Doctor insights on:
Polycythemia Vera Treatment Diet
refers to all the physical matter humans (like all living creatures) must take in on a recurring basis; only partially for energy. Like all life on planet humans are open systems which keep tearing down their structure & require intake of atoms/molecules from which to rebuild their structure. Intestinal lining cells replaced ~every 3 days. CaPO4 in bones ~every 6 years, ...Read more
I am being tested for polycythemia vera. Doc thinks I have it. If I do have it and since I didn't start treatment yet, can I still get a nose job?
Not often: Polycythemia vera is caussed by multiple factors. Typicall the treatment is theraputic phlebotomy but if you had any condition that would be negatively affected by the plebotomy or physician preference you might have this done. Consider the cuase of the condition also would affect the treatment. ...Read more
Polycythemia vera is the overproduction of red blood cells by the bone marrow. Complications result from formation of blood clots due to the increased thickness of the blood. Therefore, this is where treatment of the disorder is aimed.
Blood can be drawn at intervals (phlebotomy) to decrease its thickness, and some patients are given Aspirin to reduce the risk of blood clots. ...Read more
My mom got a blood disease called polycythemia vera. May I know the price for interferon-alpha which can be used to cure this disease. Also, could you recommend me some brand of this medicine?
She needs a speciali: A good specialist is what she needs first. You should seek the advice of a hematologist who works in a major cancer center. P. Vera has some new treatments(jak2 inhibitors) which are in clinical trials. Interferon(has some activity and can be beneficial but it is an older treatment which has many serious side effects and it is very expensive. Too alpha-2b) also called introna) ask for this bran. ...Read more
Being treated for polycythemia vera with phlebotomies. How does taking blood approximately every six weeks treat this condition? I don't understand.
Decr risk clotting: Keeping the hematocrit in a normal range (hct <45% in men & 42% in women) can decrease the risk of thrombosis (blood clots) in polycythemia vera (pv). Phlebotomies can reduce the hct. For patients at high risk for thrombosis (age >60 or hisotry of thrombosis) phlebotomy can be combined with Hydroxyurea to lower hct. Keeping WBC in the normal range may also be important. ...Read more
My mom has polycythemia vera. What precautions, can I take to ensure that I won't get the same in a few years, when I reach the age she was when...?
Annual physical : P vera is not considered an inherited disease-meaning that there are no genes that cause the disease that are passed on from parent to child. It is probably related to aging, and it is not necessarily a terminal diagnosis, but some cases are more severe and require more treatment than others. Annual physicals that include complete blood counts will usually pick up an increase in red cells. ...Read more
Polycythemia vera: Phlebotomy (blood removal) will be needed to maintain your blood at certain level to prevent stroke or blood clot. In addition, Aspirin is recommended if there is no risk of bleeding or other contraindication. For patients with high risk to develop stroke/clot (age>60 or prior history of clot)- medication called-hydroxy-urea- is also recommended. Discuss with your hematologist. ...Read more
Maybe blood draw: Depends on how high the blood count and whether symptoms are present. Also, if pcv is caused by something (secondary polycythemia), that cause needs to be addressed. Smoking, sleep apnea, hemochromatosis are common causes of secondary pcv. If primary and symptoms exist the main treatment is phlebotomy — drawing blood off regularly to decrease the hemoglobin. ...Read more
PCRV is a : Myeloproliferative disease associated with too many red blood cells. Polycythemia -- too many cells -- ruba -- red -- vera -- true. ...Read more
Iron rich: Iron rich foods may help if avoided but is symptomatic treatment is advisable. ...Read more
Polycythemia: Polycythemia rubra vera and polycythemia vera are the same thing — a myeloproliferative disorder which causes production of too many red cells (and usually white cells and platelets also). Polycythemia or erythrocytosis just means someone has too many red cells, whether due to prv, high altitude, sleep apnea, emphysema, certain cancers, or certain congenital abnormalities of red cell production. ...Read more
To follow up on previous question, i just don't understand how I could have polycythemia vera with my age/sex. What exactly is polycythemia vera?
