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Doctor insights on: Polyethylene Glycol 3350 Side Effects

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What's safer with less side effects suprep or golytely (polyethylene glycol) in my opinion golytely (polyethylene glycol) is but requires a lot more of liquids vs suprep with worse side effects?

What's safer with less side effects suprep or golytely (polyethylene glycol) in my opinion golytely (polyethylene glycol) is but requires a lot more of liquids vs suprep with worse side effects?

Equal: If taken properly they are equally safe. Suprep is easier to take because the volume is less. Given the large volume required for Golytely (polyethylene glycol) I rarely recommend it, except in hospitalized patients since it is more available. Both should be taken in split doses, both the evening before and about 4 hrs before the procedure for best results. ...Read more

Dr. Patricia Raymond
141 Doctors shared insights

Polyethylene Glycol (Definition)

Peg is the basis of a number of laxatives (i.e. Polyethylene glycol 3350, or miralax). Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. The preparation is sold under the brand names golytely, gavilyte c, nulytely, glycolax, fortrans, trilyte, among others. Read more ...Read more


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Does MiraLax (polyethylene glycol) count as a laxative? If someone took MiraLax (polyethylene glycol) everyday, what would the side effects be? Could this cause permanent damage?

Does MiraLax (polyethylene glycol) count as a laxative? If someone took MiraLax (polyethylene glycol) everyday, what would the side effects be? Could this cause permanent damage?

What's the concern?: Miralax (polyethylene glycol) is a generally safe, non-systemic lavage agent, intended to assist with laxation. Your voiced concern makes me question: for what symptoms has it been prescribed to you, what is the intended dose & duration of use, what have you tried before, what tests have been run prior to starting the product, what other symptoms do you have (weight loss, bleeding, pain), what's the underlying disease? ...Read more

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Is miralax (polyethylene glycol) safe 4 everyday use? Side effects? Linzess or miralax (polyethylene glycol) better for hard stool with straining? Able to go daily but very little with pebbles

Is miralax (polyethylene glycol) safe 4 everyday use? Side effects? Linzess or miralax (polyethylene glycol) better for hard stool with straining? Able to go daily but very little with pebbles

NO LAXATIVE: Should be used daily!
Hard Stool can be safely treated with COLACE (docusate sodium) (which is iteself NOT a laxative)
You should discuss IBS C (Irritable Bowel Syndrome-Constipation) with your PCP (Primary Care Provider)!!
Hope this helps!
Dr Z ...Read more

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Miralax (polyethylene glycol) side affects?

Miralax (polyethylene glycol) side affects?

Abdominal problems: Miralax (polyethylene glycol) dosed at 17 gm/day (a heaping tablespoon in 4-8 ounces of fluid) max 34gm/day. Some side effects are abdominal pain/bloating, diarrhea, cramping, gas, rash. High doses particularly in elderly can cause excessive diarrhea/ stool frequency which may result in dehydration. Stop use if fecal urgency/incontinence occurs. Do not use for more than 2 weeks except directed by physician. ...Read more

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18 yr old son hasn't had a bm in 3 days I gave him miralax (polyethylene glycol) for 2 days and still nothing should I give him something else? He has left side discomfort.

18 yr old son hasn't had a bm in 3 days I gave him miralax (polyethylene glycol) for 2 days and still nothing should I give him something else? He has left side discomfort.

Med takes longer: Miralax (polyethylene glycol) is a wetting agent not a laxative. Relief from the discomfort of constipation is best done with a washout of the rectal vault & sigmoid colon using an enema or stimulant suppository like ducolax. Miralax (polyethylene glycol) will take about 3 days to work its way through the system if the kid is having bowel movements. It's longer term use over weeks to months may help fix the issue. ...Read more

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Sons on miralax, (polyethylene glycol)2 cap fills a day since he 2 yo, now he's 7. Recently Ex-Lax has been added every other day for constipation. Long term side affects?

Sons on miralax, (polyethylene glycol)2 cap fills a day since he 2 yo, now he's 7. Recently Ex-Lax has been added every other day for constipation. Long term side affects?

Constipation: Long term use of Miralax (polyethylene glycol) is not associated with any long term side effects. The same can not be said for ex lax. I do not want to counter the advice given by his doctor as I do not know his medical history and how severe his constipation is. The problem with laxatives when they are used long term is the body gets used to them and then we can't go without them, but if he isn't anyway no problem. ...Read more

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No appetite, sharp pain in left side of chest when I bent over to pick something up, no bowel movement for days even after taking miralax, (polyethylene glycol) sound serious?

No appetite, sharp pain in left side of chest when I bent over to pick something up, no bowel movement for days even after taking miralax, (polyethylene glycol) sound serious?

GI Issues: It sounds like you've got some GI issues that need close physical examination. Stop taking the MiraLAX (polyethylene glycol) and see your pcp asap to be sure what it is. Gerd, upper GI ulcers, gastritis etc. Could be responsible for the symptoms. You'll get a clearer picture with a physical exam by your doctor. Good luck! ...Read more

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What are the long term effects of taking miralax (polyethylene glycol)?

What are the long term effects of taking miralax (polyethylene glycol)?

Not much: Miralax (polyethylene glycol) is generally felt to be ok for long term use. There are other laxatives, called stimulant laxatives that can cause problems. Miralax (polyethylene glycol) seems to work safely as it is not absorbed by the gut. It draws water in, thereby keeping stools soft without affecting other systems or adversely affecting the intestine as it "passes through" the GI tract. ...Read more

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Can long term MiraLax (polyethylene glycol) become toxic due to buildup in the body?? Neurological/cardiovascular effects?? I have Gilbert's disease..

