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Doctor insights on: Polymyositis Dermatomyositis Antibody Panel

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What are dermatomyositis, polymyositis and inclusion body myositis?

What are dermatomyositis, polymyositis and inclusion body myositis?

Separate myosotis: Each is a specific type of inflammatory muscle disease. We call this myositis because the muscles can show information. When you have this you need an extensive evaluation looking for other associated issues. Therapy will be different for each of these. ...Read more

Dr. Gerald Byrne
127 Doctors shared insights

Polymyositis (Definition)

Polymyositis is inflammation of the muscles. It is considered an autoimmune disease and which ones on inflammatory cells targeted their activity against muscle cells. This may be associated with fatigue and muscle weakness. There are several treatment options routinely use by a rheumatologists. I'm happy to do ...Read more


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What are polymyositis and dermatomyositis?

What are polymyositis and dermatomyositis?

Muscle inflammation: Both conditions are fundamentally a reaction of the immune system that generates inflammation within the body's muscles. The main difference between dermatomyositis and polymyositis is that dermatomyositis has a unique rash but in most other clinical areas they have a rather close similarity to each other. ...Read more

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Where can I do to get treated for polymyositis?

Where can I do to get treated for polymyositis?

Rheumatologist: See a rheumatologist or neuromuscular specialist. First to confirm that this indeed is the right diagnosis, and second, to evaluate the needs for medicines. Immunosuppressives are used to control disease activity. ...Read more

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Where are some of the best treatments available for polymyositis?

Local rheumatolgist: Polymyositis is an autoimmune muscle disease that left untreated can cause severe muscle weakness and atrophy of skeletal and involuntary smooth muscles. Treatment begins with cortisone and can advance to include oral immunosuppressive and newer intravenous immunosuppressive and biologic medicines all of which are availabe in the doctor's office or hospital. Physical therapy is critical. ...Read more

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Polymyositis life expectancy with sjogren's syndrome? What is prognosis?

Polymyositis life expectancy with sjogren's syndrome? What is prognosis?

Depends: On the course of the disease, organ involvement, baseline health status, the aggressiveness of the condition, and many other factors (response to treatment, etc.). ...Read more

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What defining difference exists between polymyositis and inclusion body myositis?

Different diseases: Both are muscle diseases that are difficult to treat, polymyositis tending to affect shoulders and hips, inclusion body mysoitis the forearms. Polymyositis is the more treatable, but the more likely to become very serious, we know something of its cause unlike inclusion body myositis. Under the microscope they look different. Both are difficult and I wish you good luck and courage. ...Read more

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What can I do to address juvenile dermatomyositis?

What can I do to address juvenile dermatomyositis?

Several Rxs': I believe the concomitant use of modest dose steroids and Methotrexate works best. When the mtx kicks in, you can begin a quicker tapering of the steroids. ...Read more

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How do dermatomyositis and arthritis differ? How are they similar?

Different: Dermatomyositis is a condition that causes muscle and skin problems. Symptoms include rash, skin changes/discolorations, muscle weakness, fatigue, and muscle pain. Arthritis is a generic term that refers to joint inflammation. It does not usually affect muscle or skin, and typically causes joint pain, stiffness, and sometimes deformity. They are treated differently. A rheumatologist can help. ...Read more

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Could you please tell me where is the best treatment available for polymyositis?

See details: The initial therapy is prednisone. Depending on response and severity of disease, other meds are often added. These include methotrexate, azathioprine, IV gamma globulin and biologics such as Rituxan (rituximab) among others. ...Read more

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Is cellcept (mycophenolate mofetil) a drug prescribed to treat dermatomyositis?

Yes: Cellcept (mycophenolate mofetil) is an immunosuppressant drug used to treat a variety if conditions. In rheumatology it is most commonly used to treat certain types of lupus. Cellcept (mycophenolate mofetil) has been used successfully to treat dermatomyositis. It can help lower and or eliminate the steroid dose. ...Read more

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Can dermatomyositis cause blurry vision?

Can dermatomyositis cause blurry vision?

No: Dermatomyositis is a condition of the skin and muscles with a particular rash and muscle weakness. Blurry vision is not typically associated with dermatomyositis. ...Read more

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How common is having dermatomyositis and scleroderma and what is the best treatment?

How common is having dermatomyositis and scleroderma and what is the best treatment?

Uncommon: These are uncommon diseases but inflammatory muscle disease can be seen with scleroderma like skin changes in mixed connective tissue disease, anti-synthetase syndrome and sometimes as a complication of scleroderma. ...Read more

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Can dermatomyositis patients have a healthy pregnancy?

Yes: Pregnancy in dermatomyositis is unusal and needs careful followup with high risk ob. It depends on the manifestations and how well it is controlled. In some settings pregnancy is not advised. ...Read more

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I think I have a rare auto immune disease called juvenile dermatomyositis. Can someone tell me what this is?

