Doctor insights on:
Positive Ana Genetic Marker
Can a positive ANA (going up for years, now 1/640) be insignificant if other autoimmune markers are negative?
Probably not: If you don't have symptoms but why are they checking it?? Ask the person who ordered it to be sure. They know you and your history . ...Read more
From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more
Started me on plaquenill due to symptoms (no dryness)low positive ana. He mentioned markers for sjogrens then he spoke of lupus.Gave no diagnose?
Ana positive 160 poss mtcd w/o lupus markers. What can cause 300 mg/dL lambda 200 lambda if no paraprotein? Check igd/e? Urine spot lambda bjp found
BJP: Bence Jones proteins, light chain, occur in multiple myeloma , lymphomas/chronic leukemias, monoclonal gammopathy of undetermined significance which can go on to myeloma at the rate of only 1%/yr -small risk),amylodosis,cryoglobunemia, Autoimmune disease can give false positive. Check IFE & bone marrow http://www.livestrong.com/article/372234-about-multiple-myeloma-and-bence-jones-protein/ ...Read more
What conditions may cause backpain, shoulder pain, ankle pain, joint pain along with weight gain, an elevated ALT (75 U/L), and ANA positive once.
Many explanations: This constellation of symptoms is very non specific and could be due to one of several processes. Inflammation/autoimmune disease, infection, trauma or overuse, obesity, metabolic problems, medication induced,genetic disorders, excessive alcohol intake, vitamin deficiency, particularly vitamin D. The best course of action is to see or talk with a doctor to explore possibilities. Wishing you well! ...Read more
Autoimmune disorder: Lupus or other autoimmune disorder a possibility. Those titre numbers (1:40) are not extremely elevated so it may also be a normal variant. Also other connective tissue disorders possible: polymyositis, rheumatoid, sjogren's, etc. You probably need additional blood work and to possibly see a rheumatologist. ...Read moreSee 1 more doctor answer
Yes.: This is relatively high as it had to be diluted by 320 times. So this means it was very concentrated. Labs vary on what their cutoff for positive ANA is, but in all likelihood, this would be considered positive or high. It might not mean anything though, as even healthy, unaffected people can have a positive result as can those with viral infections, medicated, and with cancer can have it. ...Read moreSee 1 more doctor answer
Antibodies vs nuclei: The titer (how much antibody power is present) is important -- 1:40 seldom means much, 1:320 would worry most folks -- as does the pattern, but like all lab tests, its meaning comes from the setting. Typically a screen for lupus and related diseases, many older folks who are healthy run a low titer. ...Read more
I recently got a positive ANA test 1:80 homogenous with no other symptoms. What does this mean? 32 yrs old healthy.
Positive ana: 1:80- not that high. Worry if > 1:160.Ana tests for autoimmune disease. In recent study ~13% of well blood donors had + ana with no symptoms, of those, 72% did not develop any issues with ~ 4 years of follow up. Sometimes other conditions like thyroiditis, mono, chronic disease,multiple sclerosis can cause positive ana as can meds :INH,hydralazine,procainamide remicade. FU with rheumatologist. ...Read more
I have a positive ANA test but it reads as 6? I'm used to seeing them as 1:40, 1:80 etc... What does 6 mean?
An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more
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