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Doctor insights on: Pleomorphic Calcifications Breast

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Dr. Ester Kwok Dr. Kwok
13 doctors agreed:
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Mammogram with punctate pleomorphic calcifications. Is that breast cancer?

Dr. Ester Kwok Dr. Kwok
13 doctors agreed:
Mammogram with punctate pleomorphic calcifications.  Is that breast cancer?

Needs investigation: Although breast calcifications may not necessarily mean cancer, pleomorphic calcifications are suspicious. A biopsy should be done. Talk to your doctor. Pleomorphism means that something is of varying shape and characteristics. A non-cancerous or benign calcification will be read as "benign-appearing". Don't delay your biopsy. ...Read more

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Pleomorphic (Definition)

We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. The ...Read more


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What is cystosarcoma phylloides breast lump, variant of fibroadenoma?

What is cystosarcoma phylloides breast lump, variant of fibroadenoma?

No; rare cancer: Cystosarcoma phyllodes is a cancerous variant of a tumor that is uncommon but usually benign (phyllodes tumors). They can be confused with fibroadenomas, BENIGN common tumors. Can grow to be quite large, usually painless; are best completely removed after diagnosis made. Unlike other breast cancer, don't spread to lymph nodes, but spread in blood. Chemo/radiation offered. They tend to recur. ...Read more

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39 yo extremely dense fibrocystic breasts w/well-circumscribed macrolobulated hypoechoic mass 11:00 left breast 3cm above nipple BIRAD 4? Cancer?

39 yo extremely dense fibrocystic breasts w/well-circumscribed macrolobulated hypoechoic mass 11:00 left breast 3cm above nipple BIRAD 4? Cancer?

No easy answer: It is imperative that you talk with the physician who took care of you. There are many possibilities and I would have to know more about these findings to give you my best opinion. ...Read more

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Breast tumor biopsy revealed 'canercous change'?

Breast tumor biopsy revealed 'canercous change'?

Need more info: "cancerous change" can mean many things. There are different pre-cancerous changes seen on breast biopsies, such as ADH (vasopressin) or alh (atypical ductal or atypical lobular hyperplasia). There are early cancers called dcis or lcis (ductal carcinoma in situ or lobular carcinoma in situ). Hopefully this is nothing, but we need more information. Make sure to follow-up with your doctor! ...Read more

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Mammogram results: 10mm lobulated nodule in left breast. Explain.

Mammogram results: 10mm lobulated nodule in left breast.  Explain.

That description: is not specific enough to venture a guess as to the level of suspicion. Other mammographic/sonographic features will determine how suspicious it is, and whether biopsy is indicated. Was this a screening mammo? Likely you will need additional mammo views and an ulltrasound for further evaluation. ...Read more

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Are fibrocystic breast lumps cancerous?

Are fibrocystic breast lumps cancerous?

Not usually: Fibrocystic breast disease is a disorder aggravated by coffee and smoking. However it is not a precursor to malignancy. Fibrocystic breast disease makes mammogram interpretation more problematic. ...Read more

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Mammo shows Heterogeneously dense breasts Birads 2 Benign finding what does then mean Heterogeneously dense breast ?

Mammo shows Heterogeneously dense breasts Birads 2 Benign finding what does then mean Heterogeneously dense breast ?

Breast tissue variab: The breast tissue density among women is quite variable and ranges from dense to lucent and any degree of mixed forms(that is what heterogeneous means as opposed to homogeneous). The breast that is very dense can sometimes hide a small breast Cancer . That is why such women are advised to have examination with an ultrasound in addition to mammography. You do not seem to have that problem. ...Read more

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Suspicious clusters of pleomorphic calcifications found on one breast only during mammogram?

Suspicious clusters of pleomorphic calcifications found on one breast only during mammogram?

Needs biopsy: Suspicious cluster opleomorphic microcalcifications on mgram may be due to breast cancer. Therefore you need to undergo a biopsy. Usually they sggest a stereotactic biopsy which is a type od percutaneous needle biopsy n a special x-ray table. Please follow with a breast carer specialist or a radiologist experien in this procedure. ...Read more

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Breastduct excision fibrocystic changes,ductal hyperplasia w/o atypical,apocrine metaplasia,dilated benign ducts with thermal artifact.this means what?