Different in adults: Dermatomyositis can be a very severe disease causing muscle damage and chronic rashes (months to years). However, in adults there is a risk for more serious disease. If you think you may have dermatomyositis, please discuss this with your doctor. Some simple tests and a good physical exam should help decide. ...Read more

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How do you r/o lupus (sle & discoid), fibromylagia, polymyositis, and sjogren's syndrome from each other? What other tests can we do?

Too complicated.: These diseases are difficult to distinguish at times and often require observation and repeated testing over time. The biggest clue is the clinical symptoms and lab testing provides confirmatory support. If you do not have significant symptoms, there may not be any more testing you need to do at this time. ...Read more

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Diagnosed w/Dermatomyositis last year, then Tumid Lupus and Raynaud's. Was just diagnosed w/Dysphagia. How does that change the general prognosis?

Diagnosed w/Dermatomyositis last year, then Tumid Lupus and Raynaud's. Was just diagnosed w/Dysphagia. How does that change the general prognosis?

See details: I am not certain it does change anything as you give no specifics about The severity of the dysphagia, current and past treatments and muscle enzyme levels. With your other manifestations are you certain you do not have mixed connective tissue disorder? ...Read more

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DX w/Dermatomyositis 18 months ago @ 31. Dysphagia and short of breath started about 4 months ago. What's my best, educated prognosis/survival rates?

DX w/Dermatomyositis 18 months ago @ 31. Dysphagia and short of breath started about 4 months ago. What's my best, educated prognosis/survival rates?

Learn more: Nobody here can give you betting odds without knowing your full history. The inflammatory myopathies can run with pulmonary fibrosis or your shortness of breath may have a different cause. You'd do best to become an expert on your illness -- a true pro-active patient who reads the real scientific literature. It's best for you and your physicians. Try to get into a research study. Best wishes. ...Read more

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My husband may have polymyositis, can this be treated and will he get back to normal. He cannot take Corticosteroids because of chronic kidney disease?

Auto immune disease: Polymyositis belongs to a class of illnesses known as auto immune. Other diseases in this category include lupus erythematosis, and rheumatoid arthritis. The order of business is first to make a diagnosis which includes a good history and physical as well as lab and xray. There are treatments Best to call a rheumatologist ...Read more

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Safe to use chemotherapy be used to treat polymyositis?

Safe to use chemotherapy be used to treat polymyositis?

Depends on severity: Steroids are the mainstay of treatment but have short and long term side effects this must be weighed against how well the ttreatment controls the disease the " chemotherapy " is the second line drugs used to control the disease if steroids fail or become too toxic the most common drug is Cytoxan (cyclophosphamide) that comes in an oral or IV form more nove, agents such as rituximabstill have used that do not hav. ...Read more

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Can chemotherapy be used to treat polymyositis successfully?

Can chemotherapy be used to treat polymyositis successfully?

YES: Polymyositis is an inflammatory muscle disease that is typically treated initially with chemotherapy (usually with IV Cytoxan or cyclophosphamide). Once the disease is in remission, oral therapies are typically used in place of the IV chemotherapy. Steroids are also commonly used. ...Read more

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What should I know about dermatomyositis? What advice can you give for someone who has it?

Inflammation of musc: Inflammation of muscles. Assure that it is not caused by medications or by cancer. Further, assure exercises to maintain muscle strength. ...Read more

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Can colustrum tablets help my RA and polymyositis?

Can colustrum tablets help my RA and polymyositis?

It coud help but: Colostrum is a form of milk produced by the mammary glands of mammals (including humans) in late pregnancy. Most species will generate colostrum just prior to giving birth. Colostrum contains antibodies to protect the newborn against disease, as well as being lower in fat[3] and higher in protein than ordinary milk. ...Read more

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What are the pros and cons of traditional and naturopathic treatments for polymyositis?

Big difference: Polymyositis is a hyperallergic inflammation of the muscles with rapid wasting and debility. It responds well to systemic steroids and some other support pharmaceuticals. Naturopathy has nothing to offer for this condition. You need to see a rheumatologist as soon as possible to prevent serious complications. ...Read more

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How to find the best Rheumatologist with experience in treating Dermatomyositis in my area?

How to find the best Rheumatologist with experience in treating Dermatomyositis in my area?

Rheumatologist: Would start with finding out all the rheumatologists in my area. Then, can go to their practice website to see if they treat the specific medical condition.
Dermatomyositis is typically in the conditions treated by most rheumatologists.

Here is a link to help you find a rheumatologist jn your area.
https://www.rheumatology.org/Directories/Find-a-Rheumatologist ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


Dr. Ramachandran Srinivasan
236 Doctors shared insights

Dermatomyositis (Definition)

A very broad term generally encompassing otherwise uncharacterized general malaise, soreness, and fatigue. A variety of causes has been implicated over the years: viral, autoimmune, ...Read more