Can long term MiraLax (polyethylene glycol) become toxic due to buildup in the body?? Neurological/cardiovascular effects?? I have Gilbert's disease..

No: miralax (polyethylene glycol) stays in the Gastrointestinal tract and doesn't get absorbed into the body, so their should be no neurologic affects. Even if you have Gilbert's disease, which affects the liver, the miralax (polyethylene glycol) doesn't go to the liver at all. It just draws water into the intestinal tract ...Read more

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What happen if I take "polyethylene glycol 3350". For a month?

What happen if I take "polyethylene glycol 3350". For a month?

Many use it longer: You should find out why you have chronic constipation first such as ruling out thyroid disease etc. If no underlying disease, try the natural way such as fibers, roughage, and adequate fluid daily. This med is relatively safe to use and many patients use it for months to yrs. Like any other med, use smallest effective dose for shortest possible time. Consult doc. Good luck. ...Read more

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Does polyethylene glycol 3350 nf powder cause problems?

Does polyethylene glycol 3350 nf powder cause problems?

Constipation Relief: Polyethylene glycol is a non-absorbed sugar substance that pulls water into stool, causing soft stools or diarrhea. This medication is used to relieve constipation. It is not dangerous, but will cause watery diarrhea if used in excess. ...Read more

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Is it safe to take polyethylene glycol 3350 powder daily?

Generally yes: Also known as "MiraLax", this is generally safe to take daily, however it should be done under the direction of a physician if there is an ongoing problem which requires a daily medication for constipation. Also, as with any other over the counter medications, adhere to the directions on the bottle regarding daily dose. ...Read more

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How much polyethylene glycol 3350 nf should I take to prepare for my colonoscopy?

How much polyethylene glycol 3350 nf should I take to prepare for my colonoscopy?

Colonoscopy prep: There are different types of preps some with pills and other with liquids
check with your doctors office as to his preference and instructions for you specifically. ...Read more

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Urgent is it safe for my 4 year old to take smooth lax polyethylene glycol 3350 power. He weighs 36 pounds. If so how much. It says to take 17g?

Safe: The popular brand name for this medication is called miralax (polyethylene glycol). It is used for constipation. You can give half to one capful dissolved in water every day. One cap is usually 17g. The dosage is usually titrated based on the response. The goal is to have one soft bowel motion every day. ...Read more

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How often should I take polyethylene glycol 3350 to soften stool?

Careful: Polyethylene glycol is a stimulant laxative, not a stool softener. Stool softeners that contain docusate are safe to take up to 4 times per day whenever you need it. Peg products can cause problems if used more than once or twice per day, or if used regularly for an extended period of time. Also, drink plenty of water while using laxatives, both to help move things along and prevent dehydration. ...Read more

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What is miralax (polyethylene glycol) used for?

Relieve constipation: It is a laxative, use to relieve constipation. It can be found over the counter. ...Read more

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Can I up my dosage of miralax (polyethylene glycol)?

Can I up my dosage of miralax (polyethylene glycol)?

Is dose-dependent...: The more MiraLAX (polyethylene glycol) you take the faster it works. As a once over-the-counter dosed laxative you may not see results for 3-4 days, but as a multi-dosed colonoscopy preparation (when used under doctor's advice) expect laxation within hours. As with any laxative however understand its mechanism of action, its risks, & treatment goals & make sure you are not missing obstruction, dysmotility, inflammation ...Read more

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Are colyte (polyethylene glycol) and suprep the same?

They are different: These are both used for bowel prep preceding colonoscopy or bowel surgery but they contain different ingredients. ...Read more

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How long can I take miralax (polyethylene glycol) for?

Miralax (polyethylene glycol): You can take miralax (polyethylene glycol) indefinitely as long as you need it. Best wishes. ...Read more

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Can you explain how miralax (polyethylene glycol) works?

Can you explain how miralax (polyethylene glycol) works?

Osmotic laxative: If you remember from science class putting sugar or other dry compound in small amount of water and placing it in lager container of tap water the tap water would cross the plastic bag and dilute the sugar water......Miralax (polyethylene glycol) is an osmotic laxative it prevents water from being absorbed in the gastrointestinal tract thereby getting more water to the anus vice a dry poop. ...Read more

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What is the best way to take miralax (polyethylene glycol)?

Miralax (polyethylene glycol): Miralax (polyethylene glycol) can be (dissolved) mixed in any liquid. 4 to 8 ounces of liquid is recommended. ...Read more

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Can you just put miralax (polyethylene glycol) on pancakes?

Miralax (polyethylene glycol): It is recommended that Miralax (polyethylene glycol) be mixed in 4 to 8 ounces of fluid. ...Read more

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Is it ok to take miralax (polyethylene glycol) for 3 months?

Is it ok to take miralax (polyethylene glycol) for 3 months?

Depends on reason: No universal answer to this. Chronic constipation can have many causes such as side effect of meds, metabolic disease (eg. Diabetes, hypothyroidism), neurologic disease, low fiber diet, obstruction from colon polyps/colon cancer. This is why over-the-counter laxatives should not be used long-term for symptoms of unknown reason; getting to the root of the problem is highly advisable. ...Read more

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Is it okay to use 2 scoops of miralax (polyethylene glycol)?

Is it okay to use 2 scoops of miralax (polyethylene glycol)?

Yes: It is recommended that you use 3 heaping tablespoons of MiraLAX (polyethylene glycol) in every 8 oz of liquid. That is about 17grams daily. ...Read more

Dr. Eric Weisman
47 Doctors shared insights

Golytely (Definition)

GoLytely is a laxative which is a ...Read more


Dr. Sheila Smith
46 Doctors shared insights

Colyte (Definition)

CoLyte is a laxative which is a ...Read more