Doctor insights on:
Positive Ana And Elevated Esr
My daughter has joint pain but her joints arnt swollen and have positive ANA and elevated ESR leves. What could cause this?
An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more
My daughter has joint pain but her joints arnt swollen and have positive ANA and elevated ESR leves. Could this be jra?
I had a positive ana test elevated esr and crp, doctor told me it was nothing to worry about. Do I get a second opinion?
Never hurts to ask: If you are concerned about your health, getting a 2nd opinion is a good idea. After all it's YOUR health, not the doctors... and I always think it's important to listen to that 'inner voice'. There must be SOME reason your ESR and CRP are elevated. To me, as an infectious diseases doctor, I would really want to know. A thorough history and proper physical exam would be a basic starting point. ...Read more
I have a ANA positive result and elevated ESR 7 months ago along with joint pain/swelling that gradually gets worse, fatigue, cognitive issues. Normal CRP and CCP. No other reccomendations from Rheumatologist.?
More tests: Joint swelling and an elevated ESR indicate that you have joint inflammation, not just joint pain. This makes it suspicious for seronegative RA (rheumatoid arthritis with negative RF, negative CCP) or a disease in the lupus family. The ANA is not as helpful as you might think as it is positive in many conditions. However, you need DNA, ENA, complement testing now for diagnosis. You also need Rx. ...Read more
Many things: I'd ignore the normal ESR / sed rate. The ANA at this titer is concerning, but means nothing apart from its clinical context. Many women even of your age have positive ana's like this without evidence of illness. If it was ordered as part of a rheumatology workup, it suggests something in the autoimmune / lupus family. Despite the many labs, diagnosis and treatment rest mostly on clinical picture. ...Read more
I have weak positive ANA result and high ESR, But the RA test is negative. So, what does it mean and what care should I take?
Causes to results? HsCRP=9.4; ANA Positive (speckled); Low ESR; ENA Negative; dsDNA Negative; ssDNA Ab IgG - PENDING. Big Toes &, wrists pain
When lupus is being treated with plaquenil (hydroxychloroquine) does crp, ESR go down & does positive ANA turn negative?
My 6 yr old has had pain in her legs, feet and ankles for the past few months she has a positive ANA and a high ESR what can cause this?
I'm 25 fm with a 29 esr, ANA positive 1:80 speckled pattern, and RA was <10. joint inflammation issues, especially in my back, knees. Possibilities?
Several: But it will be better for you to consult a rheumatologist who will likely obtain additional tests to establish a diagnosis. ...Read more
If I'm ANA + aren't I ANA positive regardless of the ratio? Then add hlab27+ rf - ESR 25 inflam low back pain iritis and fatigue. Must be auto immune?
Likely yes,,: Your positive antibodies and a history of low back pain, iritis, and fatigue suggest an auto-immune disorder, most likely on the order of ankylosing spondylitis, which can give this presentation. The ANA may suggest something else also but may be due to the autoimmune nature of the spondylitis, as may the ESR which isn't particularly high but is elevated and can indicate temporal arteritis. ...Read more
I have an ANA positive, ESR 17, chromatin positive 6.7. Joint pain, fatigue, butterfly rash and fatigue. Is this lupus?
Sounds like it: I quacks like lupus but you really need the help of a rheumatologist to help you avoid damages to your organs. He is in the best position to make the diagnosis. ...Read more
Fast pulse, red blood cells little low, ESR high. Ana positive 1:640 speckled. Up back pain 1 yr blood in stool twice year or so. I do have hemroids?
