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Doctor insights on: Positive Ana And Elevated Sedimentation Rate

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If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

If I have a high positive ANA (1:640) speckled, nucleolar and low positive SMA (1:40), what further tests do I need to do? (Negative SS-A, SS-B, Smith, RNP, SCL-70, Anti Jo Abs)

? anti dsDNA: You've probably already had these more basic tests: complete blood count, sedimentation rate, C-reactive protein, urinalysis & rheumatoid factor. It appears to me that the ANA results with slight positive anti-Smith may suggest lupus; you need an antibody to double-stranded DNA (anti dsDNA) which is very specific & somewhat sensitive for lupus. All this needs to be correlated by your doc/specialist ...Read more

Sedimentation Rate (Definition)

Is the rate at which red blood cells sediment in a period of 1 hour. It is non-specific measure of inflammation. It is performed by placing anticoagulated blood sample in an upright tube (westergren tube) then measuring the rate at which red blood cells fall (in mm per hour). It is useful in diagnosis of some diseases, such as autoimmune diseases, for assessment of severity of ...Read more


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A positive ANA of 1:80 titer Nucleolar pattern, 36 RF, 22 Sedimentation rate and a 3.0 hsCRP...could this be something?

A positive ANA of 1:80 titer Nucleolar pattern, 36 RF, 22 Sedimentation rate and a 3.0 hsCRP...could this be something?

Nonspecific: This level of ANA is nonspecific but may be indicative of a mild autoimmune disorder but has to be interpreted in context of symptoms and physical findings. Your sed rate is not elevated and if you have no other findings, I doubt you have active inflammatory process going on. A rheumatologist is best qualified to evaluate and advise you about your status. ...Read more

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I have been tested with the following: sedimentation rate of 1, rf of <20, uric acid of 4.7 and a ANA speckled pattern of 1:160. Possible raynauds p?

I have been tested with the following: sedimentation rate of 1, rf of <20, uric acid of 4.7 and a ANA speckled pattern of 1:160. Possible raynauds p?

Raynaud's: Why were you tested? Raynaud's may not have any positive lab studies. If associated with scleroderma a scl 70 would likely be positive. A positive rnp would suggest mixed connective tissue disease. Raynaud's can also be unrelated to a connective tissue disease. Sometimes raynaud's is related to peripheral vascular disease. It can be a side effect of medications such as beta blockers. ...Read more

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I have been tested with the following: sedimentation rate of 1, rf of <20, uric acid of 4.7 and a ANA speckled pattern of 1:160. Possible raynauds p?

I have been tested with the following: sedimentation rate of 1, rf of <20, uric acid of 4.7 and a ANA speckled pattern of 1:160. Possible raynauds p?

Tip of the iceberg: You may well have raynaud's but this may just be a symptom of a larger picture. You may have something else as well. You need further testing to rule out a collagen vascular disease such as lupus or sjogrens. ...Read more

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What could cause chronic joint pain (most joints) in otherwise healthy 25 yo male? Rf, ana, treponema pallidum, sedimentation rate all normal.

What could cause chronic joint pain (most joints) in otherwise healthy 25 yo male? Rf, ana, treponema pallidum, sedimentation rate all normal.

Inflammation: Inflammation has many possible causes. There is the possibility of seronegative RA (ra test is negative); given that all of your tests are negative focus on nutritional causes. Stop all acid intake especially sodas; increase antioxidant intake and herbal antiinflammatories and a new product on the market that has been shown to reduce oxidative stress to near nothing. Www. Medacpc. Com for more. ...Read more

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Neck CT "small cortical defect along the anterior aspect of the dens just below the anterior arch of C1 with adjacent bone or calcific density." Platelets - 487. ANA is neg. RA Factor - neg. C-Reactive Prot, Quant - 79.6. Sedimentation Rate-West - 47?

Lab results: Hello ~ there is no history so impossible to comment. The CRP is non-specific and slightly up and ESR is non specific and slightly raised. Luckily the ANA and RA negative. The changes at ant ramus C2 and dens are nonspecific possibly due to osteo-arthritis. (ANA and RA shd not be routine labs!) If mets or myeloma in dd do bone scan. thanks ...Read more

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What is an elevated sedimentation rate?

What is an elevated sedimentation rate?

Marker of: Inflammation. Elevated ESR is a non-specific marker of inflammation, but not diagnostic of any particular disease. ...Read more

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Would active multiple sclerosis cause an elevated CRP or sedimentation rate?

Would active multiple sclerosis cause an elevated CRP or sedimentation rate?

ESR and cRP in MS.: Being multiple sclerosis is an inflammatory condition, it would not be unreasonable to think that the ESR and CRP could be elevated when the condition is active. That being said, ESR and CRP are very nonspecific markers and in and of themselves should not be used diagnostically in this context. ...Read more

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What to do about rheumatoid factor: 1"60 titer, elevated erythrocyte sedimentation rate what is the preliminary diagnoses?