Polycythemia: Ruba vera or too many cells of the red blood in latin is an acquired, not genetic, disease in the myeloproliferative category. That means the body regulation of blood cell production is off, and in your case you make too many rbcs. Rare at 29 but not impossible. Stay on the plan with your hematologist -- easily and successfully treated. ...Read more
Not that I know of.: The big changes of this are elevated rbc count, hemoglobin, hematocrit, and decreased ESR (erythrocyte sedimentation rate). The elevations come without decrease in volume, and can be up to 70-80% for hematocrit, and 8-9 million rbc count. Changes in RDW may be from so many rbc's in the system, but even if they do occur, do not apparently have effect on prognosis or relevance to the cause of this. ...Read more
As below: Polycythemia vera is a type of cancer of the bone marrow where your blood cells (white/red cells, platelets are produced). It is one of the chronic myeloproliferative neoplasms where there is a clonal proliferation of myeloid cells. In PV there is an elevated red blood cell mass (RCM). This can cause high Hct >= 32 in W. Also Platelet count & White blood cell count could be elevated too. ...Read more
Definitions: Polycythemia vera is a clonal proliferation of mutated cells. This makes it a tumor. There are by definition no benign tumors of the blood-forming as it is the nature of these cells to spread throughout the body and to go other tissues. Unlike solid cancers, "p vera" will not destroy organs by direct invasion. It is unlikely to kill until it acquires additional mutations and transforms. ...Read more
Easy to check: Polycythemia vera is a myeloproliferative disorder and is unlikely to be hereditary in nature. However, it is easy to check by looking at a CBC (complete blood count). If the rbc mass, hemoglobin and hematocrit are elevated then further w/u can be instituted; if they are normal then occasional monitoring can be done. ...Read more
Blood cancer: P vera is a form of blood cancer and affects the bone marrow. Any disease affecting the bone marrow may interfere with the normal production of white cells and make the person prone to infections. Consult this site for more info: http://www.mayoclinic.org/diseases-conditions/polycythemia-vera/home/ovc-20307463 ...Read more
Depends.: Prv patients are advised to take Aspirin for clot prevention. Anticoagulants like warfarin or xarelto have specific indications such as treatment for a blood clot or stroke prophylaxis in heart disease. I would not use it outside those indications because of greater bleeding risk vs aspirin. No published data on xarelto in prv but should be ok for proper indications. ...Read more
PV&life expectancy: Life expectancy of patients with polycythemia vera (especially if younger than 50 years) was reduced compared with the general population. It is very important to follow up with your hematologist and keep your hematocrit to less than 45% to reduce risk for thrombosis/clotting. Best of luck. ...Read more
No: My understanding is that Jakafi (ruxolitinib) would not have benefit in JAK-negative PV. Overactive JAK pathway signaling is a key driver to the excess cell production seen in polycythemia vera. Jakafi (ruxolitinib) blocks or inhibits this pathway. Apparently there are a few people, such as yourself, for whom this JAK pathway is not the principle mechanism. Other treatments need pursuing. Good wishes:) ...Read more
Polycythemia vera: Your bone marrow is over-producing red blood cells. Because of that your blood can get very viscous (gooey?) and can clog up in small vessels, say in the brain or lungs and thus cause small infarcts or strokes. So every once in a while you will have to be bled to reduce the number of red blood cells in your blood stream. It is the opposite of anemia(too few RBCs). ...Read more
What does this mean? "Severe crythroid hyperplasia consistent with hematological diagnosis of polycythemia vera"
Erythroid hyperplasi: Erythroid hyperplasia is an excess of red blood cell precursors in the bone marrow. This is can be due to benign/reactive or neoplastic processes. Polycythemia vera is a primary bone marrow disease in which too many red cells (erythroid cells) are produced due to mutation in a cell line. Diagnosis is made on blood findings. This is chronic disease (not same as acute leukemia) but needs treatment ...Read more
Is it true that having polycythemia vera and exercising can cause muscles to grow quicker than the average person?
What happens if polycythemia vera is diagnosed late, does that mean one is at a greater chance of developing cancer?
Please explain what does severe crythroid hyperplasia consistent with hematological diagnosis of polycythemia vera mean?
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