfusive state. The old (not correct) understanding in fact was based on the observation that blood flow often increases with migraines. Like all things in the body, our understanding now is much more complicated. There's a complex interaction between the neurons (primary problem) and the vessels and surrounding structures (secondary). ...Read more
Nortriptyline: Nortriptyline which is a tricyclic antidepressant has been shown to be helpful for depression in those with parkinson's disease. Also paroxetine has some evidence for treating depression in parkinson's. In general antidepressants that work on norepinephrine and Dopamine seem to help more. Antidepressants that affect serotonin can worsen movement symptoms common in pd such as restless legs. ...Read moreSee 2 more doctor answers
Tremors in hands, weak legs, mem issues, cognitive decline, apathy, blurry vision, tach, headache, floaters...Could it be parkinsons? Dementia? Als?
How to diagnose MS: There are MS symptoms, and then there are symptoms that help to make the diagnosis of MS. For example, muscle spasm is a symptom of MS, and many other illnesses. Lesions of the brain are caused by MS, but also by viruses, head injuries, etc. If you have the right symptoms and the right MRI findings, the diagnosis should be clear. With MS, the diagnosis is rarely that easy to make. ...Read moreSee 2 more doctor answers
What about it?: Perhaps you can state your question more clearly. Healthtap is not a search engine. It's a place for asking questions and receiving answers from doctors. Unfortunately none of us is a mind reader and we cannot guess what a person's intent is when they put a couple of words together and a question mark at the end. A question mark at the end of a phrase doesn't turn the phrase into a question. ...Read moreSee 1 more doctor answer
Fleisher et al (Neurology, 2011) found Depakote accelerated brain atrophy in Alzheimer's. Should those with family history of Alz. avoid Depakote?
Usualiy not.: Usualiy not, but nobody can predict.Get a more detailed answer ›
Severe paresthesia in extremities. Negative for MS (brain and spinal MRIs), negative EMG & NCS. On Lyrica (pregabalin) & Cymbalta but no relief. Recommendations?
More info req'd: It sounds like you've had a complex Neurological work-up and are intereted in seeking a second opinion. I would be glad to help, yet would need to see more data before throwing a diagnostic assumption at you. Please gather your medical records (labs/imaging/etc) and schedule a virtual consult with me for further details. I'm interested and available. ...Read moreSee 1 more doctor answer
L'hermittes occurred w/o other MS symptoms. Mri of c spine & brain clear. Vep ok. But- lumbar puncture detected bands. What are chances of having ms?
Fairly high, but: There are other causes for lhermitte's such as vitamin b-12 problems, and even lyme disease. Make certain that other potential disorders are excluded. Although the oligoclonal bands correlate very highly with ms, other immune disorders could cause presence. Maybe check peripheral nerve function on a screening emg, just to be sure. Most docs would do followup MRI in 6 months. ...Read more
Neuropathy: Treatment for multifocal motor neuropathy varies. Some individuals experience only mild, modest symptoms and require no treatment. For others, treatment generally consists of intravenous immunoglobulin (ivig) or immunosuppressive therapy with cyclophosphamide. ...Read moreSee 1 more doctor answer
May be: Only time will tell about the improvement it all depends what is the extent of permanent damage. ...Read more
Have symptoms of MS (blurry vision, pain, fatigue, muscle weakness) but have normal evoked potentials. Brain MRI w/ white matter changes? Still be ms?
Recommend:: Your symptoms are nonspecific and could be due to many conditions. Mri lesions could be due to migraine or prior head injuries, and your doctor could describe whether the pattern is consistent with a specific cause. I no longer use evoked potentials to confirm ms, and rarely use for any reason. If things seem unclear, a lumbar puncture may be useful. Discuss all of this with neurologist. ...Read more