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Doctor insights on: Poor Corticomedullary Differentiation Kidneys

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Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


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If both kidneys r normal in size and reveal raised cortical echigenicity wid moderately reduced CM differentiation..Rs 9.7*3.7 & ls10*3.2cm.Is it risk?

If both kidneys r normal in size and reveal raised cortical echigenicity wid moderately reduced CM differentiation..Rs 9.7*3.7 & ls10*3.2cm.Is it risk?

Renal Echogenicity: The findings on your ultrasound are interpreted by a radiologist, they can suggest kidney disease and cannot diagnose its extent. You should see a nephrologist and have a 24 hour urine for creatinine clearance (cc) and protein and have some blood taken when you return the urine. That will give you a precise picture of what your kidney function is. Interpretations are subjective, a cc is objective. ...Read more

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A multifocal area of loss of cortical meduillary differentiation was noted in my kidneys suggestive of pyelonephritis. What is this?

A multifocal area of loss of cortical meduillary differentiation was noted in my kidneys suggestive of pyelonephritis.  What is this?

Pyelonephritis: If you are asking what pyelonephritis is, it is due to inflammation of one or more parts of the kidney. Generally it is due to a bacterial infection. If someone told you that you had pyelo. you should be treated for it with antimicrobial treatment. You should have a urine culture to determine the bacterial type and susceptibility patterns. This is serious stuff, get it taken care of. ...Read more

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Kidney ultrasound show increased cortical echogenicity (right >left) with mild loss of corticomedullary differantiation. Advice: kft correlation.Mean?

Kidney ultrasound show increased cortical echogenicity (right >left) with mild loss of corticomedullary differantiation. Advice: kft correlation.Mean?

Correlate blood test: Increased cortical echogenicity with mild corticomedullary differentiation, usually means medical renal disease. Kft probably means kidney function tests. These are blood tests such as serum creatinine, bun, and GFR (glomerular filtration rate). ...Read more

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Non-contrast CT report said increased density corticomedullary junction bilateral kidneys-suspect for tiny renal caluculi. Should i worry?

Non-contrast CT report said increased density corticomedullary junction bilateral kidneys-suspect for tiny renal caluculi. Should i worry?

Let me explain: If the stone is the problem, i think this not a major issue, the stone some time could go down by itself or by using (lithotripsy technique).
I would recommend you take of it ...Read more

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What is the definition or description of: differentiated?

What is the definition or description of: differentiated?

See below: The process by which cells become progressively more specialized; a normal process through which cells mature. This process of specialization for the cell comes at the expense of its breadth of potential. Stem cells can, for example, differentiate into secretory cells in the intestine. ...Read more

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What is adenocarcinoma, moderately differentiated mean?

It is cancer: Adenocarcinoma is a cancer that originates from glandular epithelial cells. This is usually classified as poorly, moderately or well differentiated based on the resemblance of these cells to normal epithelium with the well-differentiated cells being most similar in appearance to the normal cells. The poorer the differentiation, the more aggressive and poorer prognosis. ...Read more

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What is differentiated adenocarcinoma endometrium?

What is differentiated adenocarcinoma endometrium?

Cancer of the uterus: This is a medical expression used when doctors report a diagnosis of Cancer of the Uterus lining(endometrium).
Your gynecologist can explain further, so call him/her up ASAP and ask how to get this disease treated soon. ...Read more

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Can you tell me how are adult stem cells differentiated?

Can you tell me how are adult stem cells differentiated?

I wish I knew!: The process is an active area of investigation. If I knew how to make adult stem cells into beta cells, that could cure diabetes. Same would apply to many other diseases. ...Read more

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How are pancytopenia and myelodysplastic syndrome differentiated?

How are pancytopenia and myelodysplastic syndrome differentiated?

Bone Marrow Biopsy: Pancytopenia is a clinical condition that can be caused by a variety of diseases such as aplastic anemia, myelodysplasia, drug toxicity. Myelodysplasia is a clinical syndrome that may manifest itself as pancytopenia. A bone marrow biopsy is the only way to tell what is going on. ...Read more

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How is acute clot differentiated from chronic clot on ultrasound?

How is acute clot differentiated from chronic clot on ultrasound?

Several ways: There are a number of features that can be used to distinguish acute from chronic venous thrombosis.

In acute clot the lumen of the vein will be hypoechoic. The vessel will be enlarged and there may be peri-venous edema.

I chronic clot the intraluminal echoes will be hyperchoic. There may be evidence of recanalization. The vein may be contracted. ...Read more

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Is it possible for differentiated endometrioid adenocarcinoma to be cured?

Yes: endometrial cancer which begins in the endometrial mucosa, before invading myometrium or muscle of uterus is virtually 100% cureable. Even if D&C shows tumor cells spreading to blood stream this is not metastasis but cells pushed by curettage into the blood. Even early muscle invasion followed by hysterectomy with node diss. can be cured. ...Read more

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How is mast cell activation syndrome diagnostically differentiated from carcinoid syndrome?

How is mast cell activation syndrome diagnostically differentiated from carcinoid syndrome?

Totally different: The chemical mediators for these two conditions are totally different even though both can cause flushing. MCAS can be diagnosed by a blood test, carcinoid usually a urine test. ...Read more

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Can you tell me how terminal differentiation of chondrocytes effect the healing of cartilage?

Can you tell me how terminal differentiation of chondrocytes effect the healing of cartilage?

Homework: Physicians are not in the habit of doing patients homework for them. It would be inappropriate for you to use any answers here as your own. Perhaps reading the chapter and then answering the questions in your own words would be wise. ...Read more

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What are the advantages/disadvantages of imiqunoid vs surgical excision to treat differentiated VIN 2?