See your doc: The symptoms you are giving warrant further wrork up. Hemorrhoid alone do not explain the high ESR and the fast pulse. It is important to know how high is the ESR and to do a complete physical exam to look for skin rash or mucosal ulcers. Only a physician can guide you to get an accurate diagnosis. ...Read more
After 50 mg prednisone for 5 days ESR (25) CRP (3.5) Are both slightly elevated? Ps. (ANA) has been positive for years
Stop worrying: As a pathologist, I'd consider that sed rate normal. CRP is really useful only as a sensitive screen so as not to miss folks with advanced atherosclerosis not yet symptomatic. I doubt it means anything here; just care for your vascular health. About 1 adult in 4 has a low-positive ANA. I'd ask for a full explanation from your physician as to why you were put on prednisone in the first place. ...Read more
Very possible: It does fit the lupus picture. That being said, discuss this diagnosis as well as other possibilities with your rheumatologist. ...Read more
All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that an ANA of 1/80 in of itself is not worrisome. Do you have any symptoms? Were other tests done, if yes, what were the results. ANA is not a marker for cancer.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more
Rough year. Ana positive 1;640 sed rate 30. When I visit the drs and randomly throughout day my temp is elevated off and on. Never over 99.9.?
Autoimmune disease: A positive ANA can occur in autoimmune disorders, which can affect many organs including joints, musculoskeletal system, kidneys, liver, salivary glands, thyroid and many more. A thorough work up with your internal medicine doctor and appropriate specialist may be needed. The sed rate and fevers may all be related to the inflammation associated with possible autoimmune disorders. ...Read more
I have had up back pain for one year in right shouldr. Temp daily is like 99.2-99.3. I am ANA positive 1:640with elevated sed. Temp a concern? Mri ok
I have a positive ANA 1:640 homogenous nuclear staining. Does this mean scleroderma or lupus? I also have a very slightly elevated angiotensin conv en
Depends: No diagnosis can be firmly established with a single blood test even in your case. Bone pain is not the usual manifestation of an autoimmune disease. Why was the test ordered in the first place? If your doctor suspects the presence of an autoimmune disorder, more tests will be needed to pin down the diagnosis. ...Read more
I have a positive ANA titer 1:80 nuclear...And elevated C4 @ 76. I have fsgs, no diabetes and moderate hypertension. What does this mean?!
No disease probably: A woman at age 50 may have a low titer ANA without any disease to go with it. Primary fsgs is not associated with positive ana. An elevated C4 is an "acute phase reactant", meaning a protein that can be increased with a variety of diseases. Acute lupus erythematosus is associated with decreased c4. Moderate hypertension and elevated glucose do not explain the findings. ...Read more
High positive ANA for years and now tested elevated complement C4 and C3 but all other autoimmune antibodies are still negative. What could that be?
Inflammation: Complement is a phase reactant which means it will go up with any type of inflammation. It is not specific for any one problem. A low complement is of more concern. These lab texts could mean you will eventually develop an autoimmune disease or other disease process associated with ANA. They slso may never amount to anything. ...Read more
If a lupus panel was negative and awaiting serum electrophise test what would that tell? My sed rate is elevated and ANA positive w/ speckled pattern
Nothing specific: These findings are not specific. This will depend on your total evaluation and why these tests being done. The test alone do not make a diagnosis. ...Read more
Could celiac disease cause ANA positive 1:640 spec pattern and elevated sed. Lupus neg. Serum protein normal?
No!: No it would not.Get a more detailed answer ›
Symptoms fatigue / headaches/ malaise. Work up 2008 negative except elevated CRP now elevated CRP 2.73, sed rate 22, ANA positive speck 1:40, ch50>60?
That's good: I would urge you to draw no conclusion from any sed rate reading that's not extremely high unless there's specific symptoms and signs. Millions of healthy young adults have positive ANA at a titer of 1:40 speckled. I'd urge you to get into a fitness-focused lifestyle, hang out with quality friends and do meaningful things. Best wishes. ...Read more
Infection: While there can be other possible causes, infection would be most likely to cause all of these abnormalities at once. ...Read more
Could you tell me what is the likely medical condition with elevated platelets wbc, sed rate positive ANA and anemia?
Not Enough info:
Each abnormal results will give you their own differentials. That means too many to list here.
Infectious or autoimmune diseases need to be ruled in or out asp.
Not enough information to comment on the anemia.
You need to follow up with your doctor for further work up and treatment without delay. ...Read more
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