Doctor insights on:
Pleomorphic Lobular Carcinoma Of The Breast
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
What are the causes of breast and arm pain after having biopsy with lobular carcinoma in situ diagnosis?
LCIS : Lobular-carcinoma-in-situ (lcis) is a microscopic finding on breast biopsy that is associated with an increased risk of breast cancer in either breast of those affected. It is silent in that it causes no symptoms. Therefore, your breast & arm pain is unrelated to the diagnosis. Perhaps the pain is related to the biopsy procedure itself. If so, it should resolve pretty quickly. ...Read more
Had mgram which showed pleomorphic calcs in r breast. Have biopsy in monday. What is rate of cancer assoc with this type? Can they be benign too?
Needs investigation: Although breast calcifications may not necessarily mean cancer, pleomorphic calcifications are suspicious. A biopsy should be done. Talk to your doctor. Pleomorphism means that something is of varying shape and characteristics. A non-cancerous or benign calcification will be read as "benign-appearing". Don't delay your biopsy. ...Read moreSee 2 more doctor answers
Biopsy: The only way to make a diagnosis of ilc is by biopsy (usually needle biopsy). The problem with ilc is that it often does not show up on a mammogram or sonogram until it is large or a lump can be felt. That is why the diagnosis of ilc is often made later than other types of breast cancer. ...Read moreSee 1 more doctor answer
Good: Lobular breast cancer is more frequently multifocal and bilateral than ductal carcinoma. However, with mastectomy (lumpectomy may not be sufficient) and sentinel lymph node biopsy, with follow-up hormone therapy and/or radiation should yield a good outcome, depending on the grade and stage of the cancer. Stage is most important, along with hormone receptor status. ...Read moreSee 1 more doctor answer
Also called lobular: Neoplasia...It forecasts that you will develop a breast cancer in either breast. Some used to do "mirror" biopsies. Others contemplate bilateral mastectomy. Lcis is a risk not a cancer, but the lobular invasive cancer can pose detection problems. Discuss this with a breast cancer team. I would watch very carefully. Lobular cancer makes up only 15% of invasive cancer. ...Read more
We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. The ...Read more
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