What to do about rheumatoid factor: 1"60 titer, elevated erythrocyte sedimentation rate what is the preliminary diagnoses?

Not rheumatoid: This may not be rheumatoid arthritis. Other medical causes can be the reason. We need more information. Your physician can clarify this ...Read more

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I realise that these markers aren't specific but wouldn't most advanced cancers cause elevated Sedimentation rate and C-reactive protein?

I realise that these markers aren't specific but wouldn't most advanced cancers cause elevated Sedimentation rate and C-reactive protein?

No: Nice to be able to help once again, Matt. The sed rate and especially the C-reactive protein result from the liver pumping out extra large amounts of a couple of particular proteins that are stimulated by very particular things that are often produced in inflammation and seldom in pure neoplasia. Forget most (not all) of what you've read about "immune response to cancer" as myth. Best wishes. ...Read more

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Crp and sedimentation rate are both independant indicators of inflammation, do we know to what problems continuous and elevated sr (2xmax) only lead?

Crp and sedimentation rate are both independant indicators of inflammation, do we know to what problems continuous and elevated sr (2xmax) only lead?

Many causes Hi SR: The sedimentation rate (sed rate) blood test measures how quickly red blood cells (erythrocytes) settle in a test tube in one hour. The more red cells that fall to the bottom of the test tube in one hour, the higher the sed rate.

When inflammation is present in the body, certain proteins cause red blood cells to stick together and fall more quickly than normal to the bottom of the tube. These pro. ...Read more

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I recently got my blood report. I have c-reactive protein (c.R.P.) positive with 4.8 mg/dl & erythrocyte sedimentation rate 24 and packed cell volume 33?

I recently got my blood report. I have c-reactive protein (c.R.P.) positive with 4.8 mg/dl & erythrocyte sedimentation rate 24 and packed cell volume 33?

Inflammation: You are anemic and have inflammation. Check 25-oh vit d level. Anemia could be due to iron deficiency if having heavy periods. That can make you more toxic to cadmium a pollutant that is activated by stress and increases cr-protein. Improve health with healthy food, supplements to prevent deficiency, a good night sleep, mild exercise through the day, and de-stress. See kelly mcgonigal's book. ...Read more

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Emergency spinal surgery June 24. He still has elevated CRP at 117 and his sedimentation rate > 140. Mri friday. Typical? Pain 4/5 in back.

Emergency spinal surgery June 24. He still has elevated CRP at 117 and his sedimentation rate > 140. Mri friday. Typical? Pain 4/5 in back.

Both point 2 infecti: ...on. C Ur spinal surgeon now. MRI needed 2 investigate this. May B paraspinal abces (sp). These R serious elevations @ this long after surgery. ...Read more

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I have an elevated sedimentation rate, elevated white blood cell count, elevated absolute neutrophils, elevated absolute lymphocytes, & low iron level?

I have an elevated sedimentation rate, elevated white blood cell count, elevated absolute neutrophils, elevated absolute lymphocytes, & low iron level?

How do you FEEL?: If the white cell values are not extremely out of range, and all are well formed, I would not worry about them. Iron is more worrisome as even without anemia, low values can war of poor nutrition or bleeding from an uncertain or tumor. Nobody here can really tell you much more than that we are glad you are amtaking an active role in understanding your health. ...Read more

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Results showed that I had an sedimentation rate of 69. What can this mean?

Results showed that I had an sedimentation rate of 69. What can this mean?

See below: High sedimentation rates may be caused by:
autoimmune diseases, such as systemic lupus erythematosus or rheumatoid arthritis.
Cancer, such as lymphoma or multiple myeloma.
Chronic kidney disease.
Infection, such as pneumonia, pelvic inflammatory disease, or appendicitis.
Inflammation of joints (such as polymyalgia rheumatica) and blood vessels (such as giant cell arteritis). ...Read more

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Can having hayfever give you a longer sedimentation rate?

Can having hayfever give you a longer sedimentation rate?

No. Unless...: Not really, unless you have infectious sinusitis or brochitis from your allergies. By the way. A CRP is a better marker for inflammation. I rarely get esrs! ...Read more

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Can allergies affect your sedimentation rate?

Can allergies affect your sedimentation rate?

Should not: The sedimentation rate (ESR) is not diagnostic of any one disease but is increased in conditions with inflammation and necrosis (dying tissue). Esr is increased in collagen disease like lupus, infection (pneumonia, tb), tumors, heavy metal poisoning, heart attack, kidney diseases, anemia from chronic disease, arthritis conditions, gout, thyroid problems and more. It is not elevated in allergy. ...Read more

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Can have cancer and normal sedimentation rate?

