Doctor insights on:
Polaramine Sedating Antihistamine
Benadryl (diphenhydramine).....: Is probably the most readily available sedating antihistamine. It is a common ingredient in over-the-counter (OTC) preparations for sleep, such as Tylenol (acetaminophen) PM -- the PM part is diphenhydramine, the generic name for Benadryl. Another one I like to use is hydroxyzine (also known as Vistaril or Atarax) but that is only available as a prescription, however its metabolite is Zyrtec, which is OTC. ...Read more
I understand that one cannot become addicted to antihistamines, however, can't people become addicted to the sedating effects of drugs?
Tolerance: You become tolerant to the sedative effect of first generation antihistamines and with time you will no longer feel sedated from them. If you are using then as a sleep aid, will you need more with time to achieve the same level of sedation. It is not an addiction, it is tolerance to the medication. ...Read more
If I take Benadryl (diphenhydramine) before getting on a plane, will the sedation from it help with my plane anxiety?
I am taking Benadryl (diphenhydramine) with minimal side effects only light sedation. Going to try hydroxyzine. Will I get more side effects than Benadryl (diphenhydramine)?
If I have developed resistance to benadryl's sedating effects (+/-150mg), will it still work4allergy?
Give it a try: Diphenhydramine (benedryl) is a very effective antihistamine, holding on to histamine binding sites better than some products. Its drawback other than sedation has been its limited duration of effect, eclipsed by products like zyrtec (cetirizine) that can last all day. Sedation is not a measure of its worth, only its ability to get into your brain and mess with neurotransmitters. ...Read more
10mgs a day amitriptyline for migraines. Is it ok to skip a day occas? Is missing a dose dangerous? What if I feel overly sedated from Benadryl (diphenhydramine) once?
My son is scheduled for dental work with sedation tomorrow & has to fast from tonight. Is it safe to give Benadryl (diphenhydramine) in the morning for motion sickness?
Taking lethal over: Dose would do that. Lethal overdoses of antihistamines are rare. Are you considering taking an overdose of antihistamines? If so, please get help right away. You can use national suicide hotlines 24/7 at 1-800-suicide (1-800-784-2433) or 1-800-273 – talk (1-800-273-8255). If you have accidentally taken too many antihistamines please contact 1-800-222-1222 (poison control hotline). Take care. ...Read more
Which one: First generation antihistamines are sedating, second generation ones are not, overdosing on the latter hardly kills, but may cause sedation. Overdosing on first generation antihistamines may be more of a problem, but again they are safe in high doses. ...Read more
Several are good: Loratedine (Alavert, Claritin), Cetirizine (Zyrtec)and Fexofenadine (Allegra)are all effective. Dyphenhydramine (Benadryl) is short acting so if you want the reaction not to come back in the middle of the night then one of the above would be better. Remember that you should not give children under 2 antihistamines without checking with your doctor. Between 2-4 y/o you should also ask. Not for colds ...Read more
Antihistamines: They are almost all over the counter. The only one that is not yet is one used for deep sedation called hyroxyzine. ...Read more
Yes: Taking antihistamines with betablockers like propranol is typically very safe. ...Read more
Typically no: Antihistamines are generally not considered a group of medications that directly cause gout. However, antihistamines can cause dryness, and if that progresses to dehydration, then gout attacks can occur with a higher frequency. This would be an indirect cause. Antihistamines generally don't cause significant dehydration. Aspirin can make gout worse, as can other salicylate-containing meds. ...Read more
Cross into brain: Older antihistamines, such as diphenhydramine, or chlorpheniramine, actually cross the barrier between the bloodstream and the brain. This causes many people to feel drowsy or sedated. It can make some people irritable, or even cause insomnia. For this reason, the "non-sedating" antihistamines were developed. These medications cause much less drowsiness, and are better tolerated. ...Read more
Depends: Most people respond best to zyrtec or xyzal, (levocetirizine) as long as they don't get drowsy with them. Everybody reacts differently to different antihistamines, though; most people with urticaria will try many of the available antihistamines, alone or in combination, under a physician's supervision, to get the best control of their hives. ...Read more