Doctor insights on:
Polycythemia Cause Bleeding
Abnormal platelets: Individuals with polycythemia (an acquired disorder of the bone marrow that causes an abnormal increase in all three blood cell types: red blood cells, white blood cells, and platelets) have an increased tendency to form blood clots that can result in strokes or heart attacks. Some people also have abnormal bleeding because their platelets (responsible for clotting) are abnormal. ...Read more
Is it possible to have polycythemia vera with normal pt, ptt, & INR plus normal bleeding time? High rbc, hgb, & hct.
Yes: Pt, ptt, inr and bleeding time have no role in the diagnosis of p. Vera. If you're eighteen years old, i'd look hard for a different cause if you are actually significantly polycythemic. There are plenty of really fit young men whose hemoglobin is a bit higher than the reference range -- athleticism to odd hemoglobin genes to something in your "gym health drink" you don't know about. Good luck. ...Read more
GI bleeding 1+yr; never anemic. Latest RBC 4.6 platelets 350. Could I have polycythemia masked by chronic bleeding? Itching spells esp. after showers?
Possible but rare: Polycythemia, which mostly is an increase in red blood cells but can affect other blood cell lines as well, has multiple complications, mostly physical. There are rare reports almost always in adults of acute onset of psychiatric disorders such as psychosis or depression. This could be secondary to strokes, which can occur because the blood is "too thick.". ...Read moreSee 1 more doctor answer
Have JAK2-negative polycythemia. Any further testing that might diagnose the cause? Do not smoke (quit 5 years ago) and do not live in high altitudes.
Not that I know of.: The big changes of this are elevated rbc count, hemoglobin, hematocrit, and decreased ESR (erythrocyte sedimentation rate). The elevations come without decrease in volume, and can be up to 70-80% for hematocrit, and 8-9 million rbc count. Changes in RDW may be from so many rbc's in the system, but even if they do occur, do not apparently have effect on prognosis or relevance to the cause of this. ...Read more
No: Pv by itself does'nt cause low grade fevers. However, pv can increase your risk to have blood clots and blood clots can give you low grade fevers also, pv can transform into other condition i.E myelofibrosis as well as mds/ acute leukemia in about 20%-30%). Low grade fevers occur quite commonly in myelofibrosis and acute leukemia. See your md to rule out other condition i.e. Autoimmune , infection. ...Read more
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