Doctor insights on:
Porcine Pancreatic Lipase
Are pancreatic enzymes (amylase and lipase) always elevated if pancreatic cancer is present?? What about insulin blood level?
Insulin levels /P.Ca: Serum amylase and/or lipase levels: Elevated in less than 50% of patients with resectable pancreatic cancers and in only 25% of patients with unresectable tumors. Tumor markers such as CA 19-9 antigen and CEA: 75-85% have elevated CA 19-9 levels; 40-45% have elevated CEA levels.The odds of getting pancreatic cancer were worse for men with type 2 diabetes and the highest insulin levels. ...Read moreSee 1 more doctor answer
Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more
I have elevated liver enzyme ast(sgot)412 ALT (sgpt) 317 GGT 186 dilation of the common bile duct 1 CM no gallbladder?
Liver issue: Enzymes ast and alt are inside liver cells. When liver is injured by disease or medication, enzymes leak out, resulting in elevation. Can be due to many reasons, including medications like statins. An elevated GGT suggest biliary problems, but is not that specific. The normal common bile duct measures less than 0.8 cm, but after the gb is removed, can be 1cm. Complete history needed for this. ...Read moreSee 1 more doctor answer
Which test is better for diagnosing pancreas insufficiency: stool panc elastase or serum lipase/amylase? Would either diagnose pancreatic cancer?
Both together: Neither of the tests alone tells much. A combination of tests and exams will lead to diagnosis. Pancreatic cancer is not able to be ruled out by any test or imaging study. It can only be absolutely proven by some form of biopsy. A ct guided needle or egd with brushing a may be the only way to find it. ...Read more
Short answer: No: Most often if a malignant mass presses on the ductal system of liver or panc. (see picture), it can cause abn. blood enzymes. If the mass is small and ducts drain, routine enzymes are usually normal. Gilbert Syndrome, a genetic abn. of up to 7% of folks, has the significance like your fingerprints, and is discussed nicely in: http://ghr.nlm.nih.gov/condition/gilbert-syndrome ...Read more
NOT VERY!!!: Hi. Pancreatic polypeptide (PP) is NOT a screening test for pancreatic tumors. The only pancreatic cells that make PP are rare neuroendocrine cells in the Islets of Langerhans (an already tiny fraction of the pancreas). And those would be a TINY, TINY fraction of all pancreatic tumors. But hey, if it's a PP secreting neuroendocrine tumor of the pancreas, you'd have it dialed! Good luck! ...Read moreSee 1 more doctor answer
History & physical: If the pancreas is inflamed or damaged, amylase and lipase are often up, and it's not subtle. If your pancreas isn't functioning properly, you'll be losing weight with no explanation and probably have diarrhea / steatorrhea. Your physician can check your stool for pancreatic enzymes. It's rare but with a suggestive history, a screen may show something that could respond to enzyme replacement. ...Read more
Cure varies: Beyond the obvious differences in organ and cell type as well as the various treatment approaches, the most important patient difference is really the chance at cure. Early stage prostate and renal cell (kidney) cancers can be very curable. Even really early stage pancreatic cancers can be quite deadly. ...Read moreSee 1 more doctor answer
Gall bladder removed coz of gallstones. No alcohol. Liver function tests all normal. 2 GGT tests- 89, 124 IU/L. Bile duct disease? Need liver scan?
Normal pancreatic enzymes, normal liver enzymes, normal CBC, normal ESR & C-RP. does this rule out pancreatic and liver cancer?
Why do you ask?: Why would you think you have this stuff at age 20? You've written about this before. You owe it to yourself and those who love you to get with someone who can help you out these thoughts out of your mind and get on with studying, getting job skills and experience, perhaps finding romance and meaningful things to enjoy. To be brave, act brave. You're anything but helpless. ...Read more
Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?
No, just description: Like most dx, just a label for a pattern, as judged by whatever metrics. Yes, there is observed relation between fatty liver ; developing liver cancer. Fatty liver most commonly due to persistent low-fat, hi-carb (i.e. All sugars, simple ; complex) foods. Liver, to protect rest of body from ?sugar (toxic), converts sugars into triglyceride fats. If can't export into external fat, then fatty liver. ...Read more
They may: It is not unusual for patients to have slight elevations in their liver enzymes with gall stones. This is probably caused by sub clinical inflammation in the gall bladder. Significant elevations are seen in acute cholecystitis and elevation of the bilirubin can be due due common duct stones with obstruction. ...Read more
Pancreatic cancer?I had a pancreatic protocol ct/hida/liver, pancreas, CBC blood test/stool test/colonoscopy.All perfect.I still have light/yellow stool
Stop worrying: You have nothing to worry about except that fact that you are still a smoker, which i hope you'll stop. If everybody with light-colored stools consumed health-care dollars searching for pancreatic cancer, it'd be a huge waste. Evidently you're not even jaundiced. Please stop reading internet scare stuff, look for another cause of your abdominal pain ; stop reading internet scare stuff. ...Read more
Trypsin: Protease is a general term of any enzyme that breaks down proteins and includes, trypsin, and chymotrypsin. ...Read more
Mom has jaundice w elevated liver enzymes, and elevated amylase and lipase. Ct w contrast was done, no tumors seen. Could this be pancreatic cancer?
It is unclear: Hi kitten40047. The jaundice and elevated enzymes are concerning. It is reassuring to hear that the ct was negative. There may be other reasons for her symptoms. However, in the absence of any other explanation for the symptoms she has, you may want to have mom undergo additional tests, including perhaps MRI or endoscopy, which may shed more light on the pancreatic and liver areas. ...Read more
Elevated lipase/amylase, no gallbladder, mrcp no infl of pancreas, liver lesion, not a drinker/smoker, only 32, was taking asacol (mesalamine) hd/colazal, opinion?
Gallstone, 31% EF, low total bilirubin, high anion gap, hx of elevated liver enzymes. Liver enzymes leveled out after taking hormones.causes? advice?
HF: you have complex issues. Why do you have HF and also the cause of liver disease ? The AGMA is concerning and has to be worked up. Some of these conditions can be related. What hormones did you take ? I have more questions than answers, more so because you have 2 organ dysfunction and a acid base disorder and they can be related. ...Read more
Age 36, no alcohol. Bilirubin 4 sgpt 127 sgot 79 liver size 14.5cm. Diffuse fatty liver. No biliary dilatation. Common duct 2mm. Confirm fatty liver?
Lfts worsening-serum gammagt level 647u/l, serum alk phosphate 654u/l.Othr blood/heps normal.Mri &scans done. 3polyps large14mm in gallbladder-remove?
See specialist: The elevation in ggtp and alkaline phosphatase in the setting of gallbladder polyps that large mandates that you see a liver specialist before embarking on surgery. There are two types of specialists you should see, a hepatologist, a liver internal medicine doctor to make sure this is not some type of hepatitis or liver disease and then a liver surgeon to decide if the polyp is cancerous. Do asap. ...Read moreSee 1 more doctor answer
Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more
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