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Doctor insights on: Polyarteritis Nodosa Children

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Is polyarteritis nodosa an autoimmune disease?

Is polyarteritis nodosa an autoimmune disease?

Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more

Dr. Charles Lombard
162 doctors shared insights

Polyarteritis Nodosa (Definition)

A disease that causes arteries to ...Read more


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Is polyarteritis nodosa always an autoimmune disease?

Is polyarteritis nodosa always an autoimmune disease?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It is immune mediated and exact cause is not known. ...Read more

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How are polymyalgia rheumatica and giant cell arteritis diagnosed?

How are polymyalgia rheumatica and giant cell arteritis diagnosed?

Overlapping: They are overlapping disorders. They can occur separately or together. Clinical experience of the doctor and elevated erythrocyte sedimentationrate are the most reliable findings. ...Read more

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What causes polyarteritis nodosa?

What causes  polyarteritis nodosa?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It can affect infants. Dilated arteries and strictures resemble rosary beads. ...Read more

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Dr. K. Olson Dr. Olson
3 doctors agreed:
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Can polyarteritis nodosa lead to vasculitic neuropathy?

Dr. K. Olson Dr. Olson
3 doctors agreed:
Can polyarteritis nodosa lead to vasculitic neuropathy?

Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read more

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Is polymyalgia rheumatica considered an autoimmune disease?

PMR : Pmr is an inflammatory disorder that affects proximal muscles of shoulder joint and hip joint due to unknown causes. There is inflammation with elevated ESR and crp. There is mild anemia and effusion of tendons around shoulders on us. Temporal arteritis(ta) is seen in 15% of pmr patients. Pmr occurs in 50% of ta patients. It occurs in genetic predisposition triggered by environmental factors. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Which percentage of  diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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Is takayasu's arthritis curable?

Is takayasu's arthritis curable?

No: Takayasu's arteritis (it's not an arthritis) is a vasculitis, which is inflammation of the vessels. Etiology remains unclear, but the immune system is thought to contribute the most to disease. Immunosuppressive meds help control symptoms, but this disease tends to flare. The more severe and frequently the pt flares, the more worried i get about prognosis and may identify pts who need surgery. ...Read more

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What causes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA)?

What causes granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA)?

The exact causes of GPA — formerly known as Wegener's granulomatosis — and MPA are unknown: GPA and MPA are both types of inflammation of the blood vessels (vasculitis). It is believed that one or more genetic and environmental factors, such as infections, allergic reactions, certain drugs and diseases, might trigger an abnormal immune system response that causes GPA and MPA symptoms. However, no specific infection or event has been identified as the cause. GPA and MPA develop when the immune system mistakenly identifies blood vessel cells as foreign invaders and attacks them. The vessels become inflamed, causing them to narrow or close off, disrupting the flow of blood to various organs and causing organ and tissue damage. No matter the cause, early diagnosis and treatment of GPA and MPA are essential for a full recovery. ...Read more

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Is takayasu arteritis deadly?

Is takayasu arteritis deadly?

Unusual: Really unusual . This will depend on the artery that is involved with the disease , for example if renal arteries are involved the patient can developed severe high blood pressure and possible renal failure which can lead to death ...Read more

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What is wegener's granulomatosis vasculitis?

What is wegener's granulomatosis vasculitis?

See details: It is a form of vasculitis effecting medium sized arteries and associated with a positive canca blood test. It usually begins as chronic sinusitis but with time can effect many other organ systems including eyes, heart, kidneys, joints, lungs and the nervous system. There are very effective treatments available. ...Read more

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Takayasu arteritis--causes and cures?

Takayasu arteritis--causes and cures?

Steroids or surgery: Prednisone/ steroids are the main way of treatment . Some patients will require open bypass surgery in case of steroid resistance . Causes are idiopathic or unknown .. It is an autoimmune disease affecting the wall of large blood vessels causing narrowing by fibrosis. ...Read more

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What causes polyarteritis nodosa?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It can affect infants. Dilated arteries and strictures resemble rosary beads. ...Read more

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What are the tests for polyarteritis nodosa?

Polyarteritis nodosa: Diagnosis made by clinical suspicion based on patient symptoms and findings .Lab findings may include elevated wbc, ESR , CRP and in some patients positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients . Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied. ...Read more

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What are the symptoms of polyarteritis nodosa?

What are the symptoms of polyarteritis nodosa?