Breastduct excision fibrocystic changes,ductal hyperplasia w/o atypical,apocrine metaplasia,dilated benign ducts with thermal artifact.this means what?

No cancer: All of the changes in your breast are benign and there is no cancer. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Are breast lumps cancerous?

Are breast lumps cancerous?

Many Possibilities: The breast by its very nature is "lumpy-bumpy", often making it difficult to distinguish lumps that count from normal breat tissue. Lumps "that count" (dominant masses) tend to be distinct from normal breast tissue. They may be fluid-filled (cysts) or solid (tumors)--this can be differentiated by ultrasound. Tumors may be benign or malignant--this can be differentiated by biopsy. ...Read more

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History invasive breast cancer, US of thyroid show multiple solid nodule, largest 1.5 CM w/microcalcifications & hypervascularity. Odds of malignancy?

History invasive breast cancer, US of thyroid show multiple solid nodule, largest 1.5 CM w/microcalcifications & hypervascularity. Odds of malignancy?

Possible: most likely your doctor will do aspiration biopsy ( FNS ) in the office wait for the results , in general prognosis is excellent in most of the thyroid cancers . 44 yr old can expect cure , speak to your doctor ...Read more

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Are breast cancer lumps round?

Are breast cancer lumps round?

Yes possible: to be round usually irregular , if you find a lump must see your doctor ,if no recent mammography must have it ( in recent sensational study all woman who had lump had mammography ) if indicated biopsy is the option not delay for best out comes ...Read more

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What is breast cancer sentinel node micro metastases?

What is breast cancer sentinel node micro metastases?

Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read more

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3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. Cancer?

3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. Cancer?

Not necessarily...: The fact that FNA was reported as benign, the nodule is unlikely to be malignant. Small droplets of benign colloid often mimic "microcalcificatins" of papillary tumor, hence caution is advised. I would suggest repeating the FNA, and consider also collecting samples for gene profiling studies, such as, those manufactured by Veracyte and Asuragen (Note:I have no financial/other interest.) ...Read more

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What percentage of breast calcifications are benign?

What percentage of breast calcifications are benign?

Depends on age: 49 year old female asks, What percentage of breast calcifications are benign? Depends on shape and character. On Mammogram Bigger calcium deposits, Macrocalcifications, that tend to be rounded dots & scattered about tend to be benign and occurs in about 50% of women >50years & in about 10% of those ...Read more

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Mammo:ill marginated focal assymetry, sono:two lipomas or intramamary lymphs, mri:looks benign but birads 4, and recommends biopsy.Im confused/scared!

Mammo:ill marginated focal assymetry, sono:two lipomas or intramamary lymphs, mri:looks benign but birads 4, and recommends biopsy.Im confused/scared!

Seek expert opinion: I would advise that you consult a breast cancer surgeon or medical oncologist who has reputation of being a specialist in breast diseases/cancer. Based on your history, you may need to have a biopsy of the lumps/masses/ shadows that you have mentioned. That is the final solution to any palpable/visible lump in the breast. This will remove your anxiety which is due to the uncertainty you are facin. ...Read more

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Would a cancerous (lymphoma, breast cancer, etc.) axillary lymph node shrink?

Would a cancerous (lymphoma, breast cancer, etc.) axillary lymph node shrink?

No: A lymph node replaced with malignant cells growing as a primary lymphod tumor or metastatic from another site which has spread to axilla will not shrink without treatment, either chemo or RT. The node will enlarge further or if unchanged will spread to adjacent nodes. It does not have the potential to metastasize further to non lymphatic tissue such as liver or lung. ...Read more

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Complex cystic hypoechoic nodules right parotid gland with internal vascular septations &calcifications Echogenic foci Biopsy in future. Inconclusive?

Complex cystic hypoechoic nodules right parotid gland with internal vascular septations  &calcifications Echogenic foci Biopsy in future. Inconclusive?

Parotid mass: Your doctor will probably want an FNA, fine needle aspiration to obtain cells that can be examined by a pathologist. Probably will be benign but your ENT may suggest it be completely excised. ...Read more

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Palpable lumpin breast.Mammo-benign calcification biradsiii.Fnac-inflammatory lesion possibility of fat necrosis.Lump reduced.Taking antibiotics.Next?

