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Doctor insights on: Post Essential Thrombocythemia Myelofibrosis

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How many people have essential thrombocythemia (ET)?

Quite common: For the whole population, maybe 1 person in 2000. It's more common in older folks, less so in youngsters. ...Read more

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Is there a connection betwen essential thrombocythemia and leukemia?

Is there a connection betwen essential thrombocythemia and leukemia?

Yes-5% risk: Essential thrombocythemia is part of myeloprolifeartive neoplasm umbrealla where in et the bone marrow for some uknown reason-proliferate too much platelet- that can go up above a million. They are abnormal and sticky platelet. Due to the abnormal level and function of platelet, there would be risk for blood clots as well as bleeding. The risk of et to develop into acute leukemia is about 5 %. ...Read more

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I have essential thrombocythemia and I am taking anagralide. Is this right?

I have essential thrombocythemia and I am taking anagralide. Is this right?

Drugs: Yes, Hydroxyurea and Anagrelide are widely used to treat essential thrombocythemia. There are pros and cons with those two medications. Follow up and discuss in detail with your doctor. ...Read more

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Is essential thrombocythemia a form of cancer?

Is essential thrombocythemia a form of cancer?

Neoplasm: Essential thrombocythemia (et) is part of group of myeloproliferative neoplasm (mpn) - is a clonal disorder. Mpns are predisposed to clonal evolution and disease transformation to myelodysplasia and/or acute leukemia. The propensity to transform into acute myeloid leukemia differs among the subgroups- being the highest for cml- greater than 90% if left untreated and et being the least - about 5%. ...Read more

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Treatment of essential thrombocythemia with phildephia +ve?

Treatment of essential thrombocythemia with phildephia +ve?

Platelets: Need more information like what is your platelts count and any symptoms. No symptom-no treatment. Since you have diagnosis of essential thrombocythemia and tested positive for philadelphia chromosome mean you have hematologist who has ruled out other causes of thrombocythemia and any lymphocytic leukemia connection. Please stay in touch with hematologist. Wish you best of health. ...Read more

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Is there any alternate treatment for essential thrombocythemia?

Is there any alternate treatment for essential thrombocythemia?

ET: Hydroxyurea, anagrelide, and alpha-interferon are conventional therapies for essential thrombocythemia. Pipobroman is widely used in europe, but not available in the United States. Low-dose Aspirin is possibly effective in preventing thrombosis (clot formation) in et. Low-dose asa is especially effective in managing the vasomotor symptoms of et. ...Read more

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What is the essential thrombocythemia?

What is the essential thrombocythemia?

ET: It is a condition under myeloproliferative neoplasme umbrella where- for unclear reason- bone marrow produce too much platelet that can go beyond a million. They are sticky and abnormal platelets that can cause blood clots or bleeding. Myeloproliferative neoplasm can transform into acute leukemia. The risk of et to develop acute leukemia is about 5%. Discuss further with your hematologist. ...Read more

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What exactly is essential thrombocythemia?

What exactly is essential thrombocythemia?

ET: Et is one of the myeloproliferative neoplasms. It causes overproduction of platelets and a susceptibility to clotting and, occasionally, bleeding problems. Whether one needs treatment depends on the patient's age, previous disease-related complications, and underlying cardiovascular status. Several good support groups can be found on the internet. ...Read more

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I have essential thrombocythemia. Is this a life long disease?

Yes: Treatment of essential thrombocythemia depends on your risk of blood-clotting or bleeding episodes. If you're younger than 60, have had no signs or symptoms, and have no other risk factors for developing blood clots, such as smoking, you may simply need periodic medical checkups. ...Read more

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What are the treatment for essential thrombocythemia?

What are the treatment for essential thrombocythemia?

ET treatment: A drug called hydroxy-urea will be the treatment to reduce platelet levels. Then on the high risk group, Aspirin will be needed too. Discuss in detail with your hematologist. ...Read more

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What does myeloproliferative disorder with essential thrombocythemia mean?

What does myeloproliferative disorder with essential thrombocythemia mean?

Too many platelets: The myeloproliferative neoplasms (mpns) involve terminal myeloid cell expansion in the peripheral blood, resulting in various combinations of erythrocytosis (rbc's), leukocytosis (wbc's), thrombocytosis (platelets), bone marrow hypercellularity/fibrosis, and splenomegaly (enlarged spleen). Essential thrombocythemia is a diagnosis of exclusion, made when other forms of mpn are ruled out. ...Read more

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What is a myeloproliferative disorder that includes essential thrombocythemia?

What is a myeloproliferative disorder that includes essential thrombocythemia?

Too many platelets: Myeloproliferative disorders are a set of marrow malignancies characterized by excessive production of certain types of blood cells. Essential thrombocytopenia is one of them, in which marrow makes too many platelets. There are well-tolerated oral agents which help. Other myelodysplastic syndromes are polycythemia vera and chronic myelogenous leukemia. ...Read more

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What is the difference between polycythemia vera and Essential thrombocythemia?

What is the difference between polycythemia vera and Essential thrombocythemia?

See below: Polycythemia vera (PV) is characterized by uncontrolled production of red blood cells along with specific JAK2 gene mutation and decreased EPO level. Essential thrombocythemia (ET) comes with uncontrolled elevation in platelet count. JAK2 mutation occurs only in 50% of ET. Bone marrow biopsy may be required for the diagnosis of ET. Both are clonal myeloproliferative neoplasms. ...Read more

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Is essential thrombocythemia a form of blood cancer? Please advise!

Is essential thrombocythemia a form of blood cancer? Please advise!

By definition: All overgrowths of blood cells and the elements that form them are by definition cancer, since blood cells by their nature travel through the body. Given this, "ET" isn't even a life-shortener on the average, and I hope your illness proves manageable if it needs to be managed at all. ...Read more

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Please let me know if there is any alternate treatment for essential thrombocythemia or high platelets?

Please let me know if there is any alternate treatment for essential thrombocythemia or high platelets?

Always alternatives: There are alternative treatments for everything. However, the question is whether any are effective for ET. None are yet proven but a healthy diet, detoxification, exercise, herbs like turmeric, Japanese Knotweed & medical marijuana, stress reduction, homeopathy and acupuncture are worth exploring.
See http://medicalmarijuana. Com/medical-marijuana-treatments/E-T-
Work with an integrative doctor. ...Read more

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Is it true that essential thrombocythemia is a form of blood cancer?

By definition: Since the cells of the blood invade tissue, all tumors / clonal overgrowths are by definition cancers. Essential thrombocythemia can usually be kept at bay easily for decades. ...Read more