Doctor insights on:
Positive Antinuclear Antibody Test
Any one: Depending on the concentration/titer of the antibody, it may be a false positive if it is low titer; if the titer is high it may portend an auto-immune disease like lupus or arthritis. However the person with ANA is still susceptible to all other diseases that affect other people with similar genetic background and environment. ...Read more
ANA - not diagnostic: The ANA (anti-nuclear antibody) can be present for many reason. It is classically seen in sle, but most people was a + ANA do not have lupus or a connective tissue disease. You evaluation will help clarify why you have the + ANA and how it relates to your medical condition. ...Read more
My ANA (antinuclear antibody) test came back positive, how worried should I be? Do normal people have this?
Many False +: ANA is a screening test for autoimmune disease. False + are common. False negatives are rare. Yes, normal ppl do have this appear + sometimes. The lab should also indicate how positive the test was: mildly or strongly. Follow up tests to the ANA (such as dsdna and complement among many others) can determine if this was a true positive or false positive. ...Read moreSee 1 more doctor answer
Autoimmune disease: ANA (anti-nuclear antibody) is a blood test used by doctors that indicates the presence of an autoimmune condition in which the body's immune system is predisposed to recognize normal things in your body as foreign invaders that need to be attacked. The results are not specific for any particular disease if positive, but are a preliminary test, after which a range of possibilities are considered. ...Read more
What is a "positive antinuclear antibody with a homogeneous staining pattern & a litre of 1 in 160" ... & should I worry ?
Yes: Yes, the ANA is sensitive in the case of lupus erythematosus meaning that if you have lupus, the ANA will be positive over 99% of the time (few false negatives). However, it is very non-specific meaning that if you have a positive ana, you may have lupus or some other disease or nothing at all (many false positives). ...Read more
What does a borderline antinuclear antibody test homogeneous pattern 1:80 and sedrate westergreen 51 mean?
Not Much.: Doesn't really mean much without a compatible clinical syndrome. First you need symptoms then you need a test to tell you if the symptoms are real. Getting a test first then looking for symptoms is bad practice, often confusing and frustrating. Your current lab results may be perfectly normal for you. ...Read more
Connective Tissue Dx: With a positive ana, you must now characterize it. The positive anticardiolipin abs need to quatified for the 3 types: igg, igm, and iga. The ones that are likely to cause thrombotic issues are in order: igm, igg, and iga. You need a rheumatologic or immunologic evaluation. ...Read more
How often should I see a rheumatologist again, if my antinuclear antibody is positive, but i'm not sick?
It depends: If the rheumatologist has told you nothing else is showing up, you may not need to see the specialist again for a long time, or ever. Lots of people have a positive ANA and it doesn't always mean there is a disease state. If it's very high, you are at higher risk of getting something, but if low, your primary care can recheck it annually as long as you continue to feel well. Ask the rheum. ...Read more
Is an antinuclear antibody blood test result of 1.32 low, medium, or high? Is it something to worry about?
If 1:320, high-ish: Anas are reported as a ratio of how dilute the serum is when the antibody is still detectable, and the lowest ratio reported is usually 1 to 40, written 1:40. Meaning if you dilute the serum 40 fold, you can still find antibody. The next reading is 1:80, then 1:160, then 1:320. The number you write looks like it could be 1:320. That's a significant amount and might cause symptoms. Make appt w doc. ...Read more
Will antinuclear antibody test detect dormant syphilis? I am waiting on results and had a RPR test came back was non reactive.
Very unlikely: I am unaware of any association between the two. ...Read more
Not necessarily: In addition to sle a positive ana(antinuclear antibody) can be seen in a number of medical conditions, secondary to certain medications, and in otherwise healthy individuals. Therefore a positive ANA does not necessarily indicate the presence of sle. ...Read moreSee 1 more doctor answer
My results showed that I have antinuclear antibody on cardiolipin ab (igg). What are the implications?
Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read moreSee 1 more doctor answer
Depends on titer: A high titer result suggests an auto-immune disorder, but, there are many false positives. Any lab result needs to be interpreted in the context of clinical and other lab findings. Consult your doctor. ...Read more
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