Palpable lumpin breast.Mammo-benign calcification biradsiii.Fnac-inflammatory lesion possibility of fat necrosis.Lump reduced.Taking antibiotics.Next?

See your doctor: For follow up. Resolution of a benign inflammatory breast nodule is good news. May repeat breast ultrasound in a few months to confirm complete resolution, and mammogram in 6 months. ...Read more

Dr. Ester Kwok Dr. Kwok
13 doctors agreed:
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Mammogram with punctate pleomorphic calcifications. Is that breast cancer?

Dr. Ester Kwok Dr. Kwok
13 doctors agreed:

Needs investigation: Although breast calcifications may not necessarily mean cancer, pleomorphic calcifications are suspicious. A biopsy should be done. Talk to your doctor. Pleomorphism means that something is of varying shape and characteristics. A non-cancerous or benign calcification will be read as "benign-appearing". Don't delay your biopsy. ...Read more

See 4 more doctor answers
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Suspicious clusters of pleomorphic calcifications found on one breast only during mammogram?

Needs biopsy: Suspicious cluster opleomorphic microcalcifications on mgram may be due to breast cancer. Therefore you need to undergo a biopsy. Usually they sggest a stereotactic biopsy which is a type od percutaneous needle biopsy n a special x-ray table. Please follow with a breast carer specialist or a radiologist experien in this procedure. ...Read more

See 1 more doctor answer
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I have few scattered calcific foci in bilateral breast.No other focal lesion seen in mammogram of both breasts.Should i get worried?

I have few scattered calcific foci in bilateral breast.No other focal lesion seen in mammogram of both breasts.Should i get worried?

Concerned: And follow-up. To be calcified, these have existed for a while. Self and professional exams are important, along with excellent mammograms. Your gyn and / or breast specialist will follow with you. ...Read more

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Had mgram which showed pleomorphic calcs in r breast. Have biopsy in monday. What is rate of cancer assoc with this type? Can they be benign too?

Had mgram which showed pleomorphic calcs in r breast. Have biopsy in monday. What is rate of cancer assoc with this type? Can they be benign too?

Probably benign: There's about a 12% risk these will prove to be malignant. That leaves an 88% chance of benignancy. Good luck with the biopsy - i hope you get good results. ...Read more

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Internet info states that if breast calc are defined pleomorphic that risk of being malignant goes way up to 1 in 4. Is this true? Have biopsy mon

Internet info states that if breast calc are defined pleomorphic that risk of being malignant goes way up to 1 in 4. Is this true? Have biopsy mon

Relax: Relax until you get your results. Then, have the doctor explain until you understand - or have a close person along to also get the info. Before results there is nothing you can do - so try to stay calm. Afterwards ask for a referral to a supportive therapist to help you through the treatment choices. It can make a big difference in your outcome and adjustment. I hope it goes well for you. ...Read more

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Is there any connection between a swollen lymph node in the breast and clustered pleomorphic microcalcifications?

Is there any connection between a swollen lymph node in the breast and clustered pleomorphic microcalcifications?

Breast calcification: There may or may not be a connection. Microcalcifications can be present in both benign and malignant breast conditions. I'd consult with a breast surgeon to see if biopsies should be obtained now or would watchful waiting be reasonable. ...Read more

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Ct scan shows small calcific densities measuring 3.5mm in the right lobe of thyroid gland. Any suggestions on what this could be please? I had breast cancer in 08 but no mestateses and n full remission w br ca. Tysvm! I love you guys.

Ct scan shows small calcific densities measuring 3.5mm in the right lobe  of thyroid gland. Any suggestions on what this could be please? I had breast cancer in 08 but no mestateses and n full remission w br ca. Tysvm! I love you guys.

Many things: Thyroid calcifications are relatively common. Some of them are an indication of thyroid cancer. The first thing to do is to get a neck ultrasound, which is better than ct in visualizing the thyroid, and thyroid function tests. ...Read more

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Is it normal to have benign breast calcification surgically removed?

Is it normal to have benign breast calcification surgically removed?

Breast calcification: Benign breast calcifications do not have indication to be removed surgically. ...Read more

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My mammogram shows clustered pleomorphic calcification should I be worried ?

My mammogram shows clustered pleomorphic calcification should I be worried ?

