Doctor insights on:
Positive Anti Dna Test
Hello. I have a positive double stranded DNA test result (anti-dna (ds) ab qn of 29 with positive being above 9. Ana is negative, what can this mean?
Abnormal tests: Best to discuss this question with the doctor ordering your tests.
Antinuclear ab: positive, speckled; titer to follow. Ana titer: 1:40 anti-dna (sle): < 4 iu/ml is this a positive blood test for sle?
Probably for lupus: Your question is a little vague, but I suspect you are referring to a test that is sometimes used to look for lupus. In lupus there are certain antibodies that are known as anti double stranded dna antibodies that target a protein in dna. This test looks for a specific auto-antibodies.
Do you need to be positive for BOTH ANA and ANTI DNA to be diagnosed with lupus? What is the criteria?
No: You can still have lupus if one, both or neither are positive. There are eleven diagnostic criteria. Goigle the topic and read it for yourself.See 1 more doctor answer
AntiDNA: Sometimes anti-smith antibodies are tested or other testing for lupus or a related disorder. It depends on your signs and symptoms. Biopsies are sometimes required. The connective disease family is extensive and overlaps occur. That is why I trust rheumatologists.
I have fibro and uctd/lupus. Am on lyrics and anti-mylarials. My titer is 1:80 and Anti-DNA (DS)Ab Qn is <1. Does that mean it's positive?
With a family history of lupus and 7 out of 11 symtoms, can you still have lupus if after 2 positive ANA and anti DNA you have a negitive result?
Yes: I agree with dr. Namey on this issue. I would not disregard the previously positive tests even if the current studies are negative. Have you seen a rheumatologist?See 2 more doctor answers
Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna (ss)igg ab qn (119)& c react protien (5.6) what are implications?
Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor.
Autoimmune diseases: Anti-dna antibodies, a blood test done when suspecting connective tissue diseases also known as autoimmune diseases (example: lupus). The body immune system makes antibodies to attack its own dna resulting in illness. Caution: blood test alone will not make the diagnosis. Typical symptoms plus test are needed for diagnosis.
What are implications anti-DNA ss (119) elevated c reactive, imuglobulin e (3215) and elevated SED rate?
Need more info: All lab results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your lab results are consistent with inflammation that may be due to allergy.
Autoimmunity: Sometimes, the immune system makes antibodies that attack your own tissues. This occurs in disorders such as lupus, rheumatoid arthritis, and others. Anti-dna antibodies are just one form of antibody that are seen in autoimmune disorders. A high level of anti-dna antibodies should be evaluated by an immunologist or rheumatologist.
Anti nuclear Ab: Briefly, anti dna antibodies are antinuclear antibodies that are used in the diagnosis of the autoimmune disease systemic lupus erythematosis, sle. There are antibodies against double stranded dna and single stranded dna. The former is useful in the case of sle. It is probably released from dying cells in a process that appears to be defective in this disease. This is fairly specific to sle.See 1 more doctor answer
Radioactivity: The farr assay is a radioimmunologic assay. It uses radiolabeled antigens to detect specific antibodies in serum. The antigens are allowed to react with the serum and then precipitated using a special reagent such as protein a sepharose beads. The bound radiolabeled immunoprecipitiate is commonly analzyed by gel electrophoresis.
Dr said ihave lupus. What does all of this mean my ANA direct was + my anti DNA 48 what does all this mean?
See details: Lupus is an autoimmune disease with many possible clinical manifestations I see you are already on Plaquenil (hydroxychloroquine) and Methotrexate which is often a very effective combination. The best thing you can do is by under the care of a rheumatologist and stay on your meds. It is always better to be preemptive with this disease.
Anti-DNA antibody: People with lupus develop abnormal substances in their blood called antibodies. These antibodies attack various organs of the body and cause the signs and symptoms of the disease. Anti-dna antibody is one such substance. The exact reason why people develop these antibodies is not known but there is often a genetic component (family history).
Anti-DNA antibodies: Simple blood tests can be performed to test for anti-dna antibodies. Usually the screen is started with a basic ANA test which can then be followed with more specific antibody testing to determine if a specific disease can be identified. Of course, symptoms must also correlate since we do not simply provide diagnosis based on lab findings.
My rheumatologist confirmed that I am + anti DNA antibodies but he will not confirm it as lupus, what else could it be?
Many things: 1. Positive antibodies can proceed the onset of disease. 2. It could be a false positive. 3. Low titers, especially if IgA can be seen in healthy populations. Accuracy also depends on the type of test that was used whether it was elisa or ria. No test in medicine is 100% and rheumatology tests are worse than most.See 1 more doctor answer