Positive ana test and cancer - Doctor answers

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If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

? anti dsDNA: You've probably already had these more basic tests: complete blood count, sedimentation rate, C-reactive protein, urinalysis & rheumatoid factor. It appears to me that the ANA results with slight positive anti-Smith may suggest lupus; you need an antibody to double-stranded DNA (anti dsDNA) which is very specific & somewhat sensitive for lupus. All this needs to be correlated by your doc/specialist ...Read more

Dr. Barry Rosen
4,341 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Does a positive ANA of 1;640 spec pattern suggest cancer if all other test are negative?

Does a positive ANA of 1;640 spec pattern suggest cancer if all other test are negative?

ANA: An ANA is not a diagnostic test for cancer. It has no reliabilty for screening cancer. It is estimated that about 30% of all patients will have false positive. Unless you have symptoms consistent with an autoimmune process, it is not a diagnostic test. ...Read more

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Can cervical cancer show in a positive ANA test?

Can cervical cancer show in a positive ANA test?

No. An ANA: Ani-nuclear antibody is a lupus test, and can be positive in other rheumatological diseases/ cervix cancer needs to be diagnosed by an internal pelvic exam and a biopsy. ...Read more

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If u had a early cdt lung blood test and out of six tests the mage4 was a little over cutoff and u are ANA positive 1:640 spec. Suggest cancer?

If u had a early cdt lung blood test and out of six tests the mage4 was a little over cutoff and u are ANA positive 1:640 spec. Suggest cancer?

Autoimmune: I can't say much about the earlycdt test- it is not primetime at this time. To me, the test has to go through validity and quality control first and there is no a good clinical trial that backed up this test- I won't use it at this time. If you don't know how to interprete the result-it only creates anxiety &unnecessary test. You may have autoimmune disease-especially if you have symptoms. D/w md. ...Read more

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I was just told I have an elevated positive ana level (1/80) should I be concerned about cancer?

No: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that an ANA of 1/80 in of itself is not worrisome. Do you have any symptoms? Were other tests done, if yes, what were the results. ANA is not a marker for cancer.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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Can a positive ANA mean cancer in the blood?

Can a positive ANA mean cancer in the blood?

No: A low-titer ANA usually means nothing. A higher titer is helpful in confirming the diagnosis of several common diseases including lupus and type I autoimmune hepatitis, but is not a cancer screen. ...Read more

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Could a positive ANA 1;640 be a sign of cancer speckled pattern?

Could a positive ANA 1;640 be a sign of cancer speckled pattern?

No: Usually it is a sign of autoimmune disease not cancer, it is a marker and it cannot be interpreted by itself without a clinical picture. ...Read more

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A positive ANA 1;640 with all other panels negative ran by rheum dr what could this be? Could it b cancer? Cbc ok. Metabolic ok. Urine ok.

Need more info: An ANA of 1:640 may mean several things, and occasionally may mean nothing. Why was the test ordered in the first place? Only after knowing your specific issues and the results of a physical exam can one make a decision if the ANA is important. ...Read more

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Does a high sed rate and low RBC indicate cancer? I do have positive ana/speckled 1;640. Upper back pain for one year. Mri ok

Probably not: The high ESR and anemia could be related to rhuematological problems. Need further information and evaluation to get the right diagnosis. ...Read more

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My ANA is positive and the speckled pattern is 1:160. Doesthat indicate cancer? My thyroid and other tests are fine.

My ANA is positive and the speckled pattern is 1:160. Doesthat indicate cancer? My thyroid and other tests are fine.

ANA titter: ANA is not a cancer marker. It is a test to help pinpoint rheumatologic conditions, rather. Taken by itself, ANA is not a strong predictor of any one disease state. It needs to be taken in the context of a work up. ...Read more

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If you tested positive for mage4 on a early cdt lung blood test and have +ana 1:640 and elevated sed. Clear chest CT and MRI spine ok. Cancer?

If you tested positive for mage4 on a early cdt lung blood test and have +ana 1:640 and elevated sed. Clear chest CT and MRI spine ok. Cancer?

Check with your doc: Mage4 on a early cdt lung blood test was ordered by a doc, although you do not seem to be a high risk patient and you probably do not smoke 3 packs daily. Therefore the test was not necessary and now we have false positive result.
You may have some form of lupus, or sle, or something else. I highly doubt that you have cancer. However, check with your doc to be safe. Ask why the test was necessary. ...Read more

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What does it mean to have a positive ANA blood test?

What does it mean to have a positive ANA blood test?

Nada without disease: If you do not have a clinical disease or symptoms then it simply means you have a positive test (maybe 1/3 of the population has a "positive" test). If the titer is very high (greater than 1:640) you should probably be followed to see if a disease is developing. ...Read more

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Ana test results question - how many people have ANA positive but don't ever get lupus?

Age and gender: Positive ANA test is commoner in older people and women. Up to 25% of the people may have positive ANA test at some time or the other. Only 0.1-0.15% of the population has systemic lupus. ...Read more

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Would a negative ANA rule out lymphoma? Does lymphoma cause a positive ANA test result?

It does not: At your age, if you have lymphoma it's probably Hodgkin's. ANA really has nothing to do with malignant lymphoma. If you're worried about big lymph nodest, trust me -- lymphoma nodes are obviously very abnormal. Best wishes, and I hope you'll always stay actively involved with your health. ...Read more

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Tomorrow, I have to do another ANA test, will me taking plaquinil cause a false positive ana?

No: Wondering why you are taking a medication often prescribed for lupus if you don't list either lupus or another reason for the medicine. Anti-nuclear antibody tests aren't reported as "positive" or "negative" but as a titer. They remain an important screening test for lupus. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more