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Doctor insights on:
Pneumococcal Antibody Deficiency
1
Are immune globulin antibodies a injection?

Yes.: They may be given intravenously, intramuscularly, or subcutaneously depending on the dose and usage. ...Read more
Antibody (Definition)
An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more
2
HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Need any medication or vaccine?

Excellent question: and your story stumps many a doctor, often! :) a lot of the recommendations depend on - are you someone with risk factors for HBV? is this the first time that it has been checked? are your liver enzymes normal? are you about to undergo any procedures/ treatments that could put you at risk for HBV? If you have no sig risk factors, yes, I'd vaccinate you if there's potential for exposure. ...Read more
3
Interpret hepatitis B panel results:
Hep B surface antigen (HBsAg) - Non-reactive, Hep B core Total antibody Anti-HBc Reactive, NAT Non-reactive?

Past infection: You had infection with hepatitis B but do not have active infection now. ...Read more
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4
Is IVIG given for pneumococcal antibody deficiency. What cause pneumococcal deficiency? What's the usual treatment?

More Complicated: IVIG or subcutaneous forms are given for immune deficiencies. There is a type of immune deficiency called common variable immune deficiency which usually results in low IgG antibody and impaired response to pneumococcal vaccination of infection. If you are worried about this, you should see an immunologist for further evaluation. ...Read more
5
Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?

You had mono...: Your mono-like symptoms likely prompted the testing- i hope you are starting to feel a little better. Testing for different antibodies (igm and igg) against ebv, requires careful interpretation. In early phases of infection, the igm level peaks first followed by a decline; levels of igg peak afterwards, and may remain elevated for quite a while. ...Read more
6
Reactivated EBV 9 months after first infection. Could i be immunodeficient? Antibody count: 65 ab VCA igm; 53 ea ab igg; 431 ab VCA igg; 289 ebna igg.

No: Unfortunately ebv stays alive forever in one's lymphocytes and can get activated easily in susceptible people without known immunodeficiency. However you may call that an immunodeficiency given that all people have been infected with it yet only few would have recurrent ebv problem. ...Read more
7
Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?

Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more
8
Ebv panel. Ebv nuc antigen igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6. Please explain. Concerned about spleen. Symp=fatigue/fog?

? Active infection: It's impossible for me to answer with certainty since i don't know the normal ranges your lab uses. If early ag & vca igm are elevated above normal this indicates active ebv infection.I don't know if it is acute or chronic without knowing your history. If chronic i see that as a sign of poor immune function.Immune-boosting herbs/supplements & IV vit c drips may help, but find why immunity is poor. ...Read more
9
My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?

Treat the person: Lab tests mean nothing in isolation, and have many false positives and false negatives. The decision to make a trial of a gluten-free diet will be between you and your gastroenterologist or dermatologist based on the big picture. ...Read more
10
Could IgG subclass deficiencies be caused by plasma b cell diseases/disorders?

Yes: It is possible to have malfunction of immunoglobulins or low levels in b cell disorders. A subclass deficiency by itself is usually not clinically significant and does not warrant treatment but if an underlying b cell disorder exists, it should be remedied. ...Read more
11
Hi my measles IgG antibody -ve(57.35IU/L),mumps IgG antibody -ve(2.72 RU/ml),rubella IgG antibody -ve(<10 IU/ml)what should i do?can i get vaccinated?
By all means: This would be a great idea.
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12
Hiv 1/2 blood analysis:
-antibodies and p24 antigen (chemiluminescence): reactive-2, 741
- IgG antibodies (enzyme immunoassay):nonreactive
in this case, is HIV infection accurate?
HIV: A western blot is essential to confirm of refute HIV infection and it would also be in your best interest to see an infectious disease specialist asap whether you are positive or negative. ...Read more
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13
What does a high EBV viral nuclear capsid antibody, a high EBV viral capsid antibody IgG and a high IgM EBV viral capsid antibody mean?

Acute infection: A high igm antibody level usually means current or recent infection with ebv. ...Read more
14
What is immune globulin ig?
Protein, antibody: An immunoglobulin, also called an antibody, is a protein that binds susbtances to eliminate or neutralize them. Most of immunoglobulins are in the blood, but also in the lining of the respiratory tract and the gastrointestinal tract. Immunoglobulins are produced with small variations that allow them to bind the millions of different microbes. There are 5 types; igg, igm, iga, IgD and ige. ...Read more
15
Celiac disease? Biopsy needed?Endomysial AB IGA Negative,Gliadin AB IGA High=16, Anti-Gliadin IGG A B High=22, t-transglutanimaze IGG Normal 1.7, t-transglutanimaze igA Normal 3.1, IGA Normal 186

Depends on symptoms: If severe symptoms a biopsy is always the gold standard for diagnosis.if mild may just want to do the gluten free diet. ...Read more
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16
Is IgG subclass 3 deficiency a primary or secondary immunodeficiency?

Great question: You already know that most folks who are discovered to have real igg3 deficiency are troubled primarily by recurrent nasal sinus infections. Until we know whether there's one of more genes for this, or whether it's the result of some other change in the immune system (igg3 can drop after other illnesses), i think the mainstream medical community will remain undecided. Glad you're proactive. ...Read more
17
IMy HBV test results (red cross): Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Do I have HBV?

Cured, but...: If a person's Hep B surface antigen is nonreactive, that means the lab does not find pieces of the surface of the virus. If her Hep B virus PCR is negative, that means the lab does not find the virus's DNA (genes). If the core antibody is reactive that means her immune system REMEMBERS being infected with Hep B. She is cured, but some viral DNA might be attached to her own human DNA in her liver. ...Read more
18
Candida antibody IgM high 1.2. Candida antibody IgG high 1.9. Candida antibody IgA high 1.5. What does this mean? Yeast overgrowth?

Nothing: Every human gas been exposed to candida. Who is testing you when all tests will be positive? A physician? ...Read more
19
Does intravenous immunoglobulin (ivig) infusions benefit someone with IgG defiency?
Possibly: If you are deficient and symptomatic (recurrent infections), they can possibly help your body fight infections better. Just because you have an igg deficiency does not mean your are immune deficient, however. Many people with low numbers have normal function and really are asymptomatic. ...Read more
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20
Is immune globulin antibodies a medication?

IVIg, SCIg: Immunoglobulins are proteins that aour body produce with the major function of neutralizing microbes. They are also called antibodies. Some people are congenitally deficient and receive a concentrate of immunoglobulins prepared from blood donors. When given intravenously is called ivig, given subcutaneously is scig. Another function is anti-inflammation, and is used in autoimmune conditions. ...Read more
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