Can have cancer and normal sedimentation rate?

Yes: The sedimentation rate is a notoriously non-useful test except in a very few situations. If you have any concern about cancer, please get checked properly. Good luck. ...Read more

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Erythrocyte sedimentation rate (esr) of 2! is this normal?

Yes.: The normal ranges are as follows:
< 50 yrs of age
men 0-15 mm/hour
women 0-20 mm/hour
> 50 yrs of age
men 0-20 mm/hour
women 0-30 mm/hour. ...Read more

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What could cause a low erythrocyte sedimentation rate (esr)?

What could cause a low erythrocyte sedimentation rate (esr)?

No low: Erythrocyte sedimentation rate (ESR) is used to measure inflammation. An abnormally higher number denotes a higher amount of systemic inflammation. There technically are no "low" sedimentation rates as the normal ESR range starts at 0 mm/hour. ...Read more

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What is the importance of esr= erythrocyte sedimentation rate?

What is the importance of esr= erythrocyte sedimentation rate?

Inflammation: Esr is an indicator of general inflammation. It can elevate for any number of reasons but typically during infection and flare-ups of rheumatic diseases such as arthritis. ...Read more

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Does a normal ESR/sedimentation rate rule out malignancy/tumor growth?

Does a normal ESR/sedimentation rate rule out malignancy/tumor growth?

No: ESR is not a rule in or rule out test. Meaning that having a high or low ESR does not mean it alone means anything for certain. It basically tests inflammation in the body. Sometimes tumor and malignancy cause inflammation, some other malignancies/tumors do not. Theses tests are not used to say you DO or DO NOT have a malignancy or tumor growing in your body. ...Read more

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What is wrong. My Sedimentation rate is 58.0 an my c reactive protein is 3.6?

What is wrong. My Sedimentation rate is 58.0 an my c reactive protein is 3.6?

More info needed: I'd like to help, but there are at least a hundred separate medical conditions that could cause these lab test abnormalities. It's not unlike asking the cause of a fever. The likely causes will depend on other symptoms, physical exam by a health professional, and other lab tests. If you're not under a doctor's care, call for an appointment ASAP. Some of the possible causes are serious. ...Read more

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What does this all mean? Low mchc and a high RDW low monocytes and a high sedimentation rate?

What does this all mean? Low mchc and a high RDW low monocytes and a high sedimentation rate?

Laboratory Results: This depends on what your physician is treating you for. These are not specific to anyone diagnosis. The MCHC and RDW are describing your red cell size. The monocytes are one type of cell you have floating in your bloodstream. The high sedimentation rate is seen in various types of inflammation. You physician will explain these as he or she proceeds to diagnose you and treat you ...Read more

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I Have a high sedimentation rate (significant inflammation). what's the next step for treatment and where to go?

I Have a high sedimentation rate (significant inflammation). what's the next step for treatment and where to go?

Inflammation: Has become widespread and is at the root of many illnesses. Please see your doctor for treatment. Also ask about natural approaches such as good quality marine fish oil and turmeric. Ask about an anti-inflammatory food plan also. Peace and good health. ...Read more

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What happens if ESR (erythrocyte sedimentation rate)is 80mm/hr in female what kind of disease she is suffering from.?

What happens if ESR (erythrocyte sedimentation rate)is 80mm/hr in female what kind of disease she is suffering from.?

Not a specific test: The sedimentation rate is not a specific diagnostic test for anything. It is often used to follow some diseases but not diagnostic by itself. It needs to be coupled with a complete history and physical exam and other diagnostic tests. ...Read more

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I have 549igA, 37 sedimentation rate westergren, 21.64 free kappa lt chains, s, and kappa/lambda ratio, s is 1.66 What does this mean?

I have 549igA, 37 sedimentation rate westergren, 21.64 free kappa lt chains, s, and kappa/lambda ratio, s is 1.66 What does this mean?

Any symptoms?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, Why were these tests done? Do you have any symptoms? Kappa/lambda ratio is generally a useless test. IgA of 549, per se is not a problem. Sed rate is in the normal range.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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What will a sedimentation rate show?

What will a sedimentation rate show?

Inflammation: ESR or erythrocyte sedimentation rate is a reflection of inflammation in the body. It is not a very specific test. It can be elevated in the setting of an infection, certain cancers, and many autoimmune/rheumatologic conditions. The last category includes conditions such as rheumatoid arthritis, vasculitis and lupus. Normal ESR is no higher than age/ 2 for men or age/ 2 plus 10 for women. ...Read more

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What is the clinical signs of increased sedimentation rate?

What is the clinical signs of increased sedimentation rate?

Reverse: Sedimentation rate is ordered when inflammatory condition or autoimmune disorder is suspected. This test is frequently ordered by rheumatologists. The list of conditions with elevated cr is long. Good luck with your homework! ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more