Doctor insights on:
Polymyositis And Dermatomyositis Antibody Panel
RA factor,ANA positive with polyarthritis ACCP negative and polyclonal hypergammaglobulinaemia. whats the diagnosis?
Auto immune disorder: The information you provided is not sufficient to provide a specific diagnosis. It suggest an auto-immune inflammatory disorder. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. ...Read more
Polymyositis is inflammation of the muscles. It is considered an autoimmune disease and which ones on inflammatory cells targeted their activity against muscle cells. This may be associated with fatigue and muscle weakness. There are several treatment options routinely use by a rheumatologists. I'm happy to do ...Read more
Ana direct positive ANA , ifa neg , rnp 2.3, CRP 5.4 ss-b2.7.Diag with lupus connective tissue and sjorgen all at once? Why 2 ANA tests different answ
They can change!: Appears you have mctd with sjogren's like features based on the labs and titers. No lupus marker present! ...Read more
Is positive anticardiolipin and positive antidsdna needed for lupus diagnosis? I have positive Ana, WBC 4.20 skin rashes, plus arthritis in joints
What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?
Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more
ANA 1:320 Homogenous pattern, positive ssDNA, and chromatin antibodies 60 u/ml. Fatigue and joint pain. Is lupus a possibility?
Yes: 1:320 along with positive ssDNA Ab and the symptoms you are having makes Systemic Lupus a strong possibility. I suggest seeing a Rheumatologist so they can also evaluate and potentially initiate treatments. ...Read more
Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?
Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read moreSee 1 more doctor answer
Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read moreSee 1 more doctor answer
Connective Tissue Dx: With a positive ana, you must now characterize it. The positive anticardiolipin abs need to quatified for the 3 types: igg, igm, and iga. The ones that are likely to cause thrombotic issues are in order: igm, igg, and iga. You need a rheumatologic or immunologic evaluation. ...Read more
Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.
Maybe: ANA positive diseases are related. Diagnosis is based not just on serologic testing, but also on your clinical symptoms. You should be evaluated by a rheumatologist in order to receive an accurate diagnosis and then receive the most appropriate treatment. ...Read moreSee 1 more doctor answer
Probability for lupus w/ seizures, peeling rash on hands, arthritis, low WBC and rbc, kidney/liver symt, and anticardiolipin antibodies and fam. Hist?
Ongoing polymyositis treatment @5mg prednisone&500mg sulfasalazine/day&17.5mg methotrexate/wk...What are appropriate jo1, wbc, abs mono, etc results?
Speak to your MD: With all due respect, your best place for this source of information is the physician providing your care, who knows you as a patient, your medical condition, and any other factors that may influence your treatment and results. This type of forum is best suited for general information on a topic, but not advice on specific care of a complicated problem. ...Read moreSee 1 more doctor answer
Ana positive low c3c and 4 no symptoms of auto immune could my fatry liver ve auto immune hepatitis?
Need more info: Your history, symptoms, physical exam and laboratory data are all essential in arriving at a diagnosis, which cannot be done on the internet. Hepatitis is usually manifested in the laboratory by the presence of elevated enzymes which are released from liver tissue. It is possible this represents autoimmune hepatopathy, but need far more data. ...Read more
PM/Scl: The paradox of rheumatologic diseases is that there are more lab tests in this area than any other, and they of relatively less value compared to the history and physical findings than in other fields. If your rheumatologist is comfortable with the diagnosis of "scleromyositis", which usually features anti-pm/scl, i'd accept it even with a single negative result, and proceed. ...Read more
Seizures mouth ulcers hepatocellular disease low blood count anticardiolipin antibodies 1:80 speckled ANA osteoarthritis spine Si joints LUPUS maybe?
Can mixed connective tissue disease be diagnosed with a positive ANA and positive rnp anitibodies?
Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?
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