What are the advantages/disadvantages of imiqunoid vs surgical excision to treat differentiated VIN 2?

Imiquimod 5%: offers a noninvasive treatment for VIN. A major advantage over the potential scarring, deformity, and/or recovery from surgery. It provides complete resolution in ~75% cases. There is a ~25% risk of disease recurrence. Imiquimod works by prompting your immune system to fight the cancer. The inflammatory response to imiquimod can result in topical side effects, requiring breaks in treatment. ...Read more

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What's the option for a patient diagnosed with poorly differentiated adenocarcinomas with mixed inflammation?

Options for Cancer: Need more information, such as where is it located (adenocarcinomas can be in many different organs), is there lymph node involvement, etc Important to remember that there is alway more than one option or approach, including choosing not to treat. Talk it over thoroughly with your oncologist, ask lots of questions, have someone with you to take notes, get 2nd (and 3rd) opinions if necessary. GL ...Read more

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How are diagnoses of lysosome storage disorders differentiated from congenital disorders of glycosylation? References?

How are diagnoses of lysosome storage disorders differentiated from congenital disorders of glycosylation? References?

Difficult to differe: Lysosome storage disease, congenital disorders of glycosylation (cdg), peroxisomal disorders, smith-lemli-opitz are "single-gene disorders, most of which demonstrate autosomal-recessive inheritance. These 4 categories of metabolic diseases involve molecules important in cell membranes and share overlapping clinical presentations". (avery's diseases of the newborn, by w. Taeusch, 2005, p. 258). ...Read more

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What is the difference between cancer in situ and differentiated VIN3? What is the long term prognosis? VIN3 twice in 12 months with clear margins

What is the difference between cancer in situ and differentiated VIN3?  What is the long term prognosis? VIN3 twice in 12 months with clear margins

VIN3 = appearance of: cells under microscope, judged to be most abnormal, "pre-cancerous appearing" yet not clearly cancerous; see: https://www.google.com/#q=VIN3. Cancer in situ simply means no other sites (metastasis) of similar cells have been identified/recognized to be present. The 2 key definitions of cancer are: (1) Invading adjacent normal cells &/or (2) also growing in other parts of body (metastasis). ...Read more

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Will a moderate stroke from 1.5 years ago still show on an MRI?And do "old old" damage and newer old damage look alike, or can they be differentiated?

Will a moderate stroke from 1.5 years ago still show on an MRI?And do "old old" damage and newer old damage look alike, or can they be differentiated?

Stroke and MRI: New strokes look different on an MRI (depending on the type and stage / swelling / bleeding ) The best way to distinguish the difference is to compare to a previous study. Clinical assessment may not always inform you what has transpired as many strokes are clinically silent. ...Read more

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What is the likelihood of DIFFERENTIATEZD VIN to progress to cancer? Is differentiated VIN 2 more likely to progress to cancer than undifferentiated?

What is the likelihood of DIFFERENTIATEZD VIN to progress to cancer?  Is differentiated VIN 2 more likely to progress to cancer than undifferentiated?

No: The chance of VIN 2 progressing to cancer is small. However, regular check ups as recommended by your GYN are essential.
Differentiated lesions are less aggressive and hence less likely to progress to cancer ...Read more

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Is measles differentiated from other illnesses?

Is measles differentiated from other illnesses?

Pattern or test: There are blood tests to differentiate the presence of the measles virus & antibodies from other infections. There is also the fall back to pattern of illness. Measles has some distinctive physical findings that differ from other illnesses & a trained observer can often make the diagnosis based on these findings. ...Read more

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What is the differentiation between free weight and machines?

What is the differentiation between free weight and machines?

Safety: if you are new to weight lifting i would recommend speaking with a certified personal trainer first to prevent injury. machines are designed to promote proper technique. free weights, like dumbbells and barbells activate more muscles, but put you at greater risk of injury. I personally like to use high quality resistance bands. ...Read more

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What is the differentiation between pure and non pure cocaine?

What is the differentiation between pure and non pure cocaine?

Cocaine pure/mpure: Cocaine in its purest form is a white, pearly product. Cocaine appearing in powder form is a salt, typically cocaine HCL. Street market cocaine is frequently adulterated or “cut” with various powdery fillers to increase its wt; the substances used in process are baking soda; sugars--lactose, dextrose, inositol, & mannitol; & local anesthetic. Pure C disolves in sulfuric acid with no coloration. ...Read more

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What is the best treatment for color differentiation difficulties?

What is the best treatment for color differentiation difficulties?

Depends: Tooth whitening is the first non-invasive choice. You can selectively whiten darker teeth if you want. Stay away from the one hour in office whitening as it is the least effective, most expensive, most side effects. And the light used with it has no effect. In my office we also offer internal bleaching if root canal treated teeth. As a last resort porcelain veneers can be done. ...Read more

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Is differentiated or undifferentiated VIN more likely to become cancer?

Is differentiated or undifferentiated VIN more likely to become cancer?

Both need Rx: Differentiated is clearly squamous, undifferentiated a more primitive type of cell. Both need to be managed, and both may be quite ugly cytologically (high risk) or relatively tame-looking. The pathologist can offer some guidance as to whether close observation / repeat biopsies might be appropriate. ...Read more

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Can you tell me about woman is the default in fetuses, sexual differentiation opts for female sex?

Can you tell me about woman is the default in fetuses, sexual differentiation opts for female sex?

Inducer substance: The inducer substance is only active if a Y chromosome is present at the time of embryo development when it causes differentiation into a male child. Without it, the "default menu" always "boots" to female. ...Read more