Doctor insights on:
Pleomorphic Sarcoma Prognosis
By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more
Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read moreSee 1 more doctor answer
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?
Pancoast tumor: Occurs at the top of the lung and invades out and up to involve muscles, nerves, and thereby causing pain and horner's syndrome. Metastasis usually means going to another organ. If confined to chest and outward extension (?Metastasis), outlook is more optimistic. If it metastasized to brain, lung, liver or distant bones, the outlook is bleak, seek symptom management, there is no cure. ...Read moreSee 1 more doctor answer
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
Yes: Neurofibromatosis type 1 and type 2 are both hereditary diseases. Malignant tumors like sarcomas are a rare complication of neurofibromatosis. The technical name given to these are "malignant peripheral nerve sheath tumors, " and these are a type of sarcoma. Here's a link to a free full text article on the subject: http://theoncologist.Alphamedpress.Org/content/5/6/477.Full. ...Read more
Nothing: Even in the lung, squamous cell carcinomas are usually silent until they have become large enough to cause coughing up of blood -- one of the common ways in which it announces itself. On the skin, of course, a growing mass with a rough surface is (depending on how it looks) likely to be a squamous skin cancer; these are usually easy to cure. Good luck. ...Read more
Many organs: The first likely tissue where metastases occurs in invasive ductal cancer is the lymph nodes on the armpit or behind the chest wall. Other organs may include the bones, lungs, liver, brain, adrenal glands, skin, bone marrow, the lining around the lungs or heart or the abdomen. Other parts of the body are less often sites of spread. ...Read more
Depends: Lymph nodes are one aspect of evaluation for stage and treatment of breast cancer. It depends on size of breast cancer itself, number of lymph nodes involved, hormone status of the tumor, and dna testing can also help identify breast cancer risks. If the lymph node involvement is small, then there is little additioanl risk to the patient. There are many factors involved in assessing breast cancer. ...Read more
Yes. It is a: Disease affecting young men, "always" under 30, teens most common, tending to arise in bones, and metastases to other bones and lung. When caught in the originating bone, usually with pain, or even fracture, before metastasis, it can be cured. Once metastatic, cure is not likely. Ergo, it can be fatal. ...Read moreSee 2 more doctor answers
MFH: Malignant fibrous histiocytoma is an umbrella term used to describe a range of more specific sarcomas. Although many of these tumors have unique cytogenetic profiles, they are largely not hereditary. ...Read more
Different lesions: A sarcoma is a malignant lesion arising from connective and not glandular tissue such as visceral leiomyosarcoma of uterus or stomach. metastatic disease represents spread of tumor that may arise from a sarcoma or carcinoma, lymphoma is a malignant form of blood cellular disease and paraganglioma is the benign form of the lesion arising from nerve tissue. All represent different forms of disease. ...Read more
We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. The ...Read more
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