Doctor insights on:
Polymyalgia Rheumatica Anti Inflammatory Hair Loss
Hair loss, otherwise known as alopecia, can be caused by different reasons, including damage to the hair shaft or follicles or fungal infections. There are two main types of alopecia. Alopecia areata occurs when the body's immune system attacks hair follicles and causes hair to fall out. Androgenetic (or androgenic) alopecia, on the other hand, is an inherited form of hair loss. With alopecia areata, hair can fall out in patches all over the body. With androgenetic alopecia, hair on the head first thins and then falls out. In men, this is called male pattern hair loss; in women, it is called ...Read more
I have joint pain and sometimes feel fever,twitching. Ana 1:40 but Rf, anti ccp , anti dna, anti sm,crp, Esr, scl-70 are negative, autoimmune disease?
Consultation advised: Unfortunately, Medicine is much too complicated to be able to give helpful advice on the basis of such limited information. An IN BOX Text consultation at Health Tap may be helpful.You would need to upload results of any tests, if available, as well as your medical history. You would NEED TO MAKE YOURSELF AVAILABLE for 24 hours to reply to any questions from your consultant.http://bit.ly/1OiIRcI ...Read more
Can systemic inflammatory response syndrome in a 5 year old with juvenile rheumatoid arthritis cause macrophage activation syndrome?
SIRS + JRA = MAS?: There is controversy as to whether macrophage activating syndrome is a real entity, versus it being confused for hemophagocytic lymphohistiocytosis (hlh). Hlh has much more defined criteria and can make a patient very sick (and requires chemo for treatment). A question i would have is could a patient with jra who develops sirs really have hlh. I would consult peds hem/onc (rheum mds may disagree). ...Read moreSee 3 more doctor answers
I have widespread joint pain, swelling. C-reactive protein <0.5 mg/dl, rheumatoid arthritis factor<8.6 iu/ml, sed rate 15mm/hr. Rheumatoid arthritis?
Polyarthralgia: You should be seen in person by a rheumatologist. Good luck. ...Read more
ANA 1:160 homogenous, anti ssDNA 42, normal Rh factor, ESR, anti dsDNA , neg HLA B27. Tests due to severe joint pain- is this indicative of lupus??
Not commonly: Unlike many meds used to treat autoimmune diseases (immune modulators that suppress the immune system) Plaquenil (hydroxychloroquine) has an antiinflammatory effect on autoimmune dss. So the risk of infections (seen with immune suppression) is uncommon. Major concern with this drug is effect on vision. Regular eye exams are recommended. ...Read more
My ana titer is 1:40 speckled pattern, indeterminate dsdna. I have flare ups of joint pain, stiffness, knees swell, Raynauds, fever, hair loss. Lupus?
Ongoing polymyositis treatment @5mg prednisone&500mg sulfasalazine/day&17.5mg methotrexate/wk...What are appropriate jo1, wbc, abs mono, etc results?
Speak to your MD: With all due respect, your best place for this source of information is the physician providing your care, who knows you as a patient, your medical condition, and any other factors that may influence your treatment and results. This type of forum is best suited for general information on a topic, but not advice on specific care of a complicated problem. ...Read moreSee 1 more doctor answer
Why not?: Are NSAID's helpful in fibromyalgia? Dr. Shah of NIH has shown tender points to be anoxic, ischemic, replete w. reactive substances; ala inflammation. FM sufferers have elevated substance P in spinal fluid. FM pain loci match tendon insertions & hurt upon mechanical pressure. Tendonitis? Concept of FM as a cognitive disorder is theoretical; as is idea that is not, in part, a peripheral neuropathy. ...Read moreSee 1 more doctor answer
Ana 1:640 only +lab. Dx: undifferconnective tissue disease(sx: immense fatigue, jt pain, sicca, photosensitivity). Can vague diagnosis cause such havoc on life?
Yes: Symptons can be very disruptive. An elevated ANA by itself does not a diagnosis of autoimmune disease make, but in conjunction with your symptoms, especially if they are persistent, the findings are very suspicious for this. Some individuals without autoimmune disease have elevated ANA levels. Some medications can cause this. Further evaluation is necessary, including a complete lab workup. ...Read moreSee 1 more doctor answer
Ana + 1:160 speckled anti native dsdna + 25.70iu/ml symptoms: hair thinning - do I have sle? Is hair thinning reversible w/ sle? Help very distressed
Possibly SLE: The dsdna antibody is very specific for sle, but is not perfect. Thinning of hair can happen in lupus but it can happen for many reasons. Most patients with sle also have low blood counts, a rash that is worse in the sun and leaves scars, joint inflammation or pain, sores in their mouth or possibly chest pain . Your test results are worrisome. If you have not seen a rheumatologist you should. ...Read more
Hum: In rheumatoid arthritis you might have for other reason inflammation , but muscle contraction is really not a feature of rheumatoid arthritis , flexure contracture might occurs , that are reducciton on the lengh of the tendons with dys functionallity those have to be evaluated and specific therapy instituted. Some patients with rheumatoid arthritis suffer of fybromyalgia, and have contractures. ...Read more
Ana positive, 1:320 centromere pattern. Some joint pain, some swelling, fatigue. Could I have lupus or scleroderma?
See below: Lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. The information you provided suggests scleroderma/crest. See this site for more info and discuss with your doctor. http://www.mayoclinic.com/health/scleroderma/ds00362. ...Read more
+ ANA 1280 homogenous/speckled, negative ena. Thinning hair, sun rash, joint pain, fatigue, paresthesias. Have blau syndrome/eos-can this cause ^ana?
See details: As you well know, this is an extremely rare condition. I could find no specific mention of its association with a positive ANA but i suspect any chronic inflammatory disease, especially one with an inflammatory arthritis can have the ability to generate a positive ana. The best advice is to discuss this with your rheumatologist if you are seeing one. ...Read more
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