Be concerned!: By your description a biopsy would be indicated. This can be performed with ultrasound guidance if there are findings by u/s in the region, or if not, with stereotactic guidance. These can easily be performed by a radiologist skilled in these procedures, or by a breast surgeon. This should be done as soon as possible. ...Read more

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What is calcification and non-invasive cancer of the breast like?

What is calcification and non-invasive cancer of the breast like?

If new merits eval: On mammogram calcifications can be seen frequently. Depending on their pattern and whether or not they are new, they can be characterized as either benign or suspicious appearing calcifications. This is a separate topic while related to noninvasive breast cancer which in most women is managed in a similar manner to invasive disease, other than no chemotherapy. This is a very large topic. Acs.Org. ...Read more

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If I was just diagnosed with a birad 4 micro calcification cluster in right breast, it looks linear and kinda branches out like a tree. CA likely?

Birad 4: is a "suspicious" calcification and needs BIOPSY! Hope this helps and remember EARLY detection is what it's all about!!! Good Luck and Hope this helps! Dr Z ...Read more

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I had cancerous calcification on my right breasts. I also had a lumpectomy and radiation, but why is the cancer coming back?

I had cancerous calcification on my right breasts. I also had a lumpectomy and radiation, but why is the cancer coming back?

We Wish We Knew: There is nothing more frustrating than cancer recurrence, especially when one is given a "clean bill of health" after treatment. Unfortunately, some breast cancers can recur--if its in the breast alone, a mastectomy may be necessary; if its elsewhere in the body, this requires chemotherapy. If you are unclear about this, please discuss at length with your cancer doctor. Good luck! ...Read more

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Ultrasound of breast didn't show lumps but instead calcification spots not in skin. Inconclusive, how worried should I be?

Ultrasound of breast didn't show lumps but instead calcification spots not in skin.  Inconclusive, how worried should I be?

Breast calcification: Calcifications in the breast tissue are seen frequently on mammography. The important distinction is whether they are clustered close together or spread out randomly in the breast tissue. Sometimes a better image is obtained by magnification views on mammogram, and if there is any suspicion of something serious then MRI would be good to do. A physical exam of the breasts is also important. ...Read more

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What is causing all my calcifications? In the breast, neck, fibroids (had hyst , )now need spleen removed because of calcification on it

What is causing all my calcifications? In the breast, neck, fibroids (had hyst , )now need spleen removed because of calcification on it

Calcifications: Have you been worked up by a physician for this issue? Calcification can be due to electrolyte abnormalities in the body as well as diet, genetics, alcohol intake, medications, etc... Consider seeing an endocrinologist for a thorough evaluation. ...Read more

Dr. John Kirk Dr. Kirk
2 doctors agreed:
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Both breasts show heterogeneous echopattern. No mass lesion or calcification seen.No evident ductal dilatation or skin thickening noted.Meaning?

Dr. John Kirk Dr. Kirk
2 doctors agreed:
Both breasts show heterogeneous echopattern. No mass lesion or calcification seen.No evident ductal dilatation or skin thickening noted.Meaning?

Likely benign: Imaging of the breast is imperfect at best. Heterogeneity in the breast is a common finding typically leading to class ii or birads 2 result on the mammogram. This is almost always a benign finding and is typical of a one-year follow-up repeat mammogram. The procedure is generally very low risk with very low levels of radiation. Get a clinical breast exam from your doctor and repeat mammo. ...Read more

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Calcification on left breast. Need a needle core biopsy. Feel swollen under left arm but don't feel a lump. Would my mammos detect underarm too?

Calcification on left breast.  Need a needle core biopsy.  Feel swollen under left arm but don't feel a lump.  Would my mammos detect underarm too?

Breast is priority: Your priority and that of the mammogram is to detect early breast lesions so that a needle biopsy dx can be rendered. The underarm swelling may be due to enlarged lymph nodes for which no x-ray is needed (you already know that they are enlarged). If the breast bx is malignant, the following step will be surgery that may include sampling of the lymph nodes (like sentinel node) . ...Read more

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Palpable lumpin breast.Mammo-benign calcification biradsiii.Fnac-inflammatory lesion possibility of fat necrosis.Lump reduced.Taking antibiotics.Next?

See your doctor: For follow up. Resolution of a benign inflammatory breast nodule is good news. May repeat breast ultrasound in a few months to confirm complete resolution, and mammogram in 6 months. ...Read more