Doctor insights on:
Polyhydramnios Birth Defects
Abnormal tissue Form: In simplistic terms a bd might be considered any abnormality found in a baby at birth. A better, more specific idea is a failure of a tissue or structure to form properly in fetal development. (cleft palate). A "disruption" can create a bd -loss of fingers to amnionic bands. Chromasome defects lead to several bd's like heart defects.
Alcohol: The avoidable agent best known for producing a variety of birth defects is alcohol.The spectrum of defects varies considerably with the amount consumed during pregnancy.The most involved are born to alcoholic mothers while as few as 2 drinks a day has a a significant risk. Defects vary from decreased intellect, heart, skeletal, facial and numerous other features., .
Environment: Although some birth defects are inherited others come from harmful environmental factors, and others are a result from complex interaction of genes and environmental factors. In about 50% of the cases the causes are unknown. Some birth defects can be prevented by not drinking or smoking or using street drugs during pregnancy. Talk to a healthcare provider about medications you are taking as well
3 to 4 %: The comprehensive NIH study of 50, 000 pregnancies with infants followed up to the age of 7 years revealed approximately 3 to 4 % major birth defects in the neonatal period (not including genetic disorders like cystic fibrosis), defined as a condition requiring surgery, causing a significant cosmetic problem, or a significant functional problem. By age 7 years, the percentage of affected was 7%See 1 more doctor answer
Varies: That varies tremendously. Some are minor and don't need fixing. Some are very severe and can't be fixed at all. Many are in between; they might not be completely fixable, but the right doctor might be able to make the problem considerably better.
Controversial: But the overall tide of opinion is that the answer is "no." there was laboratory evidence that lsd could cause damage to germ cells - sperm and eggs - even long after it's ingestion. However, studies of this have not yielded consistent results. There are no human studies, and the vast majority of lsd users (esp in pregnancy) use other substances as well. Avoiding any drugs in pregnancy is best.
Genes, environ, luck: A mix of genetics, exposure & chance. The formation of the heart is a very complex process as a simple vascular tube transforms into a specialized pump intertwining 2 separate circulations. Sometimes cells fail to migrate or grow-->may lead to septal defects. Structures may not form, and if they interfere with bloodflow (e.g., valve not opening), then downstream structures don't grow or develop.See 1 more doctor answer
Expert ultrasound: An ultrasound examination might show some abnormalities, but many might not be visible at 3 months. Also not all birth defects (congenital anomalies) are associated with chromosome abnormalities so screening the blood of the pregnant woman or testing the placental tissue would not detect them. Testing of the fetal blood or amniotic fluid isn't typically done early may be referred to experienced mfm.See 3 more doctor answers
Several: There are several types of heart defects, but doctors usually classify them into several broad categories. Cyanotic defects cause your baby to turn cyanotic, or blue. Obstructive defects block the normal flow of blood through the heart and its associated blood vessels. Septal defects cause "holes" between the heart's chambers. And hypoplastic defects make one side of the heart smaller.See 1 more doctor answer
Data presented on: This site http://www. Ncbi. Nlm. Nih. Gov/m/pubmed/15023170/ suggest an? Ed risk of congenital abnormalities. Since affected progeny had the same disorders as their fathers, a causal association with an immunosuppressant could not be proven. Please consult your wife's ob-gyn & request a pre-pregnancy visit with a prenatal genetic counselor to assist you in decision-making.