Ployarteritis nodosa: Symptoms depends on organ or system affected. Symptoms are fatigue , fever, muscle , joint pains, unexplained weight loss, anorexia . Based on organ involved kidney failure, hypertension due to kidney involvement, stroke , seizures due to brain involvement, abdominal pain due to bowel perforation , chest pain , heart attack due to heart involvement wrist drop, foot drop due nerve involvement. ...Read more

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I want to know my options for treating polyarteritis nodosa?

I want to know my options for treating polyarteritis nodosa?

Limited: Despite many trials, corticosteroids are still the cornerstone of treatment. Cyclophosphamide may be added in more severe cases or in resistant cases of polyarteritis that are not hepatitis b related. Newer agents to treat this condition exist and treatment should only be attempted by a physician intimately familiar with the condition. ...Read more

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What is the definition or description of: Polyarteritis nodosa?

Polyarteritis nodosa: Polyarteritis nodosa (panarteritis nodosa, periarteritis nodosa or Kussmaul disease) is a disease which causes swelling and inflammation to arteries. ...Read more

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What is inflammatory polyarteritis nodosa? How is it treated?

Inflammation - vesse: It is inflammation of blood vessels, Depending on which blood vessel are involved is where the symptoms and signs are. as the muscle is inflammed, the vessel narrows interferring with the blood flow. This is how polyarteritis causes its problems. The physician will evaluate the patient, get labs and perform imaging to help evaluate for therapy. ...Read more

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What new research is there regarding vasculitis and polyarteritis nodosa?

What new research is there regarding vasculitis and polyarteritis nodosa?

Treatment.: Polaryarteritis & temporal arteritis, are found to be quite treatable without high dose Prednisone and all it's side effects. The new drugs are tnf-a inhibitors and new research shows quick remission in most cases. ...Read more

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Is polyarteritis nodosa an autoimmune disease?

Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more

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Is polyarteritis nodosa always an autoimmune disease?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It is immune mediated and exact cause is not known. ...Read more

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Dr. K. Olson Dr. Olson
3 doctors agreed:
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Can polyarteritis nodosa lead to vasculitic neuropathy?

Dr. K. Olson Dr. Olson
3 doctors agreed:

Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read more

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I have been diagnosed with polyarteritis nodosa although both biopsy and blood test have come back negative. Is this diagnosis likely to be correct?

I have been diagnosed with polyarteritis nodosa although both biopsy and blood test have come back negative. Is this diagnosis likely to be correct?

Polyarteritis nodosa: Diagnosis made by symptoms and findings which may include elevated wbc, ESR , CRP and in some positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients . Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied . At times biopsy is targeted for affected tissues. ...Read more

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Dr. Timothy Wu Dr. Wu
1 doctor agreed:
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Diagnosed with polyarteritis and i'm unable to work and i'm walking with a stick. Will I have this for life?

Dr. Timothy Wu Dr. Wu
1 doctor agreed:

Polyarteritis Nodosa: "pan" is a type of vasculitis that causes inflammation of the blood vessels all over the body, affecting just about every organ imaginable. The inflammation can cause blockages of the arteries which leads to an interruption of blood flow and a variety of other issues depending on the organ affected. It is a chronic issue that is life-long, but it can be controlled with medication. Consult an md. ...Read more

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Is polyarteritis nodasa an emergency?

No: But it is important to make the diagnosis to avoid complications from it and to treat it appropriately. ...Read more

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Does a cure exist for polyarteritis?

Does a cure exist  for polyarteritis?

No: Polyarteritis nodosa is a type of vasculitis (blood vessel inflammation) that is often fatal if untreated. Fortunately, medicines exist that can control the symptoms and the disease can go into remission. However, that is not a cure. ...Read more

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How can I deal with work and schoo when dealing with polyarteritis?

How can I deal with work and schoo when dealing with polyarteritis?

No good answer: The is no good answer. Just realize that there may be times that disease activity may necessitate you resting and adjusting your work schedule so you do not become exhausted. The better the disease is controlled, the less it will affect your life. ...Read more

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What are treatments for polyarteritis nordosa?

What are treatments for polyarteritis nordosa?

Polyarteritis nodosa: In pan damage is due to impaired blood supply to vital tissues as a result of inflammation of medium to small arteries . Goal of treatment is to reduce inflammation with Prednisone , and Cytoxan as main drugs. Other medications include methotrexate, Leflunomide and Rituxan (rituximab) . Problems due to pan need to be treated such as HTN , renal failure, seizures, stroke, bowel perforation , neuropathy etc. ...Read more

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