Doctor insights on:
Yes: Requires surgery. True fap is almost uniformly fatal by age 50. ...Read more
Autosomal dominant: Enter omim in your browser and go to the database of all inherited diseases. Autosomal dominant means that affected individuals have one normal and one abnormal gene copy, the abnormal one dominating to cause disease. An affected person has a 50% chance to pass on the abnormal gene and fap with each pregnancy. ...Read more
Autosomal Dominant: Fap is inherited in an autosomal dominant fashion. This means that if one parent has the gene, and the other parent doesn't, each child has a 50% chance of receiving the gene for fap. The disease causes hundreds of polyps to form in the colon (see the picture), leading to colon cancer. ...Read more
What is hereditary non-polyposis colorectal cancer (hnpcc) vs familial adenomatous polyposis (fap)?
Both inherited: In fap presents as colonic polyps ( gardners syn will have other tumors ) , autosomal recessive due to mutations in gate keeper, tumor suppres gene. On the contrary hnpcc or lynch syndrome. Is autosomal dominant, due to dna mismatch in repair, associated with other cancers of stomach, endomet. Ca, ovary, brain, skin etc. ...Read more
What does colonic mucosa with focal glandular atypia suggestive of diminutive, early adenomatous polyp mean?
Not cancer: The description you gave is not a cause for any concern. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more
Pre-cancerous: As opposed to a hyperplastic polyp, an adenomatous polyp is the type of growth in your colon that can become cancerous over time. Variants such as villous or tubulo-villous adenomas may also describe this type of polyp. If you have these removed at colonoscopy, you will require surveillance on a regular basis. ...Read moreSee 1 more doctor answer
BIOPSY RESULT SUGGESTIVE OF NONNECROTIZING GRANULOMATOUS INFLAMMATION NO PHENOTYPICALLY ABNORMAL LYMPHOID POPULATION DETECTED WHAT DOES IT MEAN?
Chronic inflammation: The tissue provided to the pathologist showed chronic inflammation. No cancer was seen. The biopsy was not diagnostic of a particular disease. Biopsy results need to be interpreted in association with rest of your medical history, symptoms, signs, and other tests and imaging studies. ...Read more
Not really: lynch syndrome is an inherited disease that will cause polyps that will led to camper Tubular adenoidal is a condition cam happen with or without lynch syndrome ...Read more
What percentage of lynch syndrome patients develop colon polyps by age 60? Not cancer but just polyps
Colon ca, not polyps: Lynch syndrome affects a minority of patients, as it is a rare condition that is often inherited (in about 30% of pts). Of these pts, about 70% will develop colon cancer - most of them by age 60. The risk is high. But the syndrome causes NON-polyp colon cancer, not polyps. It usually requires colon removal (colectomy) to reduce risk. Use HealthTap Prime or talk to your gastroenterologist about sym ...Read more
Your doctor can expl: The doctor who gave you this report must explain it to you, if you ask. It basically means that there is an ulcer in this lesion in your colon, where the cell are very active(proliferating). This may be a benign polyp, yet you need to get it removed as anything which is proliferating can turn into a cancer if you leave it alone inside for too long. ...Read more
For what reason colon part is usually prone to cancer in hnpcc (hereditary hereditary nonpolyposis colorectal cancer)?
Good sample: That is just pathologist speak for a good cervical sample. No worries ...Read more
Yes and no: All benign and malignant tumors result from accumulated genetic mutations. There are a few hereditary illnesses in which a child inherits a first mutation in the series that leads to colon cancer. However, most people with colon cancer began life with a genome free of cancer-causing mutations. Benign polyps may or may not acquire additional mutations and turn cancerous. ...Read more
Father65,biopsy result of nasal polyps- Moderately differentiated infiltrating keratinizing squamous cell carcinoma with areas vasaloid. is it cancer?
Multifactorial: Skin cancer, like most cancers, has many different things which affect it. In the case of skin cancer, lifestyle choices like high amounts of sun exposure and smoking will increase your risk for skin cancer. If you are at higher risk for skin cancer, discuss with your doctor and/or see a dermatologist for screening examinations. ...Read moreSee 1 more doctor answer